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The map label for this gene is gufA [H]

Identifier: 226223043

GI number: 226223043

Start: 443326

End: 444135

Strand: Direct

Name: gufA [H]

Synonym: Lm4b_00437

Alternate gene names: 226223043

Gene position: 443326-444135 (Clockwise)

Preceding gene: 226223042

Following gene: 226223044

Centisome position: 15.22

GC content: 42.35

Gene sequence:

>810_bases
TTGTTAAATTACTTATCGTCACTAAATCCGGTACTGTTAGCACTTCTTGCCGGTATTTTTACATGGGCTTGTACCGCAGC
AGGAGCTTCACTCGTATTTTTCTTTAAAAATCTAAATAAAAAATGGGGCAATGTTATGCTAGGATTTGCTGCAGGCGTTA
TGCTCGCAGCAAGCTTCTGGTCGCTTCTTGCCCCTGCAATCGAAATGAGTAAAGATTTAGGGAAGTTTTCCTTCGTACCA
GCTCTAGTTGGCTTTTTGCTTGGGGGAATATTTTTACGTGTTATTGACCGTATTATTCCACATTTACATTTCGGGTTTCC
AGAGCAAGCGAAGGAAGGACCAAAAACTTCTCTTCGAAAAAGTATCTTACTGGTTCTTTCCATTACTATTCATAATATTC
CAGAAGGGGCAGCTGTTGGGGTAGCTTTCGGAGCAGTTATAACTGGAGACACGGAGACGCTTATTACTGCAATAGTTTTG
GCGCTTGGTATTGGTATTCAAAACTTTCCAGAGGGAGCGGCAGTATCCATTCCTTTGCGCGGAGAAGGGCTCTCGAGAGG
GAAAAGTTTCTGGTATGGCCAACTTTCAGCGGTAGTTGAACCAATTTTCGCTGTAATTGGTGCTGTATTGGTTGTTTTTG
TTACACCTATTTTGCCGTTTGCGCTGGCCTTTGCAGCAGGTGCAATGATTTTTGTTATTGTAGAGGAATTAATTCCTGAA
TCTCAAGTAGAAGGTTCGACCGATTTAGCAACTGCTGCAACGATGGCGGGATTTGCAGTAATGATGGTTTTAGATGTTGC
GTTAGGATAA

Upstream 100 bases:

>100_bases
GGGCTGTGAAAACAGGCGTAAATAAGACTCGTGCATTTGCTCAAGGCTTTAAACAAGGCTGGTCTGGTAAATAAAAGCAT
AGGAAAAGGGAGAGCATGAA

Downstream 100 bases:

>100_bases
AATAATAAACTGGACAAAAAACGACATTTAATATTTGCGGAATGCGTTTTTTTACGGTAAAATTAATAGTGAAATACTTC
ACAATATGTTAGTTTTCAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNVMLGFAAGVMLAASFWSLLAPAIEMSKDLGKFSFVP
ALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRKSILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVL
ALGIGIQNFPEGAAVSIPLRGEGLSRGKSFWYGQLSAVVEPIFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
SQVEGSTDLATAATMAGFAVMMVLDVALG

Sequences:

>Translated_269_residues
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNVMLGFAAGVMLAASFWSLLAPAIEMSKDLGKFSFVP
ALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRKSILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVL
ALGIGIQNFPEGAAVSIPLRGEGLSRGKSFWYGQLSAVVEPIFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
SQVEGSTDLATAATMAGFAVMMVLDVALG
>Mature_269_residues
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNVMLGFAAGVMLAASFWSLLAPAIEMSKDLGKFSFVP
ALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRKSILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVL
ALGIGIQNFPEGAAVSIPLRGEGLSRGKSFWYGQLSAVVEPIFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
SQVEGSTDLATAATMAGFAVMMVLDVALG

Specific function: Mediates Zinc Uptake. May Also Transport Other Divalent Cations Such As Copper And Cadmium Ions. [C]

COG id: COG0428

COG function: function code P; Predicted divalent heavy-metal cations transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI229577418, Length=334, Percent_Identity=45.8083832335329, Blast_Score=246, Evalue=1e-65,
Organism=Homo sapiens, GI229577422, Length=341, Percent_Identity=44.8680351906158, Blast_Score=244, Evalue=8e-65,
Organism=Escherichia coli, GI1789419, Length=262, Percent_Identity=29.0076335877863, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17507805, Length=322, Percent_Identity=39.4409937888199, Blast_Score=190, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24652846, Length=161, Percent_Identity=52.1739130434783, Blast_Score=174, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003689 [H]

Pfam domain/function: PF02535 Zip [H]

EC number: NA

Molecular weight: Translated: 28224; Mature: 28224

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNVMLGFAAGVMLAASFW
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLAPAIEMSKDLGKFSFVPALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
SILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVLALGIGIQNFPEGAAVSIPLR
HHHHHHHHHHHCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GEGLSRGKSFWYGQLSAVVEPIFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SQVEGSTDLATAATMAGFAVMMVLDVALG
HHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLNYLSSLNPVLLALLAGIFTWACTAAGASLVFFFKNLNKKWGNVMLGFAAGVMLAASFW
CCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLLAPAIEMSKDLGKFSFVPALVGFLLGGIFLRVIDRIIPHLHFGFPEQAKEGPKTSLRK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHHHH
SILLVLSITIHNIPEGAAVGVAFGAVITGDTETLITAIVLALGIGIQNFPEGAAVSIPLR
HHHHHHHHHHHCCCCCHHHHHHHHHHEECCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEC
GEGLSRGKSFWYGQLSAVVEPIFAVIGAVLVVFVTPILPFALAFAAGAMIFVIVEELIPE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
SQVEGSTDLATAATMAGFAVMMVLDVALG
HHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7934835 [H]