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The map label for this gene is htpX [H]

Identifier: 226223581

GI number: 226223581

Start: 996844

End: 997758

Strand: Direct

Name: htpX [H]

Synonym: Lm4b_00983

Alternate gene names: 226223581

Gene position: 996844-997758 (Clockwise)

Preceding gene: 226223580

Following gene: 226223585

Centisome position: 34.22

GC content: 38.58

Gene sequence:

>915_bases
ATGCTATTTGAACAAATTGCAGCAAATAAGCGAAAAACAATTTTTATTATTCTTGGCTTTTTCATTTTCGTTCTTATGGT
TGGCGCTGCTATAGGTATAATTGTTTGGAATAACTATCTGAATGGGCTCATACTCGCGGCAGTGATTGGTGCATTTTATA
TTTTGATTATGGTAATGAGCAGTTCATCTGTTGTCATGGCGATGAACCATGCGAAAGAAGTTACATCCAAAGATCAAGCG
CCAGTTTTGTGGGATACAGTAGAGAGTATGGCAATGGTTGCTGGTATTCCGATGCCAAAAGTATATATCGTTGAAGATGC
AAGTCCGAACGCATTTGCGACGGGGATTTCTCCTGAAAAAGGAGCCGTGGCGGTTACTAGAGGATTGCTTAATAAATTAG
AACGTTATGAACTTGAGGGCGTTATTGCGCATGAAATTTCTCATATTCGTAATTATGATATTCGATTATCAACGATTGCC
ATTGCGCTAGTAGCTGTTATTGCGATTCTTAGTGATTTAGCTATGCGAATGATTTTCTGGGGAAGCCTAACTGGTGGCAG
AAATAATCGTAAGAGTGACAATAATAACAGTGGCGGGGCACAAGCGATTATCTATATCGTTGCACTCATATTTGTTATTT
TGGCGCCTATTATTGCAACAGCTATCCAATTTGCTTTATCTCGTAATAGAGAGTATTTAGCTGATGCTAGTGCGGTAGAA
TTAACCAGAAATCCTGATGGACTTATCCAAGCTTTACAAAAAATCAGCGGAGATTCGAAAAAAATGGAAGAAGTTAGTGC
TTCTAGTGAGTCCATTTACTTTGCGTCACCTCTAAAGTCTAAAAAAAATAAGCCAGGTCTTTTTGACTCTCATCCGCCAA
TTAGTTCGCGGATTGAACGCTTAGAAAATATGTAA

Upstream 100 bases:

>100_bases
AAACTGCATAACTTTACAGAACGTGACATGCTTTCTATTCCTGAAGTAGAACGCGTTGCACCAAAAGTAGAGTTTTAAGC
CATGAAGGAGAGCGAAAATT

Downstream 100 bases:

>100_bases
AAAAAAAGAAGCAACCCAGGAATGGGGGTGCTTCTTTTTTATAAGTTTCCGATGTATTTCCAGTGAGCCTGGCCATCTGG
AGCATCGATTAATTCTACTT

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLFEQIAANKRKTIFIILGFFIFVLMVGAAIGIIVWNNYLNGLILAAVIGAFYILIMVMSSSSVVMAMNHAKEVTSKDQA
PVLWDTVESMAMVAGIPMPKVYIVEDASPNAFATGISPEKGAVAVTRGLLNKLERYELEGVIAHEISHIRNYDIRLSTIA
IALVAVIAILSDLAMRMIFWGSLTGGRNNRKSDNNNSGGAQAIIYIVALIFVILAPIIATAIQFALSRNREYLADASAVE
LTRNPDGLIQALQKISGDSKKMEEVSASSESIYFASPLKSKKNKPGLFDSHPPISSRIERLENM

Sequences:

>Translated_304_residues
MLFEQIAANKRKTIFIILGFFIFVLMVGAAIGIIVWNNYLNGLILAAVIGAFYILIMVMSSSSVVMAMNHAKEVTSKDQA
PVLWDTVESMAMVAGIPMPKVYIVEDASPNAFATGISPEKGAVAVTRGLLNKLERYELEGVIAHEISHIRNYDIRLSTIA
IALVAVIAILSDLAMRMIFWGSLTGGRNNRKSDNNNSGGAQAIIYIVALIFVILAPIIATAIQFALSRNREYLADASAVE
LTRNPDGLIQALQKISGDSKKMEEVSASSESIYFASPLKSKKNKPGLFDSHPPISSRIERLENM
>Mature_304_residues
MLFEQIAANKRKTIFIILGFFIFVLMVGAAIGIIVWNNYLNGLILAAVIGAFYILIMVMSSSSVVMAMNHAKEVTSKDQA
PVLWDTVESMAMVAGIPMPKVYIVEDASPNAFATGISPEKGAVAVTRGLLNKLERYELEGVIAHEISHIRNYDIRLSTIA
IALVAVIAILSDLAMRMIFWGSLTGGRNNRKSDNNNSGGAQAIIYIVALIFVILAPIIATAIQFALSRNREYLADASAVE
LTRNPDGLIQALQKISGDSKKMEEVSASSESIYFASPLKSKKNKPGLFDSHPPISSRIERLENM

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=221, Percent_Identity=35.2941176470588, Blast_Score=104, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 33119; Mature: 33119

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFEQIAANKRKTIFIILGFFIFVLMVGAAIGIIVWNNYLNGLILAAVIGAFYILIMVMS
CCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSSVVMAMNHAKEVTSKDQAPVLWDTVESMAMVAGIPMPKVYIVEDASPNAFATGISPEK
CCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCC
GAVAVTRGLLNKLERYELEGVIAHEISHIRNYDIRLSTIAIALVAVIAILSDLAMRMIFW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLTGGRNNRKSDNNNSGGAQAIIYIVALIFVILAPIIATAIQFALSRNREYLADASAVE
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHE
LTRNPDGLIQALQKISGDSKKMEEVSASSESIYFASPLKSKKNKPGLFDSHPPISSRIER
ECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCHHCCCCCCCCCCCCCCHHHHHHH
LENM
HHCC
>Mature Secondary Structure
MLFEQIAANKRKTIFIILGFFIFVLMVGAAIGIIVWNNYLNGLILAAVIGAFYILIMVMS
CCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SSSVVMAMNHAKEVTSKDQAPVLWDTVESMAMVAGIPMPKVYIVEDASPNAFATGISPEK
CCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEECCCCCCC
GAVAVTRGLLNKLERYELEGVIAHEISHIRNYDIRLSTIAIALVAVIAILSDLAMRMIFW
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GSLTGGRNNRKSDNNNSGGAQAIIYIVALIFVILAPIIATAIQFALSRNREYLADASAVE
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHE
LTRNPDGLIQALQKISGDSKKMEEVSASSESIYFASPLKSKKNKPGLFDSHPPISSRIER
ECCCCHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCHHCCCCCCCCCCCCCCHHHHHHH
LENM
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]