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The map label for this gene is msrB [H]

Identifier: 226224462

GI number: 226224462

Start: 1920578

End: 1921015

Strand: Reverse

Name: msrB [H]

Synonym: Lm4b_01875

Alternate gene names: 226224462

Gene position: 1921015-1920578 (Counterclockwise)

Preceding gene: 226224463

Following gene: 226224461

Centisome position: 65.95

GC content: 40.41

Gene sequence:

>438_bases
ATGGATGAAAGTAAAAAGAACGAGCGCCTTCAACAACTAACAGATATACAATATAATGTGACCCAAAAAGCGGGTACCGA
ACGCCCATTTCAAAATGAATTTTATGATAATGAGGCAAAAGGCATTTATGTAGATATCGTTTCAGGAAAGCCACTTTTTT
CATCCAATGATCAGTACGATGCTGGCTGTGGTTGGCCGAGCTTTACTAAGCCTATTGATGAAGCAGAAGTTATTGAACAT
CGAGATTTGACCCATGGTATGATTCGGACGGAAGTGAAATCTGCTGATGCTGATTCCCATTTAGGGCATGTTTTTCCAGA
TGGACCACAAGATAAGGGTGGACTTCGCTACTGCATTAACTCCGCAGCGCTCAGATTCATACCTGTGGATAAGTTAGAAG
AAGAAGGCTACCAAGCATATAAGAAAATCTTTGAATAA

Upstream 100 bases:

>100_bases
TCAAGATTTTTACAAGAAAGAAAAAGCGCACTATGAGGGATATCAAGTTGCTTCAGGTCGTGCTGCATTCATAGATGCCA
ACTGGAAAGGGTGAAATCAA

Downstream 100 bases:

>100_bases
ACACATGATGCCAGAAAATGAAATGCGTAGAATAATATCGCGAAATCATTCTCTGGCATTGTTGTGATAAGGAGCGATAC
ACATGTTAAAAATAGCGGTA

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MDESKKNERLQQLTDIQYNVTQKAGTERPFQNEFYDNEAKGIYVDIVSGKPLFSSNDQYDAGCGWPSFTKPIDEAEVIEH
RDLTHGMIRTEVKSADADSHLGHVFPDGPQDKGGLRYCINSAALRFIPVDKLEEEGYQAYKKIFE

Sequences:

>Translated_145_residues
MDESKKNERLQQLTDIQYNVTQKAGTERPFQNEFYDNEAKGIYVDIVSGKPLFSSNDQYDAGCGWPSFTKPIDEAEVIEH
RDLTHGMIRTEVKSADADSHLGHVFPDGPQDKGGLRYCINSAALRFIPVDKLEEEGYQAYKKIFE
>Mature_145_residues
MDESKKNERLQQLTDIQYNVTQKAGTERPFQNEFYDNEAKGIYVDIVSGKPLFSSNDQYDAGCGWPSFTKPIDEAEVIEH
RDLTHGMIRTEVKSADADSHLGHVFPDGPQDKGGLRYCINSAALRFIPVDKLEEEGYQAYKKIFE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=125, Percent_Identity=44.8, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI301336162, Length=125, Percent_Identity=44.8, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI73089054, Length=125, Percent_Identity=44.8, Blast_Score=118, Evalue=2e-27,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=44.8, Blast_Score=117, Evalue=2e-27,
Organism=Homo sapiens, GI117606353, Length=130, Percent_Identity=43.0769230769231, Blast_Score=105, Evalue=2e-23,
Organism=Escherichia coli, GI1788077, Length=133, Percent_Identity=47.3684210526316, Blast_Score=132, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17553450, Length=123, Percent_Identity=43.0894308943089, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI115532676, Length=123, Percent_Identity=43.0894308943089, Blast_Score=111, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319816, Length=133, Percent_Identity=33.0827067669173, Blast_Score=78, Evalue=5e-16,
Organism=Drosophila melanogaster, GI221378664, Length=123, Percent_Identity=48.780487804878, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378662, Length=130, Percent_Identity=46.9230769230769, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45553335, Length=126, Percent_Identity=48.4126984126984, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21356369, Length=126, Percent_Identity=48.4126984126984, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24645799, Length=126, Percent_Identity=48.4126984126984, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24645804, Length=137, Percent_Identity=45.2554744525547, Blast_Score=119, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24645801, Length=137, Percent_Identity=45.2554744525547, Blast_Score=119, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 16493; Mature: 16493

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESKKNERLQQLTDIQYNVTQKAGTERPFQNEFYDNEAKGIYVDIVSGKPLFSSNDQYD
CCCCHHHHHHHHHHHCHHCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
AGCGWPSFTKPIDEAEVIEHRDLTHGMIRTEVKSADADSHLGHVFPDGPQDKGGLRYCIN
CCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
SAALRFIPVDKLEEEGYQAYKKIFE
HHCEEEECHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDESKKNERLQQLTDIQYNVTQKAGTERPFQNEFYDNEAKGIYVDIVSGKPLFSSNDQYD
CCCCHHHHHHHHHHHCHHCCHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
AGCGWPSFTKPIDEAEVIEHRDLTHGMIRTEVKSADADSHLGHVFPDGPQDKGGLRYCIN
CCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHH
SAALRFIPVDKLEEEGYQAYKKIFE
HHCEEEECHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]