Click here to switch to the map view.

The map label for this gene is adeC

Identifier: 226224345

GI number: 226224345

Start: 1797649

End: 1799391

Strand: Reverse

Name: adeC

Synonym: Lm4b_01756

Alternate gene names: 226224345

Gene position: 1799391-1797649 (Counterclockwise)

Preceding gene: 226224346

Following gene: 226224344

Centisome position: 61.78

GC content: 38.9

Gene sequence:

>1743_bases
TTGGTGGAGAATTTAGAACAGCTGCAAGAACGAGTTGCAGTAAGTGATGGACGAGCAAAAGCAGATTTAGTAATAAAAAA
TGGACGAATAATAAATGTGTTTTCAGGAGAAATAATGGACGGAGATATTGCCATCAAAAATGGTTATATTGCTGGTATTG
GCAATTTTCCAGATGCAGAAAAGATAATAGATGCTGCTGGTGCCTTCATTGCACCTGGTTTTATTGATGCACATGTCCAC
GTGGAGAGTGCGATGGTCACACCTGCTGAGTTTGCCCGTGTCTTACTCCCAAATGGTATTACAACGATTGTTACAGACCC
GCATGAAATTGCCAATGTGGCTGGAGAAAAAGGAATTGAATTCATGCTAGAAGATGCCAAAGGAGTACCAATAGACATGT
TTGTCATGCTCCCATCTTCTGTTCCTGCAACGGAAGGCGAACATAATGGCGAAACATTACATGCTGAGAAACTCCATCCG
CTTTATAGACATGAAAAAGTAATCGGCCTTGCAGAAGTGATGGATTTTCCATCTGTAGCAAAAGGAAGTTCGGATATTTT
AACCAAAATTATCGATGCTAAAAAAGAAGGCGGACGAATTGATGGACATGGAGCTGGCTTAACGAGCGCTGATTTGAATA
ATTATTTGGCTGTTGGTATTCGGACAGATCATGAAAGTACTACTGCTAAGGAAGCAACAGACCGCTTACGTGCCGGAATG
TTTGTTATGCTACGCGAGGGAACTGTAGGCCGTGATTTACTTCAAACAATTCCTGCAGTATCTGAAAAAAATAGCCATCG
TTTTTGCTTTTGCACAGATGATAAACTAATTAATGATTTAATTACGGAAGGATCAATTAACTTTAACATTAGACTGGCTA
TCAAAAATGGAATAGACCCAATTACCGCTATCCAAATGGCAACTATTAATGCAGCTAATTGTCATAATTTGCCATACCTT
GGTGCAGTTGCTGCAGGATACCAAGCAGATATTGTTTTTCTAACAGATATAGAAACAGTAGAAATTAGCAAAGTTTTGAA
AAATGGAGAAGTAGTCGTGGATAATGGTGTTCGTCACGAAGCTGCATTTAAGCAACAAGCGGCAGTACCATTTGTATCTC
CACCAATTAATCATCATGTGAGTTTACAAGATTTAGCATTACCTTTGACCAAAGAAACGTGTTATGTAATCGGGATGCAA
CCCAATAGTTTATTTACAGAAAAACGTATCGAACAAGTGGCTATTCATGACGGTAAGTTTGTTCCAACCGTGGAAAATGA
TTTACTCAAAATGGCAGTTGTAGAGCGTCACCATGATACTGGTTGTGTTGGATTAGGCATTGTAAAAGGCTTTGGTTTAA
CAGAAGGCGCAATTGCTACGACTGTCGCGCACGATTCTCATAATATTGTTGCTGTTGGCATTAGTGATGAAGCAATGAAA
GCGGCTATTGATCATATTACTCAAACAGGTGGCGGTATTGCTGTAGTAAATGGAGCTGGTCAGGTACTTCATGATTTAGC
CCTTCCAATCGCTGGATTGCTTAGTGATAAATCATACGAAGAAGTGGAAAACGATTTAGCGGGTCTTTTAAATGCCTTTA
AACAGATTAGTACGGCTGATGGTTTTGATCCATTTTTAACATTGTCATTCTTAACATTACCAGTGATTCCAGAATTAAAA
TTAACCGATCAAGGGTTGTTTGATTTTGCTACGTTTCAAATTATTTCAAATGAAGTAAACTAA

Upstream 100 bases:

>100_bases
ACGGGGGAGAACTTGGAAGCAGTTTTCCCAACCCTTGAAAGCGCAGAAGGTTATTTGCTTGATGAAGGTTTTTTTGAAGC
TTAATTGACGGAGGCGAGTT

Downstream 100 bases:

>100_bases
TTAGTAGCGAGGAGGTGCGCCATGAATTGGTGGAGTTATATAAAAGATAAGCGATTTTTCTTATTGTTTTTTTGTAGTAT
TATGTTTTTTGTAGGCGTGT

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 580; Mature: 580

Protein sequence:

>580_residues
MVENLEQLQERVAVSDGRAKADLVIKNGRIINVFSGEIMDGDIAIKNGYIAGIGNFPDAEKIIDAAGAFIAPGFIDAHVH
VESAMVTPAEFARVLLPNGITTIVTDPHEIANVAGEKGIEFMLEDAKGVPIDMFVMLPSSVPATEGEHNGETLHAEKLHP
LYRHEKVIGLAEVMDFPSVAKGSSDILTKIIDAKKEGGRIDGHGAGLTSADLNNYLAVGIRTDHESTTAKEATDRLRAGM
FVMLREGTVGRDLLQTIPAVSEKNSHRFCFCTDDKLINDLITEGSINFNIRLAIKNGIDPITAIQMATINAANCHNLPYL
GAVAAGYQADIVFLTDIETVEISKVLKNGEVVVDNGVRHEAAFKQQAAVPFVSPPINHHVSLQDLALPLTKETCYVIGMQ
PNSLFTEKRIEQVAIHDGKFVPTVENDLLKMAVVERHHDTGCVGLGIVKGFGLTEGAIATTVAHDSHNIVAVGISDEAMK
AAIDHITQTGGGIAVVNGAGQVLHDLALPIAGLLSDKSYEEVENDLAGLLNAFKQISTADGFDPFLTLSFLTLPVIPELK
LTDQGLFDFATFQIISNEVN

Sequences:

>Translated_580_residues
MVENLEQLQERVAVSDGRAKADLVIKNGRIINVFSGEIMDGDIAIKNGYIAGIGNFPDAEKIIDAAGAFIAPGFIDAHVH
VESAMVTPAEFARVLLPNGITTIVTDPHEIANVAGEKGIEFMLEDAKGVPIDMFVMLPSSVPATEGEHNGETLHAEKLHP
LYRHEKVIGLAEVMDFPSVAKGSSDILTKIIDAKKEGGRIDGHGAGLTSADLNNYLAVGIRTDHESTTAKEATDRLRAGM
FVMLREGTVGRDLLQTIPAVSEKNSHRFCFCTDDKLINDLITEGSINFNIRLAIKNGIDPITAIQMATINAANCHNLPYL
GAVAAGYQADIVFLTDIETVEISKVLKNGEVVVDNGVRHEAAFKQQAAVPFVSPPINHHVSLQDLALPLTKETCYVIGMQ
PNSLFTEKRIEQVAIHDGKFVPTVENDLLKMAVVERHHDTGCVGLGIVKGFGLTEGAIATTVAHDSHNIVAVGISDEAMK
AAIDHITQTGGGIAVVNGAGQVLHDLALPIAGLLSDKSYEEVENDLAGLLNAFKQISTADGFDPFLTLSFLTLPVIPELK
LTDQGLFDFATFQIISNEVN
>Mature_580_residues
MVENLEQLQERVAVSDGRAKADLVIKNGRIINVFSGEIMDGDIAIKNGYIAGIGNFPDAEKIIDAAGAFIAPGFIDAHVH
VESAMVTPAEFARVLLPNGITTIVTDPHEIANVAGEKGIEFMLEDAKGVPIDMFVMLPSSVPATEGEHNGETLHAEKLHP
LYRHEKVIGLAEVMDFPSVAKGSSDILTKIIDAKKEGGRIDGHGAGLTSADLNNYLAVGIRTDHESTTAKEATDRLRAGM
FVMLREGTVGRDLLQTIPAVSEKNSHRFCFCTDDKLINDLITEGSINFNIRLAIKNGIDPITAIQMATINAANCHNLPYL
GAVAAGYQADIVFLTDIETVEISKVLKNGEVVVDNGVRHEAAFKQQAAVPFVSPPINHHVSLQDLALPLTKETCYVIGMQ
PNSLFTEKRIEQVAIHDGKFVPTVENDLLKMAVVERHHDTGCVGLGIVKGFGLTEGAIATTVAHDSHNIVAVGISDEAMK
AAIDHITQTGGGIAVVNGAGQVLHDLALPIAGLLSDKSYEEVENDLAGLLNAFKQISTADGFDPFLTLSFLTLPVIPELK
LTDQGLFDFATFQIISNEVN

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=580, Percent_Identity=39.3103448275862, Blast_Score=355, Evalue=4e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 62164; Mature: 62164

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVENLEQLQERVAVSDGRAKADLVIKNGRIINVFSGEIMDGDIAIKNGYIAGIGNFPDAE
CCCCHHHHHHHHHHCCCCCEEEEEEECCEEEEEECCCEECCCEEEECCEEEECCCCCCHH
KIIDAAGAFIAPGFIDAHVHVESAMVTPAEFARVLLPNGITTIVTDPHEIANVAGEKGIE
HHHHHCCCEECCCEEEEEEEECCEECCHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCE
FMLEDAKGVPIDMFVMLPSSVPATEGEHNGETLHAEKLHPLYRHEKVIGLAEVMDFPSVA
EEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHCCCCCC
KGSSDILTKIIDAKKEGGRIDGHGAGLTSADLNNYLAVGIRTDHESTTAKEATDRLRAGM
CCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCE
FVMLREGTVGRDLLQTIPAVSEKNSHRFCFCTDDKLINDLITEGSINFNIRLAIKNGIDP
EEEEECCCCCHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEEEEECCCCC
ITAIQMATINAANCHNLPYLGAVAAGYQADIVFLTDIETVEISKVLKNGEVVVDNGVRHE
CCEEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCEEEECCCCHH
AAFKQQAAVPFVSPPINHHVSLQDLALPLTKETCYVIGMQPNSLFTEKRIEQVAIHDGKF
HHHHHHCCCCCCCCCCCCCEEHHHHCCEEECCCEEEEEECCCCHHHHHHHHHHEECCCCC
VPTVENDLLKMAVVERHHDTGCVGLGIVKGFGLTEGAIATTVAHDSHNIVAVGISDEAMK
CCCHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCEEEEEEECCCCEEEEECCHHHHH
AAIDHITQTGGGIAVVNGAGQVLHDLALPIAGLLSDKSYEEVENDLAGLLNAFKQISTAD
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
GFDPFLTLSFLTLPVIPELKLTDQGLFDFATFQIISNEVN
CCCHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MVENLEQLQERVAVSDGRAKADLVIKNGRIINVFSGEIMDGDIAIKNGYIAGIGNFPDAE
CCCCHHHHHHHHHHCCCCCEEEEEEECCEEEEEECCCEECCCEEEECCEEEECCCCCCHH
KIIDAAGAFIAPGFIDAHVHVESAMVTPAEFARVLLPNGITTIVTDPHEIANVAGEKGIE
HHHHHCCCEECCCEEEEEEEECCEECCHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCE
FMLEDAKGVPIDMFVMLPSSVPATEGEHNGETLHAEKLHPLYRHEKVIGLAEVMDFPSVA
EEEECCCCCCEEEEEEECCCCCCCCCCCCCCEEEHHHCCHHHHHHHHHHHHHHHCCCCCC
KGSSDILTKIIDAKKEGGRIDGHGAGLTSADLNNYLAVGIRTDHESTTAKEATDRLRAGM
CCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHCCE
FVMLREGTVGRDLLQTIPAVSEKNSHRFCFCTDDKLINDLITEGSINFNIRLAIKNGIDP
EEEEECCCCCHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHCCCCEEEEEEEEECCCCC
ITAIQMATINAANCHNLPYLGAVAAGYQADIVFLTDIETVEISKVLKNGEVVVDNGVRHE
CCEEEEEEECCCCCCCCCCHHHHHCCCCCCEEEEECCCHHHHHHHHHCCCEEEECCCCHH
AAFKQQAAVPFVSPPINHHVSLQDLALPLTKETCYVIGMQPNSLFTEKRIEQVAIHDGKF
HHHHHHCCCCCCCCCCCCCEEHHHHCCEEECCCEEEEEECCCCHHHHHHHHHHEECCCCC
VPTVENDLLKMAVVERHHDTGCVGLGIVKGFGLTEGAIATTVAHDSHNIVAVGISDEAMK
CCCHHHHHHHHHHHHHCCCCCEEEEHHHHCCCCCCCCEEEEEEECCCCEEEEECCHHHHH
AAIDHITQTGGGIAVVNGAGQVLHDLALPIAGLLSDKSYEEVENDLAGLLNAFKQISTAD
HHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
GFDPFLTLSFLTLPVIPELKLTDQGLFDFATFQIISNEVN
CCCHHHHHHHHHHCCCCCCEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]