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The map label for this gene is uvrX [H]

Identifier: 226225227

GI number: 226225227

Start: 2718697

End: 2719953

Strand: Direct

Name: uvrX [H]

Synonym: Lm4b_02649

Alternate gene names: 226225227

Gene position: 2718697-2719953 (Clockwise)

Preceding gene: 226225226

Following gene: 226225234

Centisome position: 93.34

GC content: 41.29

Gene sequence:

>1257_bases
GTGCACCGCGCCGTGATATTTTGTGCATCGATATTAAATCGTTTTTTCGCCTCAGTTGAATGTGTCAAACGTCGGCTGAA
TCCACTTGAAGCATATTTAGTAGTAATGAGTAACGCCGACCGAGCTGGCGGGCTCGTTTTAGCTGCCACTCCAAAAATGA
AACAAGAACATCACATCAAAACCGGCTCAAGAATGTATGAACTGCCCACCTGGGATAAACGAATTATTATCGCACCCCCA
CGAATGAAACTTTATCTAAAAGTAAATGCGATGATTCAAGCCATTTTTAGACGTTATGTTCCCGCTGAGTTTATTCATGT
TTATAGTATTGATGAATGTTTTTTAGATATCACCGGATCGCATTTGTTATTCGGTAGCACGGAAGAAATTGTTCGCAAAA
TCCAGTGTGATATTTTAGAAGAATTGCGGCTATACGTTACAGTTGGAATCGGCGACAACCCTCTTCTTGCCAAACTCGCG
CTCGATAATGTGGCTAAAAACCGGGATGACGGCATTGCTGAATGGCGCTATGAAGACGTTCCCGAGACCATTTGGAAAAT
CAGACATTTGGATGATGTGTGCGGAATTGGGCGTCGGACTGCTGTTCGCCTGCAAAAAATGGGGATTTTCAATATGTATC
AACTAAGCCAAACGCCACCACAAGTGTTAAAAAACGCAATGGGTGTAGTCGGAGAGCAACTTTATTATCATGCTCACGGC
ATCGATTATAGTCTTTTAAATGAAAAATATGTTCCAGTTAGTAAAAGCTACGGAAAAAGCCAAATTCTTGAAAAAGACTA
TCATGTGCCGGCCGAAGTAGAGATTGTCATCCGCGAAATGGTTGAGGAAGTAGCAATGCGTTTACGCCAAAATCATGTGG
ATACTGCTGTTATTCATCTAAGTATCGGCTACAGTAAATACAGCATAAAAAAAGGATTCAGCCATCAAGCTAAAATCCCT
CCTACTAGTAGTAGTCATGCGCTTATTCCTTATTTCCTGCAACTATTTAGACGTTACGATGAACGCGAACCTGTGCGCTC
CATTGCTATTTCATGCGGTAAGATTACTTTGAAAACAGGGTTGCAGCTCAATTTATTTGAGGATGCTACTCGAACTTTAA
ATCATGAGCAGTTAGAAATAACTGTCGACAAAATCCGGTCGCGTTATGGTTTTAAATCACTTATGCATGCAAGCAGTTTA
TTAAATGGAGCGACTGGCTTAAAACGGTCTGAAATGGTTGGTGGTCACAAAGGTTAA

Upstream 100 bases:

>100_bases
CATTAAAAACTCTGAGGGGACTGTCCCGCTTTCCTTCTCTGCAATTCGCAATGTAGAAGAAAGGAGTGTCGAAAAATGGT
ACAAATAGAAGATTATAGCC

Downstream 100 bases:

>100_bases
CTTATTCTGGTTTCACGCGGAACAAGAAATCCTCTACCATTGTTGTAAATATTTTTGGTTGTTCAATTTGTAAATTATGT
CCTGCAAAATCAAGGATAGC

Product: UV-damage repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MHRAVIFCASILNRFFASVECVKRRLNPLEAYLVVMSNADRAGGLVLAATPKMKQEHHIKTGSRMYELPTWDKRIIIAPP
RMKLYLKVNAMIQAIFRRYVPAEFIHVYSIDECFLDITGSHLLFGSTEEIVRKIQCDILEELRLYVTVGIGDNPLLAKLA
LDNVAKNRDDGIAEWRYEDVPETIWKIRHLDDVCGIGRRTAVRLQKMGIFNMYQLSQTPPQVLKNAMGVVGEQLYYHAHG
IDYSLLNEKYVPVSKSYGKSQILEKDYHVPAEVEIVIREMVEEVAMRLRQNHVDTAVIHLSIGYSKYSIKKGFSHQAKIP
PTSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTGLQLNLFEDATRTLNHEQLEITVDKIRSRYGFKSLMHASSL
LNGATGLKRSEMVGGHKG

Sequences:

>Translated_418_residues
MHRAVIFCASILNRFFASVECVKRRLNPLEAYLVVMSNADRAGGLVLAATPKMKQEHHIKTGSRMYELPTWDKRIIIAPP
RMKLYLKVNAMIQAIFRRYVPAEFIHVYSIDECFLDITGSHLLFGSTEEIVRKIQCDILEELRLYVTVGIGDNPLLAKLA
LDNVAKNRDDGIAEWRYEDVPETIWKIRHLDDVCGIGRRTAVRLQKMGIFNMYQLSQTPPQVLKNAMGVVGEQLYYHAHG
IDYSLLNEKYVPVSKSYGKSQILEKDYHVPAEVEIVIREMVEEVAMRLRQNHVDTAVIHLSIGYSKYSIKKGFSHQAKIP
PTSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTGLQLNLFEDATRTLNHEQLEITVDKIRSRYGFKSLMHASSL
LNGATGLKRSEMVGGHKG
>Mature_418_residues
MHRAVIFCASILNRFFASVECVKRRLNPLEAYLVVMSNADRAGGLVLAATPKMKQEHHIKTGSRMYELPTWDKRIIIAPP
RMKLYLKVNAMIQAIFRRYVPAEFIHVYSIDECFLDITGSHLLFGSTEEIVRKIQCDILEELRLYVTVGIGDNPLLAKLA
LDNVAKNRDDGIAEWRYEDVPETIWKIRHLDDVCGIGRRTAVRLQKMGIFNMYQLSQTPPQVLKNAMGVVGEQLYYHAHG
IDYSLLNEKYVPVSKSYGKSQILEKDYHVPAEVEIVIREMVEEVAMRLRQNHVDTAVIHLSIGYSKYSIKKGFSHQAKIP
PTSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTGLQLNLFEDATRTLNHEQLEITVDKIRSRYGFKSLMHASSL
LNGATGLKRSEMVGGHKG

Specific function: Involved In Uv Protection And Mutation. Essential For Induced (Or Sos) Mutagenesis. May Modify The DNA Replication Machinery To Allow Bypass Synthesis Across A Damaged Template. [C]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=427, Percent_Identity=25.5269320843091, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI1786425, Length=287, Percent_Identity=26.8292682926829, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 47675; Mature: 47675

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRAVIFCASILNRFFASVECVKRRLNPLEAYLVVMSNADRAGGLVLAATPKMKQEHHIK
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCCCEEEEECCCCCHHHCCC
TGSRMYELPTWDKRIIIAPPRMKLYLKVNAMIQAIFRRYVPAEFIHVYSIDECFLDITGS
CCCEEEECCCCCCEEEEECCCEEEEEEHHHHHHHHHHHCCCHHHEEEEEHHHHHHCCCCC
HLLFGSTEEIVRKIQCDILEELRLYVTVGIGDNPLLAKLALDNVAKNRDDGIAEWRYEDV
EEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHCCCCCH
PETIWKIRHLDDVCGIGRRTAVRLQKMGIFNMYQLSQTPPQVLKNAMGVVGEQLYYHAHG
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHEECC
IDYSLLNEKYVPVSKSYGKSQILEKDYHVPAEVEIVIREMVEEVAMRLRQNHVDTAVIHL
CCHHHHCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SIGYSKYSIKKGFSHQAKIPPTSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTG
EECCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECC
LQLNLFEDATRTLNHEQLEITVDKIRSRYGFKSLMHASSLLNGATGLKRSEMVGGHKG
CEEEEHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC
>Mature Secondary Structure
MHRAVIFCASILNRFFASVECVKRRLNPLEAYLVVMSNADRAGGLVLAATPKMKQEHHIK
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCCCCCCEEEEECCCCCHHHCCC
TGSRMYELPTWDKRIIIAPPRMKLYLKVNAMIQAIFRRYVPAEFIHVYSIDECFLDITGS
CCCEEEECCCCCCEEEEECCCEEEEEEHHHHHHHHHHHCCCHHHEEEEEHHHHHHCCCCC
HLLFGSTEEIVRKIQCDILEELRLYVTVGIGDNPLLAKLALDNVAKNRDDGIAEWRYEDV
EEEECCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCHHCCCCCH
PETIWKIRHLDDVCGIGRRTAVRLQKMGIFNMYQLSQTPPQVLKNAMGVVGEQLYYHAHG
HHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHEECC
IDYSLLNEKYVPVSKSYGKSQILEKDYHVPAEVEIVIREMVEEVAMRLRQNHVDTAVIHL
CCHHHHCCCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
SIGYSKYSIKKGFSHQAKIPPTSSSHALIPYFLQLFRRYDEREPVRSIAISCGKITLKTG
EECCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHCCEEEEECC
LQLNLFEDATRTLNHEQLEITVDKIRSRYGFKSLMHASSLLNGATGLKRSEMVGGHKG
CEEEEHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9722542; 9384377 [H]