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The map label for this gene is xerD [H]

Identifier: 226224560

GI number: 226224560

Start: 2023861

End: 2024754

Strand: Reverse

Name: xerD [H]

Synonym: Lm4b_01974

Alternate gene names: 226224560

Gene position: 2024754-2023861 (Counterclockwise)

Preceding gene: 226224561

Following gene: 226224559

Centisome position: 69.51

GC content: 39.04

Gene sequence:

>894_bases
ATGAATGATTTAATAGAAGATTTTTTACATTTTTTAATTGTAGAGAGAGGTTTATCCGCGAATACAATCAAAGCTTATGA
ACGAGATTTACGCTATTTTGTTTCTTATATGGATGTAGCGAAGGGATTAACAGATCCGAATACACTTGAACGAAGCGATA
TAGTTGGTTTTATGGCATTTGCAAGACAAGAAGGGAAATCAGCAAGAAGTGTGGCGCGCTATATTGCTTCACTGCGATCT
TTCTTTCATTATTTAATGCACGATGGGAAAATGTCACATGACCCAATGATTCAAATTGAAACGCCGAAGCAAGCTCAGGG
ATTACCAAAAGTTTTGAACCTTGATGATGTCGAGAAGTTACTTAGTTCCTCTGATACGAGTACACCACTTGGATTAAGGG
ACCAAGCAATGATGGAAATTTTATATGCGACAGGGCTTCGTGTAACGGAACTTGTCAGCCTGAAAATGGACGATTTACAT
CTTCATATGGGTTTTATTCAAACGATTGGTAAAGGAGATAAAGAAAGAATTATCCCGCTTGGAAAAACGGCAACAACTGT
GTTAGAGAAGTATTTAGAGGAAGCGAGACCAAAACTTCGTAGACCGAAATACCGAAATGATTTTGTGTTTTTAAATCATC
ACGGCCAAGGACTCACAAGACAAGGTTTCTGGAAAATTTTAAAAGGTATTGCGAAAGAATCAGGCATTGAAAAGCCGATT
ACACCGCACACCTTGCGTCATTCATTTGCCACTCATTTACTTGAAAATGGGGCTGATTTAAGGTCGGTTCAAGAACTCCT
TGGTCACGCCGATATCTCCACTACACAAATTTATACACACGTAACAAAGCTGCGGTTGAAAGATGTCTACAAACAATTCC
ACCCGCGCGCTTAA

Upstream 100 bases:

>100_bases
GACTGAATTGCGCGAAAAGTATTATAAGTCTTTTTCTATTAATTAAACGTTTTCAGTGGGAGTGTAACATGGTAGAATAG
GATTTGTGGAGGAAACGCTT

Downstream 100 bases:

>100_bases
AAAATATAGTTGAAAAGGATGAGTAAATATGCCAGATAAATTTAAACGAGTACATGTAGTTGTAATGGATTCAGTTGGTA
TTGGAGAAGCGCCAGATGCT

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNDLIEDFLHFLIVERGLSANTIKAYERDLRYFVSYMDVAKGLTDPNTLERSDIVGFMAFARQEGKSARSVARYIASLRS
FFHYLMHDGKMSHDPMIQIETPKQAQGLPKVLNLDDVEKLLSSSDTSTPLGLRDQAMMEILYATGLRVTELVSLKMDDLH
LHMGFIQTIGKGDKERIIPLGKTATTVLEKYLEEARPKLRRPKYRNDFVFLNHHGQGLTRQGFWKILKGIAKESGIEKPI
TPHTLRHSFATHLLENGADLRSVQELLGHADISTTQIYTHVTKLRLKDVYKQFHPRA

Sequences:

>Translated_297_residues
MNDLIEDFLHFLIVERGLSANTIKAYERDLRYFVSYMDVAKGLTDPNTLERSDIVGFMAFARQEGKSARSVARYIASLRS
FFHYLMHDGKMSHDPMIQIETPKQAQGLPKVLNLDDVEKLLSSSDTSTPLGLRDQAMMEILYATGLRVTELVSLKMDDLH
LHMGFIQTIGKGDKERIIPLGKTATTVLEKYLEEARPKLRRPKYRNDFVFLNHHGQGLTRQGFWKILKGIAKESGIEKPI
TPHTLRHSFATHLLENGADLRSVQELLGHADISTTQIYTHVTKLRLKDVYKQFHPRA
>Mature_297_residues
MNDLIEDFLHFLIVERGLSANTIKAYERDLRYFVSYMDVAKGLTDPNTLERSDIVGFMAFARQEGKSARSVARYIASLRS
FFHYLMHDGKMSHDPMIQIETPKQAQGLPKVLNLDDVEKLLSSSDTSTPLGLRDQAMMEILYATGLRVTELVSLKMDDLH
LHMGFIQTIGKGDKERIIPLGKTATTVLEKYLEEARPKLRRPKYRNDFVFLNHHGQGLTRQGFWKILKGIAKESGIEKPI
TPHTLRHSFATHLLENGADLRSVQELLGHADISTTQIYTHVTKLRLKDVYKQFHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=46.5986394557823, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1790244, Length=301, Percent_Identity=38.2059800664452, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1790768, Length=163, Percent_Identity=30.6748466257669, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790767, Length=181, Percent_Identity=28.1767955801105, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33933; Mature: 33933

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDLIEDFLHFLIVERGLSANTIKAYERDLRYFVSYMDVAKGLTDPNTLERSDIVGFMAF
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ARQEGKSARSVARYIASLRSFFHYLMHDGKMSHDPMIQIETPKQAQGLPKVLNLDDVEKL
HHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCCCCCHHHHHHH
LSSSDTSTPLGLRDQAMMEILYATGLRVTELVSLKMDDLHLHMGFIQTIGKGDKERIIPL
HCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
GKTATTVLEKYLEEARPKLRRPKYRNDFVFLNHHGQGLTRQGFWKILKGIAKESGIEKPI
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
TPHTLRHSFATHLLENGADLRSVQELLGHADISTTQIYTHVTKLRLKDVYKQFHPRA
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDLIEDFLHFLIVERGLSANTIKAYERDLRYFVSYMDVAKGLTDPNTLERSDIVGFMAF
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
ARQEGKSARSVARYIASLRSFFHYLMHDGKMSHDPMIQIETPKQAQGLPKVLNLDDVEKL
HHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHCCCCCCCCHHHHHHH
LSSSDTSTPLGLRDQAMMEILYATGLRVTELVSLKMDDLHLHMGFIQTIGKGDKERIIPL
HCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
GKTATTVLEKYLEEARPKLRRPKYRNDFVFLNHHGQGLTRQGFWKILKGIAKESGIEKPI
CHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCC
TPHTLRHSFATHLLENGADLRSVQELLGHADISTTQIYTHVTKLRLKDVYKQFHPRA
CHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]