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The map label for this gene is yrbE [H]

Identifier: 226225350

GI number: 226225350

Start: 2854109

End: 2855110

Strand: Reverse

Name: yrbE [H]

Synonym: Lm4b_02773

Alternate gene names: 226225350

Gene position: 2855110-2854109 (Counterclockwise)

Preceding gene: 226225351

Following gene: 226225349

Centisome position: 98.02

GC content: 39.72

Gene sequence:

>1002_bases
ATGACAAAGCAAATCAAAGTTGGCGTAATTGGCGTTGGACAAATGGGGCAGTATCATGCAGAAATTTACCAAAAGCTTCC
GCAAGTAGAGTTAGTAGCAATTTGTGAGTACAACGATGAAAGACGCGCCGAAATGGCAGAAAAATTTCAGTGTAAAGCAT
ACAAAGACTACCACGAACTTCTAGCAAATACGGAGATTGAAGCTGTGAGCATTGTTTTACCTGATAATATGCACCGTGAT
TGCGTGGAAGAAGCCGTAAAATACAAAAAACACATTTTACTCGAAAAACCACTTGCAAAAGAACTGGAAGACGGCAAAGC
AATGTATGAACTGACCAAAGACTACGACAAAGTGTTTACAGTTGGCTTTTTACTCAGATTTGATCCTCGTTTTAATATGA
TTAAACAGCGCCTCGATAACGGCGAATTGGGTGATATTATTCATCTTTATTGTCGTCGTAACAGCCCAATTACCGGGCCA
AAGCGTTACATAGGTGCTTCTGATTTAAGTATGCACGTAATGATTCACGATATTGATTATATTAACTGGTACATGGATAG
CGAGCCAGTCAAAGTTATTGCCAAAAGTCGCAGTGTTTTACTTAAAGAATACGGCATGAATGATGTGATTTATGCCATTG
TTACGTACGAAAATGGCGCAATTGCTTGCCTGGAAGCTTGCTGGGTCTTGCCAGAAAATTCACCAACCATCATTGACGAC
AAACTTGAATTAGTCGGAACAAAAGGCGTAGCATATGTAGACTCTTGCGACCACGGTGTTCGTTTTGTTAGTGAAAAAGG
GGTATCTTATCCGGATTCAAGACACTGGTATTACACAAATGGCGAAGTTTCCGGCGATTTAGCTGAGGAAGTAATGGCAT
TTATTAATAACGTGGCGAATAACACAAAATCAATTATTACACCAAAAGAAGCGTATGATTCCTTACGAGTAGTAGATGCG
ATTGAACGTTCGATTTCTGAGGGGAAAGAAGTATCACTATAA

Upstream 100 bases:

>100_bases
TATGCCGTTGTTGTTGGCGGCGCAGTAACTCGGCCACAGGAAATAACCACCCGCTTTACAAATGAAATTAAAAAAATCTA
AGAAGAAAGAGGTAAGTGAT

Downstream 100 bases:

>100_bases
AATAGCGCCACACATATGATTGGAGGGGGAAATATGTCTATTCGGGTACATGTACAAAAGTTTGGGAGTAAGCTAAGTGG
TATGGTCATTCCGAATTTGG

Product: dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTKQIKVGVIGVGQMGQYHAEIYQKLPQVELVAICEYNDERRAEMAEKFQCKAYKDYHELLANTEIEAVSIVLPDNMHRD
CVEEAVKYKKHILLEKPLAKELEDGKAMYELTKDYDKVFTVGFLLRFDPRFNMIKQRLDNGELGDIIHLYCRRNSPITGP
KRYIGASDLSMHVMIHDIDYINWYMDSEPVKVIAKSRSVLLKEYGMNDVIYAIVTYENGAIACLEACWVLPENSPTIIDD
KLELVGTKGVAYVDSCDHGVRFVSEKGVSYPDSRHWYYTNGEVSGDLAEEVMAFINNVANNTKSIITPKEAYDSLRVVDA
IERSISEGKEVSL

Sequences:

>Translated_333_residues
MTKQIKVGVIGVGQMGQYHAEIYQKLPQVELVAICEYNDERRAEMAEKFQCKAYKDYHELLANTEIEAVSIVLPDNMHRD
CVEEAVKYKKHILLEKPLAKELEDGKAMYELTKDYDKVFTVGFLLRFDPRFNMIKQRLDNGELGDIIHLYCRRNSPITGP
KRYIGASDLSMHVMIHDIDYINWYMDSEPVKVIAKSRSVLLKEYGMNDVIYAIVTYENGAIACLEACWVLPENSPTIIDD
KLELVGTKGVAYVDSCDHGVRFVSEKGVSYPDSRHWYYTNGEVSGDLAEEVMAFINNVANNTKSIITPKEAYDSLRVVDA
IERSISEGKEVSL
>Mature_332_residues
TKQIKVGVIGVGQMGQYHAEIYQKLPQVELVAICEYNDERRAEMAEKFQCKAYKDYHELLANTEIEAVSIVLPDNMHRDC
VEEAVKYKKHILLEKPLAKELEDGKAMYELTKDYDKVFTVGFLLRFDPRFNMIKQRLDNGELGDIIHLYCRRNSPITGPK
RYIGASDLSMHVMIHDIDYINWYMDSEPVKVIAKSRSVLLKEYGMNDVIYAIVTYENGAIACLEACWVLPENSPTIIDDK
LELVGTKGVAYVDSCDHGVRFVSEKGVSYPDSRHWYYTNGEVSGDLAEEVMAFINNVANNTKSIITPKEAYDSLRVVDAI
ERSISEGKEVSL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=366, Percent_Identity=22.9508196721311, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082405, Length=258, Percent_Identity=23.6434108527132, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323975, Length=345, Percent_Identity=22.3188405797101, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581117, Length=231, Percent_Identity=24.2424242424242, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37931; Mature: 37800

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQIKVGVIGVGQMGQYHAEIYQKLPQVELVAICEYNDERRAEMAEKFQCKAYKDYHEL
CCCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LANTEIEAVSIVLPDNMHRDCVEEAVKYKKHILLEKPLAKELEDGKAMYELTKDYDKVFT
HCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHH
VGFLLRFDPRFNMIKQRLDNGELGDIIHLYCRRNSPITGPKRYIGASDLSMHVMIHDIDY
HHHHEEECCCHHHHHHHCCCCCCCHHEEEEECCCCCCCCHHHHCCCCCCEEEEEEEEEEE
INWYMDSEPVKVIAKSRSVLLKEYGMNDVIYAIVTYENGAIACLEACWVLPENSPTIIDD
EEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEHHHEECCCCCCCEECC
KLELVGTKGVAYVDSCDHGVRFVSEKGVSYPDSRHWYYTNGEVSGDLAEEVMAFINNVAN
CEEEEECCCEEEECCCCCHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCC
NTKSIITPKEAYDSLRVVDAIERSISEGKEVSL
CCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKQIKVGVIGVGQMGQYHAEIYQKLPQVELVAICEYNDERRAEMAEKFQCKAYKDYHEL
CCEEEEEEEECCCCCHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
LANTEIEAVSIVLPDNMHRDCVEEAVKYKKHILLEKPLAKELEDGKAMYELTKDYDKVFT
HCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHH
VGFLLRFDPRFNMIKQRLDNGELGDIIHLYCRRNSPITGPKRYIGASDLSMHVMIHDIDY
HHHHEEECCCHHHHHHHCCCCCCCHHEEEEECCCCCCCCHHHHCCCCCCEEEEEEEEEEE
INWYMDSEPVKVIAKSRSVLLKEYGMNDVIYAIVTYENGAIACLEACWVLPENSPTIIDD
EEEEECCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCEEEEHHHEECCCCCCCEECC
KLELVGTKGVAYVDSCDHGVRFVSEKGVSYPDSRHWYYTNGEVSGDLAEEVMAFINNVAN
CEEEEECCCEEEECCCCCHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCC
NTKSIITPKEAYDSLRVVDAIERSISEGKEVSL
CCHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9025289 [H]