Click here to switch to the map view.

The map label for this gene is ltaS1 [H]

Identifier: 226223546

GI number: 226223546

Start: 964417

End: 966378

Strand: Reverse

Name: ltaS1 [H]

Synonym: Lm4b_00946

Alternate gene names: 226223546

Gene position: 966378-964417 (Counterclockwise)

Preceding gene: 226223551

Following gene: 226223528

Centisome position: 33.18

GC content: 35.93

Gene sequence:

>1962_bases
ATGAAGGATTGGAAAATAAAAATCCAAACGTTTTTAAGCAAGAATTATGGATTTTTTGTTCTAGCCGTCATTCTTTATTG
GCTAAAAACGTATATTGCATATCAACTTGAATTTAAACTTGGCATAGAAAATCTGATGCAGCAAATTTTGCTGTTCATTA
ATCCATTAAGTGGGGCCATTTTCTTTATGGGTCTTGCGCTCTTTGCTAAGGGACGTCGTTCATTCATTTGGATTATCGTC
ATTGACTTTTTAATGAGTTTTATTCTTTACGCAAATATTGTATATTATCGATTCTTTAGTGATTTCATTACACTTCCGAA
TCTAAACGCAAAACAAATGCAAAACATGGGCGACATGGGAAGTAGTATCACAGCGTTACTCAGCTGGCACGATATTATTT
ACTTCGCGGATATTATCATTTTAATTGCACTACTTGCTTTCCGCTTTGTAAAACCAAACAAAACAGCCCGTATTCGTGCA
AGAAAAGTAGTTGGGGTTCTGACGCTTGGTATCGCAATGTTCTTTGGAAACTTGGGACTTGCAGAAATTGATCGTCCACA
ACTTCTAACAAGAACGTTTGATAGAAATTATATTGTTAAATATCTTGGTATGACTAACTATCAAATCTATGACGCAGTGA
AAAGTACCGAATCATCCACACAGCGTGCACTTGCTGATAGTAGTGATGTTACAGAAGTCTTAAACTATACCAAATCCAAA
TATGCCGCGCCAAATCCGGAATATTTTGGTAAAGCAAAAGGCAAAAACGTCATTTATATCCATTTAGAGAGTTTCCAACA
ATTCCTAGTAAATTACAAATTAAATGGAGAAGAAGTAACGCCGTTTATTAACTCTTTCTTTAAAGACCAAAATACACTAA
GCTTTACAAACTTCTTCCACCAAACAGGTCAAGGTAAAACAGCTGACTCCGAAATGTTACTTGAGAACTCGCTTTACGGC
TTGCCTCAAGGTTCTGCCTTTACAACTAAAGGGCAAAACACTTATGAATCTGCATCTGCTATTTTAGGCCAACAAGGCTA
TACAAGTGCTGTATTCCACGGTAACTATAAGAGCTTCTGGAATCGTGATGAAATTTATAAACAATTTGGTTACGATAATT
TCTTTGATGCTAGTTACTACGATATGAACGAAGCAGATGTTTCTAACTACGGACTTAAAGATAAACCATTCTTTAAGGAA
TCCGAAGAATATCTATCGTCATTACAACAACCGTTCTACACGAAATTTATTACGCTTACGAACCACTTCCCTTATCCAAT
TGATGAGAAAGATGCTTCGATTGCTCCGGCAACAACAGGCGATTCATCTGTAGATACGTATTTCCAAACAGCTCGTTATT
TAGACGAATCTGTGAAGAGCTTTGTTGATTACTTGAAGAAATCTGGTCTTTACGATAACTCTGTCATTATCATGTACGGT
GACCATTATGGTATTTCCGACAACCATGAAGAAGCAATGACAAAAATTCTTGGTAAAGATTACAACACTTTTGAAAATGC
CCAAGCGCAGCGTGTTCCTTTAATGATTCACGTTCCTGGTGTTCAAGGTGGCGTTCAAGAACAATACGGTGGTCAAGTTG
ACTTACTTCCGACATTACTTCACTTACTTGGTGTTGATAATAAAGAGTACTTGCAATTTGGTACAGATTTACTTTCTAAA
GACCATAAACAACTTGTTCCATTCCGAAATGGTGATTATATAACTCCTACCTATTCAATGATTGGTGGTAACATGTATAA
TCAACAAACTGGGGAACCAATTGCTACGGAAACAAAAGAAATGAAAGAAACAAAAGAAAAAGTAGCAAAAGAATTAGAGC
TTTCAGATTCTGTACTACAAGGTGACTTGTTACGTTTCTATGCTCCTGATGGTTTCAAAAAAGTGGATCCAAGTAAATAC
AATTACAATAAGAAAAAATCAACTGATTCATCCGATAAATGA

Upstream 100 bases:

>100_bases
GGTGCTGTATGAAAATGTTTCTTGTTACATAATACAGCTTCTTTTTTTCATTTCAAAATAACAATTAAAACGAGTAAATA
GTGTGTAGGAGAGGTGTTTC

Downstream 100 bases:

>100_bases
GAAAAAGAGTCCAGAATATCTGGACTCTTTTTTACTTACCTAAACCTCTCATAATATACGCCACCGTATCATCAATTTCT
TTGGCATCATCCCACTCCAC

Product: hypothetical protein

Products: NA

Alternate protein names: LTA synthase 1; Polyglycerol phosphate synthase 1 [H]

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MKDWKIKIQTFLSKNYGFFVLAVILYWLKTYIAYQLEFKLGIENLMQQILLFINPLSGAIFFMGLALFAKGRRSFIWIIV
IDFLMSFILYANIVYYRFFSDFITLPNLNAKQMQNMGDMGSSITALLSWHDIIYFADIIILIALLAFRFVKPNKTARIRA
RKVVGVLTLGIAMFFGNLGLAEIDRPQLLTRTFDRNYIVKYLGMTNYQIYDAVKSTESSTQRALADSSDVTEVLNYTKSK
YAAPNPEYFGKAKGKNVIYIHLESFQQFLVNYKLNGEEVTPFINSFFKDQNTLSFTNFFHQTGQGKTADSEMLLENSLYG
LPQGSAFTTKGQNTYESASAILGQQGYTSAVFHGNYKSFWNRDEIYKQFGYDNFFDASYYDMNEADVSNYGLKDKPFFKE
SEEYLSSLQQPFYTKFITLTNHFPYPIDEKDASIAPATTGDSSVDTYFQTARYLDESVKSFVDYLKKSGLYDNSVIIMYG
DHYGISDNHEEAMTKILGKDYNTFENAQAQRVPLMIHVPGVQGGVQEQYGGQVDLLPTLLHLLGVDNKEYLQFGTDLLSK
DHKQLVPFRNGDYITPTYSMIGGNMYNQQTGEPIATETKEMKETKEKVAKELELSDSVLQGDLLRFYAPDGFKKVDPSKY
NYNKKKSTDSSDK

Sequences:

>Translated_653_residues
MKDWKIKIQTFLSKNYGFFVLAVILYWLKTYIAYQLEFKLGIENLMQQILLFINPLSGAIFFMGLALFAKGRRSFIWIIV
IDFLMSFILYANIVYYRFFSDFITLPNLNAKQMQNMGDMGSSITALLSWHDIIYFADIIILIALLAFRFVKPNKTARIRA
RKVVGVLTLGIAMFFGNLGLAEIDRPQLLTRTFDRNYIVKYLGMTNYQIYDAVKSTESSTQRALADSSDVTEVLNYTKSK
YAAPNPEYFGKAKGKNVIYIHLESFQQFLVNYKLNGEEVTPFINSFFKDQNTLSFTNFFHQTGQGKTADSEMLLENSLYG
LPQGSAFTTKGQNTYESASAILGQQGYTSAVFHGNYKSFWNRDEIYKQFGYDNFFDASYYDMNEADVSNYGLKDKPFFKE
SEEYLSSLQQPFYTKFITLTNHFPYPIDEKDASIAPATTGDSSVDTYFQTARYLDESVKSFVDYLKKSGLYDNSVIIMYG
DHYGISDNHEEAMTKILGKDYNTFENAQAQRVPLMIHVPGVQGGVQEQYGGQVDLLPTLLHLLGVDNKEYLQFGTDLLSK
DHKQLVPFRNGDYITPTYSMIGGNMYNQQTGEPIATETKEMKETKEKVAKELELSDSVLQGDLLRFYAPDGFKKVDPSKY
NYNKKKSTDSSDK
>Mature_653_residues
MKDWKIKIQTFLSKNYGFFVLAVILYWLKTYIAYQLEFKLGIENLMQQILLFINPLSGAIFFMGLALFAKGRRSFIWIIV
IDFLMSFILYANIVYYRFFSDFITLPNLNAKQMQNMGDMGSSITALLSWHDIIYFADIIILIALLAFRFVKPNKTARIRA
RKVVGVLTLGIAMFFGNLGLAEIDRPQLLTRTFDRNYIVKYLGMTNYQIYDAVKSTESSTQRALADSSDVTEVLNYTKSK
YAAPNPEYFGKAKGKNVIYIHLESFQQFLVNYKLNGEEVTPFINSFFKDQNTLSFTNFFHQTGQGKTADSEMLLENSLYG
LPQGSAFTTKGQNTYESASAILGQQGYTSAVFHGNYKSFWNRDEIYKQFGYDNFFDASYYDMNEADVSNYGLKDKPFFKE
SEEYLSSLQQPFYTKFITLTNHFPYPIDEKDASIAPATTGDSSVDTYFQTARYLDESVKSFVDYLKKSGLYDNSVIIMYG
DHYGISDNHEEAMTKILGKDYNTFENAQAQRVPLMIHVPGVQGGVQEQYGGQVDLLPTLLHLLGVDNKEYLQFGTDLLSK
DHKQLVPFRNGDYITPTYSMIGGNMYNQQTGEPIATETKEMKETKEKVAKELELSDSVLQGDLLRFYAPDGFKKVDPSKY
NYNKKKSTDSSDK

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate [H]

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase 1:Secreted. Note=The secretion into the extracellular medium is dependent on secA and ffh [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 74709; Mature: 74709

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDWKIKIQTFLSKNYGFFVLAVILYWLKTYIAYQLEFKLGIENLMQQILLFINPLSGAI
CCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHH
FFMGLALFAKGRRSFIWIIVIDFLMSFILYANIVYYRFFSDFITLPNLNAKQMQNMGDMG
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
SSITALLSWHDIIYFADIIILIALLAFRFVKPNKTARIRARKVVGVLTLGIAMFFGNLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AEIDRPQLLTRTFDRNYIVKYLGMTNYQIYDAVKSTESSTQRALADSSDVTEVLNYTKSK
CCCCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YAAPNPEYFGKAKGKNVIYIHLESFQQFLVNYKLNGEEVTPFINSFFKDQNTLSFTNFFH
CCCCCCHHCCCCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
QTGQGKTADSEMLLENSLYGLPQGSAFTTKGQNTYESASAILGQQGYTSAVFHGNYKSFW
HCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCEEEEECCHHHHC
NRDEIYKQFGYDNFFDASYYDMNEADVSNYGLKDKPFFKESEEYLSSLQQPFYTKFITLT
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHEEEE
NHFPYPIDEKDASIAPATTGDSSVDTYFQTARYLDESVKSFVDYLKKSGLYDNSVIIMYG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
DHYGISDNHEEAMTKILGKDYNTFENAQAQRVPLMIHVPGVQGGVQEQYGGQVDLLPTLL
CCCCCCCCHHHHHHHHHCCCCCCHHCCCHHCCCEEEECCCCCCCCHHHHCCCEEHHHHHH
HLLGVDNKEYLQFGTDLLSKDHKQLVPFRNGDYITPTYSMIGGNMYNQQTGEPIATETKE
HHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHH
MKETKEKVAKELELSDSVLQGDLLRFYAPDGFKKVDPSKYNYNKKKSTDSSDK
HHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKDWKIKIQTFLSKNYGFFVLAVILYWLKTYIAYQLEFKLGIENLMQQILLFINPLSGAI
CCCCEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHH
FFMGLALFAKGRRSFIWIIVIDFLMSFILYANIVYYRFFSDFITLPNLNAKQMQNMGDMG
HHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCC
SSITALLSWHDIIYFADIIILIALLAFRFVKPNKTARIRARKVVGVLTLGIAMFFGNLGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
AEIDRPQLLTRTFDRNYIVKYLGMTNYQIYDAVKSTESSTQRALADSSDVTEVLNYTKSK
CCCCCHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
YAAPNPEYFGKAKGKNVIYIHLESFQQFLVNYKLNGEEVTPFINSFFKDQNTLSFTNFFH
CCCCCCHHCCCCCCCCEEEEEHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHH
QTGQGKTADSEMLLENSLYGLPQGSAFTTKGQNTYESASAILGQQGYTSAVFHGNYKSFW
HCCCCCCCCHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCEEEEECCHHHHC
NRDEIYKQFGYDNFFDASYYDMNEADVSNYGLKDKPFFKESEEYLSSLQQPFYTKFITLT
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHEEEE
NHFPYPIDEKDASIAPATTGDSSVDTYFQTARYLDESVKSFVDYLKKSGLYDNSVIIMYG
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
DHYGISDNHEEAMTKILGKDYNTFENAQAQRVPLMIHVPGVQGGVQEQYGGQVDLLPTLL
CCCCCCCCHHHHHHHHHCCCCCCHHCCCHHCCCEEEECCCCCCCCHHHHCCCEEHHHHHH
HLLGVDNKEYLQFGTDLLSKDHKQLVPFRNGDYITPTYSMIGGNMYNQQTGEPIATETKE
HHHCCCCHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHH
MKETKEKVAKELELSDSVLQGDLLRFYAPDGFKKVDPSKYNYNKKKSTDSSDK
HHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377; 10658653 [H]