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The map label for this gene is inlA [H]

Identifier: 226223738

GI number: 226223738

Start: 1152798

End: 1154342

Strand: Direct

Name: inlA [H]

Synonym: Lm4b_01142

Alternate gene names: 226223738

Gene position: 1152798-1154342 (Clockwise)

Preceding gene: 226223737

Following gene: 226223742

Centisome position: 39.58

GC content: 38.19

Gene sequence:

>1545_bases
ATGAAAAAAACTATCAAGATTACAACCAGTTTACTTTTGAGCTTTGCTTGTGTATTTAGCATGGGGGATTTTACTAAGCC
GCACACAGTCGAAGCTGAAACAGTCTATTCGCTTACAAATCCAAGTCCAATTAATGAAATTTTTCCTGATCCAAAGCTCG
CACAAGTTGTGGCGGATTGGTTAAAGCTTCCATCTGCGACTAGCATGGTTACGCAAAGCCAATTGAATACAATTAAATCT
TTGCACTTTGATTCAAAAGGTGTTCAAAGTCTTGAAGGAGTAGAATATTTAAAAAATCTCACGCAAGTATTTGGCTATGG
TAATCAAGTGAGTGATCTAGGACCATTAAGTAATTTAACGCAACTTGAAATCATCCAGATGCCAAGAAACCAAATAAGTG
ATTTAACACCCATTTCGAATTTGACAGCATTAATGTCACTTGATTTTGAATTTAATAACTTACAAACGATTGAACCGATA
AAAAATTTAACGAACATGTTAGAACTGAATGTTAGCGCAAATCCTATTTCGGATATTAGTGCCGTTAAAAACATGACACA
ACTGGAATTTTTGACCATAAGAGACTGTGAGGTAAGTGATTTATCGTCAGTTGAAAATCTGTCTAATATGCTGATGTTTT
GGGCAGGTAGAAATAATATTAGTGATATTACGCCGCTCAAAAATATGCCCAAACTGCTTGGTTTAAGTTTATTTGGGAAT
CAAATCAAGGATGTGAGTGTGGTTAAAAATTTTACTAGCCTTGAAGATTTCGATATAAAAGCGAATCAGGTGAGGGATAT
TAGTAGCTTAGCAACGTCAACTACACTCGAGACATTAACTCTTAGTTTCAACCAAATAATTGATATTTCACCCCTGAAAA
ATTTGACCAATTTAACTAGGTTAGAACTTGAGAACCAAACGCGTGTATTAGATGCGGTTGAGGTAGATAATCCATTGATT
TTACCCGCTCCAGTAATGGATGAAAATGGCAGCAGAGTACAACCAACAAAAGTAAGTCATGCGGGTATTTATGCAAATGG
CGAGATTACATGGGAAGGGTTGCAAAGTAATTATATTCTAAATTACGAGTATAATTTACCCGTAACAATTGGTTCGTTAA
CAACAACGTATTCTGGTAAAATTACCCAGCCACTGTTGGAGAAGCCTGTTGATCCGATTACTCCGGTAGACCCGGTAGAC
CCGGTAGACCCGGTAGACCCGGTAGACCCGGTAGACCCGGTAGACCCGGTAGACCCGGTAGACCCGGTAGACCCGGTAGA
CCCGGTAGACCCGGTAGATCCGGTAGATCCATTAGACCCAGTCACTCCAGTAAACCCGTCAAATCAGGTAAATTCAATTG
ATCCAGTGAAATCAGTTATTCAAGCTACTGAAACTTTACTGAAACAGACTACTGCAATTAATCCGATAGTAGCTAAAGAG
AATAGAAATTTACCGAAAACAGGGGATAGTGGAATGACTTCTAGTTTATTTAGGGGTTTAATCCTAGCAGTTTCTAGTGT
GATATTATTGCGTAAACGAAAATAA

Upstream 100 bases:

>100_bases
AAGAAAAAAATTTCCTGAAACAAGAAAAATTGCCTCCTTATTCTGTTGATTTGATTATATAAGCAGAGTATTATGTTGAT
TGACAATCAAGGAGGATACT

Downstream 100 bases:

>100_bases
AAAAAGGAATTTGGCTTTTAGTCAAATTCCTTTTCTATACGATTTTTGTGCCTTGGTGAAAGGTGAGTTTCCACGAGCCA
TTTTCGATAATCCAGATGTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 514; Mature: 514

Protein sequence:

>514_residues
MKKTIKITTSLLLSFACVFSMGDFTKPHTVEAETVYSLTNPSPINEIFPDPKLAQVVADWLKLPSATSMVTQSQLNTIKS
LHFDSKGVQSLEGVEYLKNLTQVFGYGNQVSDLGPLSNLTQLEIIQMPRNQISDLTPISNLTALMSLDFEFNNLQTIEPI
KNLTNMLELNVSANPISDISAVKNMTQLEFLTIRDCEVSDLSSVENLSNMLMFWAGRNNISDITPLKNMPKLLGLSLFGN
QIKDVSVVKNFTSLEDFDIKANQVRDISSLATSTTLETLTLSFNQIIDISPLKNLTNLTRLELENQTRVLDAVEVDNPLI
LPAPVMDENGSRVQPTKVSHAGIYANGEITWEGLQSNYILNYEYNLPVTIGSLTTTYSGKITQPLLEKPVDPITPVDPVD
PVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPLDPVTPVNPSNQVNSIDPVKSVIQATETLLKQTTAINPIVAKE
NRNLPKTGDSGMTSSLFRGLILAVSSVILLRKRK

Sequences:

>Translated_514_residues
MKKTIKITTSLLLSFACVFSMGDFTKPHTVEAETVYSLTNPSPINEIFPDPKLAQVVADWLKLPSATSMVTQSQLNTIKS
LHFDSKGVQSLEGVEYLKNLTQVFGYGNQVSDLGPLSNLTQLEIIQMPRNQISDLTPISNLTALMSLDFEFNNLQTIEPI
KNLTNMLELNVSANPISDISAVKNMTQLEFLTIRDCEVSDLSSVENLSNMLMFWAGRNNISDITPLKNMPKLLGLSLFGN
QIKDVSVVKNFTSLEDFDIKANQVRDISSLATSTTLETLTLSFNQIIDISPLKNLTNLTRLELENQTRVLDAVEVDNPLI
LPAPVMDENGSRVQPTKVSHAGIYANGEITWEGLQSNYILNYEYNLPVTIGSLTTTYSGKITQPLLEKPVDPITPVDPVD
PVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPLDPVTPVNPSNQVNSIDPVKSVIQATETLLKQTTAINPIVAKE
NRNLPKTGDSGMTSSLFRGLILAVSSVILLRKRK
>Mature_514_residues
MKKTIKITTSLLLSFACVFSMGDFTKPHTVEAETVYSLTNPSPINEIFPDPKLAQVVADWLKLPSATSMVTQSQLNTIKS
LHFDSKGVQSLEGVEYLKNLTQVFGYGNQVSDLGPLSNLTQLEIIQMPRNQISDLTPISNLTALMSLDFEFNNLQTIEPI
KNLTNMLELNVSANPISDISAVKNMTQLEFLTIRDCEVSDLSSVENLSNMLMFWAGRNNISDITPLKNMPKLLGLSLFGN
QIKDVSVVKNFTSLEDFDIKANQVRDISSLATSTTLETLTLSFNQIIDISPLKNLTNLTRLELENQTRVLDAVEVDNPLI
LPAPVMDENGSRVQPTKVSHAGIYANGEITWEGLQSNYILNYEYNLPVTIGSLTTTYSGKITQPLLEKPVDPITPVDPVD
PVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPVDPLDPVTPVNPSNQVNSIDPVKSVIQATETLLKQTTAINPIVAKE
NRNLPKTGDSGMTSSLFRGLILAVSSVILLRKRK

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=235, Percent_Identity=26.8085106382979, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI21389483, Length=242, Percent_Identity=28.5123966942149, Blast_Score=76, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17554124, Length=183, Percent_Identity=27.3224043715847, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17536161, Length=217, Percent_Identity=28.110599078341, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17531555, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322655, Length=243, Percent_Identity=27.9835390946502, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21358617, Length=211, Percent_Identity=27.4881516587678, Blast_Score=83, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 56385; Mature: 56385

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTIKITTSLLLSFACVFSMGDFTKPHTVEAETVYSLTNPSPINEIFPDPKLAQVVADW
CCCEEHHHHHHHHHHHHHHHCCCCCCCCEECHHHEEECCCCCCCHHHCCCCHHHHHHHHH
LKLPSATSMVTQSQLNTIKSLHFDSKGVQSLEGVEYLKNLTQVFGYGNQVSDLGPLSNLT
HHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QLEIIQMPRNQISDLTPISNLTALMSLDFEFNNLQTIEPIKNLTNMLELNVSANPISDIS
CHHEECCCHHHHHCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHEEECCCCCCCHHHH
AVKNMTQLEFLTIRDCEVSDLSSVENLSNMLMFWAGRNNISDITPLKNMPKLLGLSLFGN
HHHHHHHEEEEEEECCCCHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
QIKDVSVVKNFTSLEDFDIKANQVRDISSLATSTTLETLTLSFNQIIDISPLKNLTNLTR
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEECHHHEEECCHHHHHHHHHH
LELENQTRVLDAVEVDNPLILPAPVMDENGSRVQPTKVSHAGIYANGEITWEGLQSNYIL
HEECCCHHEEHHEECCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCEEE
NYEYNLPVTIGSLTTTYSGKITQPLLEKPVDPITPVDPVDPVDPVDPVDPVDPVDPVDPV
EEEECCCEEECCCEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DPVDPVDPVDPVDPVDPLDPVTPVNPSNQVNSIDPVKSVIQATETLLKQTTAINPIVAKE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECC
NRNLPKTGDSGMTSSLFRGLILAVSSVILLRKRK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKTIKITTSLLLSFACVFSMGDFTKPHTVEAETVYSLTNPSPINEIFPDPKLAQVVADW
CCCEEHHHHHHHHHHHHHHHCCCCCCCCEECHHHEEECCCCCCCHHHCCCCHHHHHHHHH
LKLPSATSMVTQSQLNTIKSLHFDSKGVQSLEGVEYLKNLTQVFGYGNQVSDLGPLSNLT
HHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
QLEIIQMPRNQISDLTPISNLTALMSLDFEFNNLQTIEPIKNLTNMLELNVSANPISDIS
CHHEECCCHHHHHCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHEEECCCCCCCHHHH
AVKNMTQLEFLTIRDCEVSDLSSVENLSNMLMFWAGRNNISDITPLKNMPKLLGLSLFGN
HHHHHHHEEEEEEECCCCHHHHHHHHHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHCC
QIKDVSVVKNFTSLEDFDIKANQVRDISSLATSTTLETLTLSFNQIIDISPLKNLTNLTR
CHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHEECHHHEEECCHHHHHHHHHH
LELENQTRVLDAVEVDNPLILPAPVMDENGSRVQPTKVSHAGIYANGEITWEGLQSNYIL
HEECCCHHEEHHEECCCCEEECCCCCCCCCCCCCCCCCCCCCEEECCEEEEEECCCCEEE
NYEYNLPVTIGSLTTTYSGKITQPLLEKPVDPITPVDPVDPVDPVDPVDPVDPVDPVDPV
EEEECCCEEECCCEEECCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DPVDPVDPVDPVDPVDPLDPVTPVNPSNQVNSIDPVKSVIQATETLLKQTTAINPIVAKE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEECC
NRNLPKTGDSGMTSSLFRGLILAVSSVILLRKRK
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]