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The map label for this gene is gatC [H]

Identifier: 226225216

GI number: 226225216

Start: 2709984

End: 2711255

Strand: Reverse

Name: gatC [H]

Synonym: Lm4b_02638

Alternate gene names: 226225216

Gene position: 2711255-2709984 (Counterclockwise)

Preceding gene: 226225217

Following gene: 226225215

Centisome position: 93.08

GC content: 40.17

Gene sequence:

>1272_bases
ATGGATACACTTCTGTCAGGAGTACAGTATGTTTTAAACTTGGGGCCTACAGTTATTTTGCCTATTATGATTTTCTTTAT
TGCATTAATTTTCCGAGTACCAGCAAAGAAAGCGCTTCGTTCAGCGATTACGATTGGTATCGGGTTTGTAGGTATTAACC
TTGTTATTAGTTTACTATCTAGTAACTTAGGTCCGGCAGCGCAACAAATGGTTGAGCGTTTTGGACTGAATTTAACAATT
ATTGATGCAGGTTGGCCAGCAGCAGCCGCGGCTTCATGGGCTTCTCCAGTTGCAGCAATTTTAATTCCAATCTGTTTGGT
AGTTAACTTAGCACTTATTTTCTTCAAAGTTACGAAAACACTTGATATTGATATTTGGAACTACTGGCATTTCATCGCAG
CAGGTGCAACTGGTTATATCGTAACTGGTGGTAACTGGTGGTTCGCGATTCTTTGTGCGATCATCTATGAAGTTGCTGTT
CTTTGGATGGCAGACAGAACACAACCTATGGTAGAAGAATTTTACGGCTTAAAAGGGATCTCCTTACCAACAGGTTCTAC
AGCAGCATTCGGTTTCATCGGTATTCCGGTTGGTTGGCTAATCGCTAAAATCCCTGGTATTAAAAACATCCATGTTGACC
CAGAAACTATTCAAAAACGTTTTGGTATTTTCGGGGAACCAATGATGATGGGTCTTATTCTAGGTATTGCAATCGGTATT
CTTGCAGGCTATGACGTTGGCGCAGTTGCACAACTTGGTATGTCCATGGGTGCGGTAATGTTCTTAATGCCTCGTATGGT
TAAAATTTTAATGGAAGGTTTAATTCCAATTTCAGAATCCGCTCGTGAATTCATGAAATCTCGTTTCAAAGGCCGCGAAC
TTTATATCGGGCTTGATGCAGCACTTTCAATCGGTCACCCAGCGAATATTTCTACTGGTTTAATCCTTGTTCCAATCACT
CTTTTCTTAGCTGTTATCATTCCTGGTAACAAAGTACTTCCTTTTGGTGACTTGGCAACTATTCCATTCTACGTATCATT
CGTAGTAGCATCTCGTAAAGGTAACATTCTTCACTCTGTTTTAGCTGGAACTGTAGTTATTGCACTAGCGCTTCTTATGG
CAACTGACTTCGGTCTTGTTCATACAGAAATGATGAAAGGTGTTTACGAATTCCCTAAAGGAGCAACACAAGTTAGTACA
CTTGATATGGGTGGTAACTTCTTTAACTGGGTTATTCTTAAATTCTCTCAAGCTTGGGCAGCTATTTTCTAA

Upstream 100 bases:

>100_bases
GGAAGAATTAGACGAAGAAATACTTGCGCACCTTAAATAAAGGCTGCGCAAGGGAGTTTAGAAATCATCATTAAACAGAG
AAAAAAGGAGGAAATATTAA

Downstream 100 bases:

>100_bases
GTTTTGTCTTAATGATATAGAAGAGGTGATAGTAACATGAGAGCAGCTGTGTTATACGAGAATAATGTAATAAAAGCAGA
ACAAATTGATGAAGCGACTT

Product: PTS system galactitol-specific enzyme IIC component

Products: galactitol-1-phosphate [Cytoplasm]; pyruvate [C]

Alternate protein names: EIIC-Gat; PTS system galactitol-specific EIIC component [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MDTLLSGVQYVLNLGPTVILPIMIFFIALIFRVPAKKALRSAITIGIGFVGINLVISLLSSNLGPAAQQMVERFGLNLTI
IDAGWPAAAAASWASPVAAILIPICLVVNLALIFFKVTKTLDIDIWNYWHFIAAGATGYIVTGGNWWFAILCAIIYEVAV
LWMADRTQPMVEEFYGLKGISLPTGSTAAFGFIGIPVGWLIAKIPGIKNIHVDPETIQKRFGIFGEPMMMGLILGIAIGI
LAGYDVGAVAQLGMSMGAVMFLMPRMVKILMEGLIPISESAREFMKSRFKGRELYIGLDAALSIGHPANISTGLILVPIT
LFLAVIIPGNKVLPFGDLATIPFYVSFVVASRKGNILHSVLAGTVVIALALLMATDFGLVHTEMMKGVYEFPKGATQVST
LDMGGNFFNWVILKFSQAWAAIF

Sequences:

>Translated_423_residues
MDTLLSGVQYVLNLGPTVILPIMIFFIALIFRVPAKKALRSAITIGIGFVGINLVISLLSSNLGPAAQQMVERFGLNLTI
IDAGWPAAAAASWASPVAAILIPICLVVNLALIFFKVTKTLDIDIWNYWHFIAAGATGYIVTGGNWWFAILCAIIYEVAV
LWMADRTQPMVEEFYGLKGISLPTGSTAAFGFIGIPVGWLIAKIPGIKNIHVDPETIQKRFGIFGEPMMMGLILGIAIGI
LAGYDVGAVAQLGMSMGAVMFLMPRMVKILMEGLIPISESAREFMKSRFKGRELYIGLDAALSIGHPANISTGLILVPIT
LFLAVIIPGNKVLPFGDLATIPFYVSFVVASRKGNILHSVLAGTVVIALALLMATDFGLVHTEMMKGVYEFPKGATQVST
LDMGGNFFNWVILKFSQAWAAIF
>Mature_423_residues
MDTLLSGVQYVLNLGPTVILPIMIFFIALIFRVPAKKALRSAITIGIGFVGINLVISLLSSNLGPAAQQMVERFGLNLTI
IDAGWPAAAAASWASPVAAILIPICLVVNLALIFFKVTKTLDIDIWNYWHFIAAGATGYIVTGGNWWFAILCAIIYEVAV
LWMADRTQPMVEEFYGLKGISLPTGSTAAFGFIGIPVGWLIAKIPGIKNIHVDPETIQKRFGIFGEPMMMGLILGIAIGI
LAGYDVGAVAQLGMSMGAVMFLMPRMVKILMEGLIPISESAREFMKSRFKGRELYIGLDAALSIGHPANISTGLILVPIT
LFLAVIIPGNKVLPFGDLATIPFYVSFVVASRKGNILHSVLAGTVVIALALLMATDFGLVHTEMMKGVYEFPKGATQVST
LDMGGNFFNWVILKFSQAWAAIF

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3775

COG function: function code G; Phosphotransferase system, galactitol-specific IIC component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788408, Length=407, Percent_Identity=41.031941031941, Blast_Score=339, Evalue=2e-94,
Organism=Escherichia coli, GI1790758, Length=409, Percent_Identity=40.5867970660147, Blast_Score=310, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013853
- InterPro:   IPR013014
- InterPro:   IPR004703 [H]

Pfam domain/function: PF03611 EIIC-GAT [H]

EC number: NA

Molecular weight: Translated: 45573; Mature: 45573

Theoretical pI: Translated: 8.96; Mature: 8.96

Prosite motif: PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTLLSGVQYVLNLGPTVILPIMIFFIALIFRVPAKKALRSAITIGIGFVGINLVISLLS
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SNLGPAAQQMVERFGLNLTIIDAGWPAAAAASWASPVAAILIPICLVVNLALIFFKVTKT
CCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDIDIWNYWHFIAAGATGYIVTGGNWWFAILCAIIYEVAVLWMADRTQPMVEEFYGLKGI
EEEEHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
SLPTGSTAAFGFIGIPVGWLIAKIPGIKNIHVDPETIQKRFGIFGEPMMMGLILGIAIGI
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHH
LAGYDVGAVAQLGMSMGAVMFLMPRMVKILMEGLIPISESAREFMKSRFKGRELYIGLDA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEHH
ALSIGHPANISTGLILVPITLFLAVIIPGNKVLPFGDLATIPFYVSFVVASRKGNILHSV
HEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
LAGTVVIALALLMATDFGLVHTEMMKGVYEFPKGATQVSTLDMGGNFFNWVILKFSQAWA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
AIF
HCC
>Mature Secondary Structure
MDTLLSGVQYVLNLGPTVILPIMIFFIALIFRVPAKKALRSAITIGIGFVGINLVISLLS
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SNLGPAAQQMVERFGLNLTIIDAGWPAAAAASWASPVAAILIPICLVVNLALIFFKVTKT
CCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDIDIWNYWHFIAAGATGYIVTGGNWWFAILCAIIYEVAVLWMADRTQPMVEEFYGLKGI
EEEEHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCC
SLPTGSTAAFGFIGIPVGWLIAKIPGIKNIHVDPETIQKRFGIFGEPMMMGLILGIAIGI
CCCCCCCHHHHHHHHHHHHHHHHCCCCCEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHH
LAGYDVGAVAQLGMSMGAVMFLMPRMVKILMEGLIPISESAREFMKSRFKGRELYIGLDA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEEHH
ALSIGHPANISTGLILVPITLFLAVIIPGNKVLPFGDLATIPFYVSFVVASRKGNILHSV
HEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
LAGTVVIALALLMATDFGLVHTEMMKGVYEFPKGATQVSTLDMGGNFFNWVILKFSQAWA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHH
AIF
HCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phosphoenolpyruvate; galactitol [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + galactitol [Periplasm] = galactitol-1-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]