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The map label for this gene is oppC [H]

Identifier: 226224802

GI number: 226224802

Start: 2288243

End: 2289277

Strand: Reverse

Name: oppC [H]

Synonym: Lm4b_02221

Alternate gene names: 226224802

Gene position: 2289277-2288243 (Counterclockwise)

Preceding gene: 226224803

Following gene: 226224801

Centisome position: 78.6

GC content: 36.14

Gene sequence:

>1035_bases
ATGGCAGAACATAAAATTGCAAAAGAAAGATTTCAGCCAGCACACATTCTGGATGCAGAAGCAGAGAAAATTAATCGTCC
AAGTTTAACTTTCTTGCAAGATTCTTGGCTTCGTATTCGTAAAAATAAAGCGGCTTTAGTTTCTCTAATTGTATTAGCAC
TTGTTATTATCATGGCAATTGTTGGGCCTTATTTATCACAAAATCTAGGACCAAAACATGATATTAACCGACAAATCACT
GAAAATGCGAGTCTTCCTCCAAAAGTTCAAGGCTTTGAAAATATGCCTTTCTGGAATGGTCATCAATCTATTGGTGGAGA
AGATGTTGATATTTATAAACAAAATAATATTAAAGAGGGTACTTACTACTGGTTAGGTAGTGATACGCTTGGACGTGACC
AATTTGCTCGTATTTGGGCTGGTACACGTGTATCTCTTATTATTGCTGTTGTAGCAGCGCTTTGTGACCTTATAATTGGG
GTTGCTTACGGTTTGATTTCTGGTTATGTTGGAGGCCGTGTAGATAATTTCATGCAACGTGTTTTAGAAGTTATTGGTGC
AATTCCAAACTTAGTTGTGGTTATTTTAATGATGTTAATACTCGAACCAGGTATTGTATCTATTATCATAGCAATCGCAA
TGACGAGTTGGATAACGATGGCCCGGGTAGTCAGGGGACAAGTTTTAAAACTTAAAAACCAAGAATTTGTTATGGCTTCC
ATGACTTTAGGGGAATCTACTCCTAAAATTCTTATAAAACATTTAATACCAAATATTTCTGGGATTATTATCATTAACAT
CATGTTTAGTATTCCTAGTGCGATTTTCTTTGAAGCCTTCTTAAGCTTTATTGGGCTTGGTCTTCCAGCGCCAGCAGCGT
CTCTTGGTGTCTTGGTAAATGATGGATATAAAACATTACAAGTATTACCGTATATGATTCTGTATCCATGTATTGTACTT
TGTATCATTATGATTGCATTTAACTTAATTGCAGATGGCTTGCGTGATGCCTTCGATCCTAAAATGCGCGATTAA

Upstream 100 bases:

>100_bases
CAATTTTATTTGCTGTCATGTTGGTATTTGTTATCTTGGTAGTGGATATTCTTTACGGATTGATTGATCCTCGAATCCGT
GTGTCTGGAGGTAGAAAATA

Downstream 100 bases:

>100_bases
AAGAGAGGTGAGGAAAAATGGAAAAGCTATTAGAAGTTAAAGATTTAAATATTTCATTCCACACATATGCCGGTGAAGTA
AAGGCGATTCGTGGAGTTAA

Product: oligopeptide ABC transporter (permease)

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: Stage 0 sporulation protein KC [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MAEHKIAKERFQPAHILDAEAEKINRPSLTFLQDSWLRIRKNKAALVSLIVLALVIIMAIVGPYLSQNLGPKHDINRQIT
ENASLPPKVQGFENMPFWNGHQSIGGEDVDIYKQNNIKEGTYYWLGSDTLGRDQFARIWAGTRVSLIIAVVAALCDLIIG
VAYGLISGYVGGRVDNFMQRVLEVIGAIPNLVVVILMMLILEPGIVSIIIAIAMTSWITMARVVRGQVLKLKNQEFVMAS
MTLGESTPKILIKHLIPNISGIIIINIMFSIPSAIFFEAFLSFIGLGLPAPAASLGVLVNDGYKTLQVLPYMILYPCIVL
CIIMIAFNLIADGLRDAFDPKMRD

Sequences:

>Translated_344_residues
MAEHKIAKERFQPAHILDAEAEKINRPSLTFLQDSWLRIRKNKAALVSLIVLALVIIMAIVGPYLSQNLGPKHDINRQIT
ENASLPPKVQGFENMPFWNGHQSIGGEDVDIYKQNNIKEGTYYWLGSDTLGRDQFARIWAGTRVSLIIAVVAALCDLIIG
VAYGLISGYVGGRVDNFMQRVLEVIGAIPNLVVVILMMLILEPGIVSIIIAIAMTSWITMARVVRGQVLKLKNQEFVMAS
MTLGESTPKILIKHLIPNISGIIIINIMFSIPSAIFFEAFLSFIGLGLPAPAASLGVLVNDGYKTLQVLPYMILYPCIVL
CIIMIAFNLIADGLRDAFDPKMRD
>Mature_343_residues
AEHKIAKERFQPAHILDAEAEKINRPSLTFLQDSWLRIRKNKAALVSLIVLALVIIMAIVGPYLSQNLGPKHDINRQITE
NASLPPKVQGFENMPFWNGHQSIGGEDVDIYKQNNIKEGTYYWLGSDTLGRDQFARIWAGTRVSLIIAVVAALCDLIIGV
AYGLISGYVGGRVDNFMQRVLEVIGAIPNLVVVILMMLILEPGIVSIIIAIAMTSWITMARVVRGQVLKLKNQEFVMASM
TLGESTPKILIKHLIPNISGIIIINIMFSIPSAIFFEAFLSFIGLGLPAPAASLGVLVNDGYKTLQVLPYMILYPCIVLC
IIMIAFNLIADGLRDAFDPKMRD

Specific function: Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence [H]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787498, Length=332, Percent_Identity=36.4457831325301, Blast_Score=197, Evalue=8e-52,
Organism=Escherichia coli, GI1787054, Length=315, Percent_Identity=29.2063492063492, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789889, Length=220, Percent_Identity=36.3636363636364, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788505, Length=218, Percent_Identity=33.0275229357798, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1787760, Length=219, Percent_Identity=31.9634703196347, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789964, Length=325, Percent_Identity=28, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787549, Length=313, Percent_Identity=24.6006389776358, Blast_Score=98, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 37986; Mature: 37855

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEHKIAKERFQPAHILDAEAEKINRPSLTFLQDSWLRIRKNKAALVSLIVLALVIIMAI
CCCCHHHHHHCCCCHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGPYLSQNLGPKHDINRQITENASLPPKVQGFENMPFWNGHQSIGGEDVDIYKQNNIKEG
HHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
TYYWLGSDTLGRDQFARIWAGTRVSLIIAVVAALCDLIIGVAYGLISGYVGGRVDNFMQR
CEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VLEVIGAIPNLVVVILMMLILEPGIVSIIIAIAMTSWITMARVVRGQVLKLKNQEFVMAS
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
MTLGESTPKILIKHLIPNISGIIIINIMFSIPSAIFFEAFLSFIGLGLPAPAASLGVLVN
HHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEC
DGYKTLQVLPYMILYPCIVLCIIMIAFNLIADGLRDAFDPKMRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AEHKIAKERFQPAHILDAEAEKINRPSLTFLQDSWLRIRKNKAALVSLIVLALVIIMAI
CCCHHHHHHCCCCHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGPYLSQNLGPKHDINRQITENASLPPKVQGFENMPFWNGHQSIGGEDVDIYKQNNIKEG
HHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCC
TYYWLGSDTLGRDQFARIWAGTRVSLIIAVVAALCDLIIGVAYGLISGYVGGRVDNFMQR
CEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VLEVIGAIPNLVVVILMMLILEPGIVSIIIAIAMTSWITMARVVRGQVLKLKNQEFVMAS
HHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
MTLGESTPKILIKHLIPNISGIIIINIMFSIPSAIFFEAFLSFIGLGLPAPAASLGVLVN
HHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEC
DGYKTLQVLPYMILYPCIVLCIIMIAFNLIADGLRDAFDPKMRD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1901616; 1899858; 9384377 [H]