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The map label for this gene is adhR [H]

Identifier: 226223733

GI number: 226223733

Start: 1148315

End: 1148662

Strand: Direct

Name: adhR [H]

Synonym: Lm4b_01136

Alternate gene names: 226223733

Gene position: 1148315-1148662 (Clockwise)

Preceding gene: 226223731

Following gene: 226223734

Centisome position: 39.42

GC content: 33.05

Gene sequence:

>348_bases
ATGTATATTAAAGATTTTGCCATTAAAACGGGGCTTTCGATTGATACGCTTCGATATTACGAGGAAGAAGAATTATTAAT
TCCTGCTAGAAATGAAAAAAATTATCGTGTTTATACAGAAGAAGATTACTGCTGGGTACAGCTTTTACTTAAAATGAAGC
AAACAGGGATGACGATAACAAACATTAAAAATTTTGCTGCATTACAAAAGCAAGGGGACATGACACTTCCAAATCGGATA
AAAATTTTGGATAATCATATGGAAAACTTGTATGAACAACAGAAAGATTTAGCGGAAACGATTTCCTTTGTGGCTAAAAA
AGTGGATGGGTATCGAGAGAAGTTATAA

Upstream 100 bases:

>100_bases
ATATAAATAATTCTTTTTTTCTTTTAAATACATTTCTTCTCCTCCTTTGACTATGTTAAGCTTAAGGTATGGAGTATACC
CGATAGCAAGGAGGAACTAG

Downstream 100 bases:

>100_bases
ATACAACAGGAAAGGCGAGTAGAGATGATTAATAATGAGATACGAGAAGTGATCGGATTACATCAAATTAATGAAAATGA
TCAGAAATTGACTGTGGAAA

Product: regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MYIKDFAIKTGLSIDTLRYYEEEELLIPARNEKNYRVYTEEDYCWVQLLLKMKQTGMTITNIKNFAALQKQGDMTLPNRI
KILDNHMENLYEQQKDLAETISFVAKKVDGYREKL

Sequences:

>Translated_115_residues
MYIKDFAIKTGLSIDTLRYYEEEELLIPARNEKNYRVYTEEDYCWVQLLLKMKQTGMTITNIKNFAALQKQGDMTLPNRI
KILDNHMENLYEQQKDLAETISFVAKKVDGYREKL
>Mature_115_residues
MYIKDFAIKTGLSIDTLRYYEEEELLIPARNEKNYRVYTEEDYCWVQLLLKMKQTGMTITNIKNFAALQKQGDMTLPNRI
KILDNHMENLYEQQKDLAETISFVAKKVDGYREKL

Specific function: Transcriptional regulator involved in the response to aldehyde stress. Binds to the promoter region of the adhA-yraA operon, the yraC and its own promoter region; binding is unchanged in the presence of aldehydes [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 13678; Mature: 13678

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYIKDFAIKTGLSIDTLRYYEEEELLIPARNEKNYRVYTEEDYCWVQLLLKMKQTGMTIT
CCCCCCHHHCCCCHHHHHHCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHCCCHH
NIKNFAALQKQGDMTLPNRIKILDNHMENLYEQQKDLAETISFVAKKVDGYREKL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MYIKDFAIKTGLSIDTLRYYEEEELLIPARNEKNYRVYTEEDYCWVQLLLKMKQTGMTIT
CCCCCCHHHCCCCHHHHHHCCCCCEEEECCCCCCEEEEECCCHHHHHHHHHHHHHCCCHH
NIKNFAALQKQGDMTLPNRIKILDNHMENLYEQQKDLAETISFVAKKVDGYREKL
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141695; 9384377 [H]