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The map label for this gene is dapB

Identifier: 226224511

GI number: 226224511

Start: 1968376

End: 1969167

Strand: Reverse

Name: dapB

Synonym: Lm4b_01924

Alternate gene names: 226224511

Gene position: 1969167-1968376 (Counterclockwise)

Preceding gene: 226224512

Following gene: 226224510

Centisome position: 67.61

GC content: 38.64

Gene sequence:

>792_bases
ATGAGAGTAGCAGTATCTGGATTTAAAGGAAGAATGGGACACGAGGTTGTCAAAACTGTTTTAAGAGAAGCAGATTTAGA
GTTAGTAGCCGTACTTGACCATGAACCAAAAGAAAAAAATATAAATGAAATAGTGGAATTTAGCTCGTTAGATGTACCTG
TTTTTGGTAATTTAAGCGAGATGTTAGAAGAAATAAAACCGGATTGTGTCGTTGATTTTACGACCCCTAAAGTAGGGTAT
AGTAACACGAAAACGATTTTAGAACACGGCGTACGTGCGGTCGTTGGTACAACAGGTTTTACACCAGAACAAATTAGTGA
ACTAAGATCAATTGCAGAATCGAAAAAAATCGGTGCGTTAATTGCGCCAAACTTTGCTGTAGGCGCTGTTTTAATGATGC
AATTTGCACAAAAAGCAGCTAAGTATTTCCCGAACGTCGAAATTATTGAGTTGCACCATGACAATAAATTAGACGCGCCA
AGTGGTACGGCTGTTAAAACTGCGGAAATGATGACAGAAACGCGTGAATTCGTTAAACAAGGTGCTGCAGATGAAGTAGA
ACTTATTGAAGGAGCTAGAGGCGCAGAATATGAAGGTATGCGAATTCATAGTGTGCGTTTACCAGGACTTGTAGCACATC
AAGAAGTGATTTTTGGAGCAGAGGGACAAGGATTAACAATTCGCCATGACTCTTATGACCGAATTTCCTTTATGTCTGGC
GTGGCACTTTCTGTACGTAAAACAAAAGAACTTGAAACACTTATTTATGGCTTAGAAAATATTTTAGACTAA

Upstream 100 bases:

>100_bases
ACTCACTTGATATTGATATGGAAAAAGCACACGATACGGTCATGGCAAAATTTAAAGAACGCGATAAAGATCGTTGGACA
AAAAAGGAGGAAAAAGCAAA

Downstream 100 bases:

>100_bases
GGATAGGTGAATGAGATGCATATCGCATTAATCGCGCACGATGAAAAGAAAGATTTGATGGTTGGATTTGCAACTGCATA
TAAACATTTGCTCGAACCGC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MRVAVSGFKGRMGHEVVKTVLREADLELVAVLDHEPKEKNINEIVEFSSLDVPVFGNLSEMLEEIKPDCVVDFTTPKVGY
SNTKTILEHGVRAVVGTTGFTPEQISELRSIAESKKIGALIAPNFAVGAVLMMQFAQKAAKYFPNVEIIELHHDNKLDAP
SGTAVKTAEMMTETREFVKQGAADEVELIEGARGAEYEGMRIHSVRLPGLVAHQEVIFGAEGQGLTIRHDSYDRISFMSG
VALSVRKTKELETLIYGLENILD

Sequences:

>Translated_263_residues
MRVAVSGFKGRMGHEVVKTVLREADLELVAVLDHEPKEKNINEIVEFSSLDVPVFGNLSEMLEEIKPDCVVDFTTPKVGY
SNTKTILEHGVRAVVGTTGFTPEQISELRSIAESKKIGALIAPNFAVGAVLMMQFAQKAAKYFPNVEIIELHHDNKLDAP
SGTAVKTAEMMTETREFVKQGAADEVELIEGARGAEYEGMRIHSVRLPGLVAHQEVIFGAEGQGLTIRHDSYDRISFMSG
VALSVRKTKELETLIYGLENILD
>Mature_263_residues
MRVAVSGFKGRMGHEVVKTVLREADLELVAVLDHEPKEKNINEIVEFSSLDVPVFGNLSEMLEEIKPDCVVDFTTPKVGY
SNTKTILEHGVRAVVGTTGFTPEQISELRSIAESKKIGALIAPNFAVGAVLMMQFAQKAAKYFPNVEIIELHHDNKLDAP
SGTAVKTAEMMTETREFVKQGAADEVELIEGARGAEYEGMRIHSVRLPGLVAHQEVIFGAEGQGLTIRHDSYDRISFMSG
VALSVRKTKELETLIYGLENILD

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=270, Percent_Identity=28.5185185185185, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28913; Mature: 28913

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVAVSGFKGRMGHEVVKTVLREADLELVAVLDHEPKEKNINEIVEFSSLDVPVFGNLSE
CEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHH
MLEEIKPDCVVDFTTPKVGYSNTKTILEHGVRAVVGTTGFTPEQISELRSIAESKKIGAL
HHHHCCCCEEEEECCCCCCCCCHHHHHHCCHHEEECCCCCCHHHHHHHHHHHHHHHCCEE
IAPNFAVGAVLMMQFAQKAAKYFPNVEIIELHHDNKLDAPSGTAVKTAEMMTETREFVKQ
ECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
GAADEVELIEGARGAEYEGMRIHSVRLPGLVAHQEVIFGAEGQGLTIRHDSYDRISFMSG
CCCCHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHEEECCCCCCEEEECCCCCHHHHHHC
VALSVRKTKELETLIYGLENILD
CHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVAVSGFKGRMGHEVVKTVLREADLELVAVLDHEPKEKNINEIVEFSSLDVPVFGNLSE
CEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCHHH
MLEEIKPDCVVDFTTPKVGYSNTKTILEHGVRAVVGTTGFTPEQISELRSIAESKKIGAL
HHHHCCCCEEEEECCCCCCCCCHHHHHHCCHHEEECCCCCCHHHHHHHHHHHHHHHCCEE
IAPNFAVGAVLMMQFAQKAAKYFPNVEIIELHHDNKLDAPSGTAVKTAEMMTETREFVKQ
ECCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHC
GAADEVELIEGARGAEYEGMRIHSVRLPGLVAHQEVIFGAEGQGLTIRHDSYDRISFMSG
CCCCHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHEEECCCCCCEEEECCCCCHHHHHHC
VALSVRKTKELETLIYGLENILD
CHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]