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The map label for this gene is kdpE [H]

Identifier: 226225229

GI number: 226225229

Start: 2720808

End: 2721503

Strand: Reverse

Name: kdpE [H]

Synonym: Lm4b_02651

Alternate gene names: 226225229

Gene position: 2721503-2720808 (Counterclockwise)

Preceding gene: 226225230

Following gene: 226225228

Centisome position: 93.44

GC content: 43.39

Gene sequence:

>696_bases
ATGAACAGCAAACGACTTGTGCTAATTGTGGAAGATGAAGAGGGTATCAGTAATTTTATTTCAGCTGTTTTGACTGCGAG
TGATTACTCGGTGATTAAAGCAGTGAATGGAAAAGAAGCGCTAGAGCAGACAGCAAGCCATTCGCCAGATGTTGTGCTAC
TCGACCTAGGTTTGCCCGATGTAGAAGGACTAGACGTGCTCCGTGATATTCGTGTTTGGTCAAAAGTGCCGATTATTGTT
GTATCCGCGCGCGATCACGAACGAGAGAAAGTGACGGCACTTGACCTTGGTGCAGATGATTATATTACGAAACCATTCGG
CACATCGGAACTACTGGCGCGGATTCGAACTGCCCTAAGACACATTCAACCAAGCAGCAAAGAAGCGCCAAATGATCATA
TTATTCGCATTCAAGACCTGTATATTGATGACGACCGCCGACTTGTCAAAATGGGAGATAAGGAAATTCATTTTACGCCA
ATTGAATATAAAATTTTGCTTCTATTAGCTCGCCACGCCGGAAAAGTCCTTACGCATGATTTTATTATTCGCGAAATTTG
GGGACCTTATCCAAGTGAAAACCAAGCACTTCGGGTCAATATGAGTAATATCCGACGTAAAATTGAACAAAATCCGGCAG
AACCTGCATACATTTTGACAGAAGTTGGGGTTGGATACCGGATGGCAGAAGAATAA

Upstream 100 bases:

>100_bases
CGATTATTCGAGCGCATGACGGGACTTTAGAAGCGAAAAATAACAAACATGGCGGGGCGACATTCTGGTTCACTTTGCCA
CTAGACGGAGGAGATGGAAA

Downstream 100 bases:

>100_bases
TAATATGTTATGATAAAAATAAACGCCAGGAGGAATTAATATGCATAAAACAATCCGTAGCGTAGACGTTTATTATGAAA
AATATGGTGAAGGAATACCG

Product: two components response regulator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNSKRLVLIVEDEEGISNFISAVLTASDYSVIKAVNGKEALEQTASHSPDVVLLDLGLPDVEGLDVLRDIRVWSKVPIIV
VSARDHEREKVTALDLGADDYITKPFGTSELLARIRTALRHIQPSSKEAPNDHIIRIQDLYIDDDRRLVKMGDKEIHFTP
IEYKILLLLARHAGKVLTHDFIIREIWGPYPSENQALRVNMSNIRRKIEQNPAEPAYILTEVGVGYRMAEE

Sequences:

>Translated_231_residues
MNSKRLVLIVEDEEGISNFISAVLTASDYSVIKAVNGKEALEQTASHSPDVVLLDLGLPDVEGLDVLRDIRVWSKVPIIV
VSARDHEREKVTALDLGADDYITKPFGTSELLARIRTALRHIQPSSKEAPNDHIIRIQDLYIDDDRRLVKMGDKEIHFTP
IEYKILLLLARHAGKVLTHDFIIREIWGPYPSENQALRVNMSNIRRKIEQNPAEPAYILTEVGVGYRMAEE
>Mature_231_residues
MNSKRLVLIVEDEEGISNFISAVLTASDYSVIKAVNGKEALEQTASHSPDVVLLDLGLPDVEGLDVLRDIRVWSKVPIIV
VSARDHEREKVTALDLGADDYITKPFGTSELLARIRTALRHIQPSSKEAPNDHIIRIQDLYIDDDRRLVKMGDKEIHFTP
IEYKILLLLARHAGKVLTHDFIIREIWGPYPSENQALRVNMSNIRRKIEQNPAEPAYILTEVGVGYRMAEE

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=44.8430493273543, Blast_Score=207, Evalue=6e-55,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=33.4801762114537, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.2678571428571, Blast_Score=122, Evalue=1e-29,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=30.1310043668122, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=228, Percent_Identity=31.5789473684211, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=31.304347826087, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=33.6283185840708, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI87082012, Length=221, Percent_Identity=30.7692307692308, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=29.6943231441048, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=27.6785714285714, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1790552, Length=226, Percent_Identity=33.6283185840708, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=28.9473684210526, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=28.3898305084746, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=29.7777777777778, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788550, Length=134, Percent_Identity=32.8358208955224, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=30.952380952381, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=30.4, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=100, Percent_Identity=31, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26113; Mature: 26113

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKRLVLIVEDEEGISNFISAVLTASDYSVIKAVNGKEALEQTASHSPDVVLLDLGLPD
CCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCCEEEEECCCCC
VEGLDVLRDIRVWSKVPIIVVSARDHEREKVTALDLGADDYITKPFGTSELLARIRTALR
CCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
HIQPSSKEAPNDHIIRIQDLYIDDDRRLVKMGDKEIHFTPIEYKILLLLARHAGKVLTHD
HCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHCCHHHHHH
FIIREIWGPYPSENQALRVNMSNIRRKIEQNPAEPAYILTEVGVGYRMAEE
HHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEEEEECCCCEEECCC
>Mature Secondary Structure
MNSKRLVLIVEDEEGISNFISAVLTASDYSVIKAVNGKEALEQTASHSPDVVLLDLGLPD
CCCCEEEEEEECCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHCCCCCEEEEECCCCC
VEGLDVLRDIRVWSKVPIIVVSARDHEREKVTALDLGADDYITKPFGTSELLARIRTALR
CCHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHH
HIQPSSKEAPNDHIIRIQDLYIDDDRRLVKMGDKEIHFTPIEYKILLLLARHAGKVLTHD
HCCCCCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEECCHHHHHHHHHHHHCCHHHHHH
FIIREIWGPYPSENQALRVNMSNIRRKIEQNPAEPAYILTEVGVGYRMAEE
HHHHHHCCCCCCCCCEEEEEHHHHHHHHHCCCCCCEEEEEECCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]