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The map label for this gene is cheA

Identifier: 226223323

GI number: 226223323

Start: 734897

End: 736753

Strand: Direct

Name: cheA

Synonym: Lm4b_00720

Alternate gene names: 226223323

Gene position: 734897-736753 (Clockwise)

Preceding gene: 226223322

Following gene: 226223324

Centisome position: 25.23

GC content: 40.66

Gene sequence:

>1857_bases
ATGACTACAAATATGTTAGACCTGTTTATAGAAGAAGCTTCAGAACATTTACAGGCGCTAAATGATAATCTGTTACAGCT
TGAGAAAGACCCGACGAACGGTCAGTTAGTAAGTGAAATTTTCCGTTCAGCACATACATTTAAAGGGATGTCCGCAACGA
TGGGCTTCCAACAGGTGGCTGATTTAACGCATGCAATGGAAAATGTACTAGATGAGGTACGCAATAATCGATTGGCTGTA
ACAGAACATTTGGTAGACATTATTTTTACATGTACATCTCATTTGGAAACAATGGTTTCGGATATCCAGCACGGCGGACA
AGGCGCGGCGGATATTTCGAAAACCGTAGCTGACTTAGAGGCGCTTTTACATCCAGAACAAGAAACAGATTTAGCGGTAG
AAAAAACGTATCGCATTCAGATTCAAATTGAAGAAGCAGCTATTTTGAAAGCAGTACGGGCGGTAATGTGTTTAGAGCGA
CTTGCAGAAATGGGGATTATTTCAGAAACAACGCCAGACAGAGAAGCGATTGAGCTAGAAGAGTTTGAGCAGTCATTCGA
AGTAGTCCTAGAGTCGGCGCAAACAAAAGAAGAAATCGAAGCGGTTGTTCTAGATATTTCTGAAATCGAAAAAGTGACTG
TGACAGAAGAAGTGGAAGAAGTTCAGGTTATTGAACCAATCAAAAAAGCCGCAAAACAAACAACCAAACGATTAGAAAAT
AAAACCATTCGTGTACAACTTGAAAAAATCGAAAAGCTAATGAACGTTTTTGAAGAAAGCGTCATTGAACGGGCGAGAAT
TGATGAAATCGCAGAAAAAACGAATAACAAAGAATTGATGGAACACTTAGGACGATTCAGTTCCATCTCCAAAGAAATTC
AAAACGGCTTACTAAATATGCGTATGGTGCCAGTGGATAGTGTGTTCAATCGCTTTCCAAAAATGGTGCGCACACTAGCC
AAAGAATTAGGTAAGAAAATCGACTTAGTGATTGAAGGCGCGGATACGGAAGTCGACAAAATCGTCATTGATGAAATTGG
CGACCCACTTGTTCACTTAATCCGTAATTCAGTAGACCACGGTGCGGAAACAGTCGAAGTAAGACGTAAAAATGGGAAAA
ATGAAACCGCCACAATTAATCTAAAAGCTTTCCATAGTGGGAACAATGTCGTGATTGAAATTGCGGATGACGGTGCGGGA
ATCAATAAACGCAAAGTGTTAGAAAAAGCGATTGCGAAAAATGTCGTTACAAGAGCAGAATCAACCAAAATGACGGACGC
GGAAATTTTTGATTTATTATTTGATTCCGGTTTCAGTACCGCGGATCAAGTATCCGATCTTTCTGGCCGAGGCGTGGGAC
TAGATGTTGTCCGTAATACGATTCTCAAAATCGGCGGAAAAATCAGCGTAGAATCAAGTGAAAACGCTGGTTCGACGTTC
CGAATTGAGATTCCGCTGACATTATCGATCATCCAATCGATGCTCGTTGCAACATCAGAACGTCGCTATGCTGTACCGCT
GGCAAACGTGGCCGAAGCCATCACAATTAATCCTGCAGACATTCAACACGTTCACGGCAAAGACTTAATCAACTACCGTG
AAACCATTATCGAAGTACTCGATTTAGGCGAATGCTTCCATGAAACACCTTTGAATGACACGGATGAATTACTATTACTC
GTCGTGAAAAATGCCAAGCGAACTTTTGGACTTATTATTAAAGATATTATCGGTCAACGGGAAATCGTTTTAAAAACACT
TGGTGGCTTTTTCAGCGAAAGTCAGATTGCCTTTTCTGGAGCAACGATTTTAGGCGATGGTCGTGTCGTATTAATTTTAA
ATTTAGAAACATTTTAA

Upstream 100 bases:

>100_bases
AAAAAAGGTGCCAAAGACTTTATCGTAAAACCTTTCCAAGCGGACCGGGTTTTAGAGGCGTTAGAAAAAGCAGCTAAGTA
GAGAAATGGAGGTGGATTGC

Downstream 100 bases:

>100_bases
GGAGGAACCATGATGGAACAAGTATTTCAAGTAGAACTTCCTGAATGGGAACCGAAAGAACCGAGCCAAGAAGGACGCGA
AAAAGGCTCTATCCGCCAAG

Product: two-component sensor histidine kinase CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 618; Mature: 617

Protein sequence:

>618_residues
MTTNMLDLFIEEASEHLQALNDNLLQLEKDPTNGQLVSEIFRSAHTFKGMSATMGFQQVADLTHAMENVLDEVRNNRLAV
TEHLVDIIFTCTSHLETMVSDIQHGGQGAADISKTVADLEALLHPEQETDLAVEKTYRIQIQIEEAAILKAVRAVMCLER
LAEMGIISETTPDREAIELEEFEQSFEVVLESAQTKEEIEAVVLDISEIEKVTVTEEVEEVQVIEPIKKAAKQTTKRLEN
KTIRVQLEKIEKLMNVFEESVIERARIDEIAEKTNNKELMEHLGRFSSISKEIQNGLLNMRMVPVDSVFNRFPKMVRTLA
KELGKKIDLVIEGADTEVDKIVIDEIGDPLVHLIRNSVDHGAETVEVRRKNGKNETATINLKAFHSGNNVVIEIADDGAG
INKRKVLEKAIAKNVVTRAESTKMTDAEIFDLLFDSGFSTADQVSDLSGRGVGLDVVRNTILKIGGKISVESSENAGSTF
RIEIPLTLSIIQSMLVATSERRYAVPLANVAEAITINPADIQHVHGKDLINYRETIIEVLDLGECFHETPLNDTDELLLL
VVKNAKRTFGLIIKDIIGQREIVLKTLGGFFSESQIAFSGATILGDGRVVLILNLETF

Sequences:

>Translated_618_residues
MTTNMLDLFIEEASEHLQALNDNLLQLEKDPTNGQLVSEIFRSAHTFKGMSATMGFQQVADLTHAMENVLDEVRNNRLAV
TEHLVDIIFTCTSHLETMVSDIQHGGQGAADISKTVADLEALLHPEQETDLAVEKTYRIQIQIEEAAILKAVRAVMCLER
LAEMGIISETTPDREAIELEEFEQSFEVVLESAQTKEEIEAVVLDISEIEKVTVTEEVEEVQVIEPIKKAAKQTTKRLEN
KTIRVQLEKIEKLMNVFEESVIERARIDEIAEKTNNKELMEHLGRFSSISKEIQNGLLNMRMVPVDSVFNRFPKMVRTLA
KELGKKIDLVIEGADTEVDKIVIDEIGDPLVHLIRNSVDHGAETVEVRRKNGKNETATINLKAFHSGNNVVIEIADDGAG
INKRKVLEKAIAKNVVTRAESTKMTDAEIFDLLFDSGFSTADQVSDLSGRGVGLDVVRNTILKIGGKISVESSENAGSTF
RIEIPLTLSIIQSMLVATSERRYAVPLANVAEAITINPADIQHVHGKDLINYRETIIEVLDLGECFHETPLNDTDELLLL
VVKNAKRTFGLIIKDIIGQREIVLKTLGGFFSESQIAFSGATILGDGRVVLILNLETF
>Mature_617_residues
TTNMLDLFIEEASEHLQALNDNLLQLEKDPTNGQLVSEIFRSAHTFKGMSATMGFQQVADLTHAMENVLDEVRNNRLAVT
EHLVDIIFTCTSHLETMVSDIQHGGQGAADISKTVADLEALLHPEQETDLAVEKTYRIQIQIEEAAILKAVRAVMCLERL
AEMGIISETTPDREAIELEEFEQSFEVVLESAQTKEEIEAVVLDISEIEKVTVTEEVEEVQVIEPIKKAAKQTTKRLENK
TIRVQLEKIEKLMNVFEESVIERARIDEIAEKTNNKELMEHLGRFSSISKEIQNGLLNMRMVPVDSVFNRFPKMVRTLAK
ELGKKIDLVIEGADTEVDKIVIDEIGDPLVHLIRNSVDHGAETVEVRRKNGKNETATINLKAFHSGNNVVIEIADDGAGI
NKRKVLEKAIAKNVVTRAESTKMTDAEIFDLLFDSGFSTADQVSDLSGRGVGLDVVRNTILKIGGKISVESSENAGSTFR
IEIPLTLSIIQSMLVATSERRYAVPLANVAEAITINPADIQHVHGKDLINYRETIIEVLDLGECFHETPLNDTDELLLLV
VKNAKRTFGLIIKDIIGQREIVLKTLGGFFSESQIAFSGATILGDGRVVLILNLETF

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=639, Percent_Identity=30.3599374021909, Blast_Score=316, Evalue=3e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR010808 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt; PF07194 P2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68656; Mature: 68525

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTNMLDLFIEEASEHLQALNDNLLQLEKDPTNGQLVSEIFRSAHTFKGMSATMGFQQVA
CCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
DLTHAMENVLDEVRNNRLAVTEHLVDIIFTCTSHLETMVSDIQHGGQGAADISKTVADLE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALLHPEQETDLAVEKTYRIQIQIEEAAILKAVRAVMCLERLAEMGIISETTPDREAIELE
HHHCCCCCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
EFEQSFEVVLESAQTKEEIEAVVLDISEIEKVTVTEEVEEVQVIEPIKKAAKQTTKRLEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KTIRVQLEKIEKLMNVFEESVIERARIDEIAEKTNNKELMEHLGRFSSISKEIQNGLLNM
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHCE
RMVPVDSVFNRFPKMVRTLAKELGKKIDLVIEGADTEVDKIVIDEIGDPLVHLIRNSVDH
EECCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHC
GAETVEVRRKNGKNETATINLKAFHSGNNVVIEIADDGAGINKRKVLEKAIAKNVVTRAE
CHHHHHHHHCCCCCCEEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
STKMTDAEIFDLLFDSGFSTADQVSDLSGRGVGLDVVRNTILKIGGKISVESSENAGSTF
CCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEE
RIEIPLTLSIIQSMLVATSERRYAVPLANVAEAITINPADIQHVHGKDLINYRETIIEVL
EEEECHHHHHHHHHHHHCCCCCEECCHHHHHHEEECCCHHHHHCCCHHHHHHHHHHHHHH
DLGECFHETPLNDTDELLLLVVKNAKRTFGLIIKDIIGQREIVLKTLGGFFSESQIAFSG
HHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEC
ATILGDGRVVLILNLETF
CEEEECCEEEEEEEECCC
>Mature Secondary Structure 
TTNMLDLFIEEASEHLQALNDNLLQLEKDPTNGQLVSEIFRSAHTFKGMSATMGFQQVA
CCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHH
DLTHAMENVLDEVRNNRLAVTEHLVDIIFTCTSHLETMVSDIQHGGQGAADISKTVADLE
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ALLHPEQETDLAVEKTYRIQIQIEEAAILKAVRAVMCLERLAEMGIISETTPDREAIELE
HHHCCCCCCCCEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHH
EFEQSFEVVLESAQTKEEIEAVVLDISEIEKVTVTEEVEEVQVIEPIKKAAKQTTKRLEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KTIRVQLEKIEKLMNVFEESVIERARIDEIAEKTNNKELMEHLGRFSSISKEIQNGLLNM
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHCE
RMVPVDSVFNRFPKMVRTLAKELGKKIDLVIEGADTEVDKIVIDEIGDPLVHLIRNSVDH
EECCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHC
GAETVEVRRKNGKNETATINLKAFHSGNNVVIEIADDGAGINKRKVLEKAIAKNVVTRAE
CHHHHHHHHCCCCCCEEEEEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
STKMTDAEIFDLLFDSGFSTADQVSDLSGRGVGLDVVRNTILKIGGKISVESSENAGSTF
CCCCCHHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEE
RIEIPLTLSIIQSMLVATSERRYAVPLANVAEAITINPADIQHVHGKDLINYRETIIEVL
EEEECHHHHHHHHHHHHCCCCCEECCHHHHHHEEECCCHHHHHCCCHHHHHHHHHHHHHH
DLGECFHETPLNDTDELLLLVVKNAKRTFGLIIKDIIGQREIVLKTLGGFFSESQIAFSG
HHHHHHHCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEC
ATILGDGRVVLILNLETF
CEEEECCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]