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The map label for this gene is moaE [H]

Identifier: 226223662

GI number: 226223662

Start: 1074184

End: 1074606

Strand: Direct

Name: moaE [H]

Synonym: Lm4b_01064

Alternate gene names: 226223662

Gene position: 1074184-1074606 (Clockwise)

Preceding gene: 226223661

Following gene: 226223663

Centisome position: 36.88

GC content: 39.48

Gene sequence:

>423_bases
ATGAAATATGTAGCTTTGCAACATGAAAAAATCGAAATAGGACCACTTTCTGATAAACTAATCAATAAAAATCACGGTGG
GACTAATCTTTTTGTTGGTACAATTCGAGAATGGACGGGTGACATTCAAACAGAAGAAATTCGTTACACATCGTACGAGG
AAATGGCGCTCAAAGAACTAAATAAATTAGCGGTAGAAGTAGAAACAAAGTGGGGGGCGGATGTTGTTATCGTCCACCGA
CTAGGACTTTTACAAATAACAGATGTCGCTGTGCTCATCGGTGTATCAACACCACACAGAGCCGCTTGCTACGAGGGATC
CAGATATATTATTGAACGTTTAAAAGAACGGGTACCTATATGGAAAGAAGAAAAAGATGTCGATAAAACAAGGTGGGGTG
GCATAGATGCTAACAACAGTTAA

Upstream 100 bases:

>100_bases
TTGCGACGCATAATCCAGCGTTAAAAAATGAAGCTATTTTCATCGGCGAAGAAAAAGCTTTAACCCTTTTTGCAGAAACG
TTAATCAAGGAGTTTTTAAA

Downstream 100 bases:

>100_bases
ATTTTTCGCTTTTTTAGCTGATAAGACACATAAAACGGAAGTGAAATTGAATTTGCAGCAATGCCAGACAGTTGGCGAGG
TTCGAGAAGTTATTAGTAGT

Product: molybdopterin converting factor, subunit 2

Products: NA

Alternate protein names: MPT synthase subunit 2; Molybdenum cofactor biosynthesis protein E; Molybdopterin-converting factor large subunit; Molybdopterin-converting factor subunit 2 [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MKYVALQHEKIEIGPLSDKLINKNHGGTNLFVGTIREWTGDIQTEEIRYTSYEEMALKELNKLAVEVETKWGADVVIVHR
LGLLQITDVAVLIGVSTPHRAACYEGSRYIIERLKERVPIWKEEKDVDKTRWGGIDANNS

Sequences:

>Translated_140_residues
MKYVALQHEKIEIGPLSDKLINKNHGGTNLFVGTIREWTGDIQTEEIRYTSYEEMALKELNKLAVEVETKWGADVVIVHR
LGLLQITDVAVLIGVSTPHRAACYEGSRYIIERLKERVPIWKEEKDVDKTRWGGIDANNS
>Mature_140_residues
MKYVALQHEKIEIGPLSDKLINKNHGGTNLFVGTIREWTGDIQTEEIRYTSYEEMALKELNKLAVEVETKWGADVVIVHR
LGLLQITDVAVLIGVSTPHRAACYEGSRYIIERLKERVPIWKEEKDVDKTRWGGIDANNS

Specific function: Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by moaD [H]

COG id: COG0314

COG function: function code H; Molybdopterin converting factor, large subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaE family [H]

Homologues:

Organism=Homo sapiens, GI4758732, Length=132, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1787003, Length=108, Percent_Identity=29.6296296296296, Blast_Score=62, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356259, Length=126, Percent_Identity=36.5079365079365, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003448 [H]

Pfam domain/function: PF02391 MoaE [H]

EC number: NA

Molecular weight: Translated: 15962; Mature: 15962

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVALQHEKIEIGPLSDKLINKNHGGTNLFVGTIREWTGDIQTEEIRYTSYEEMALKEL
CCEEECCCCEEEECCCCHHHHCCCCCCCEEEEEEHHHHCCCCCCCEEECCCHHHHHHHHH
NKLAVEVETKWGADVVIVHRLGLLQITDVAVLIGVSTPHRAACYEGSRYIIERLKERVPI
HHHEEEEECCCCCCEEEEECCCCEEEEEEEEEEECCCCCCHHHCCCCHHHHHHHHHHCCC
WKEEKDVDKTRWGGIDANNS
CCCCCCCCHHHCCCCCCCCC
>Mature Secondary Structure
MKYVALQHEKIEIGPLSDKLINKNHGGTNLFVGTIREWTGDIQTEEIRYTSYEEMALKEL
CCEEECCCCEEEECCCCHHHHCCCCCCCEEEEEEHHHHCCCCCCCEEECCCHHHHHHHHH
NKLAVEVETKWGADVVIVHRLGLLQITDVAVLIGVSTPHRAACYEGSRYIIERLKERVPI
HHHEEEEECCCCCCEEEEECCCCEEEEEEEEEEECCCCCCHHHCCCCHHHHHHHHHHCCC
WKEEKDVDKTRWGGIDANNS
CCCCCCCCHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]