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The map label for this gene is inlF

Identifier: 226223039

GI number: 226223039

Start: 436571

End: 439042

Strand: Direct

Name: inlF

Synonym: Lm4b_00433

Alternate gene names: 226223039

Gene position: 436571-439042 (Clockwise)

Preceding gene: 226223038

Following gene: 226223042

Centisome position: 14.99

GC content: 35.6

Gene sequence:

>2472_bases
ATGAAAGCGAAAAATAATTTTTTTAAACAATTAATTTCCATAATGACTGTCTTGAGCCTTTTGTTCATGGTATTAGGTAT
TCAGGGTAATAATGAGGTTAAAGCAGCAACTTTAGCCACGCTACCAGCCCCGATTAATCAAATTTTCCCAGATGCAGATT
TAGCAGAAGGAATACGAGCAGTGCTTCAAAAAGCAAGTGTCACAGATGTAGTGACACAAGAAGAATTAGAAAGCATTACG
AAATTAGTAGTAGCCGGGGAAAAAGTAGCCTCCATTCAAGGGATCGAGTATTTAACTAATTTGGAGTACTTAAACCTTAA
TGGAAACCAAATTACTGATATTAGCCCATTAAGTAATTTAGTTAAATTAACGAATCTGTATATTGGAACTAATAAAATCA
CTGATATTAGTGCCTTGCAAAACTTAACTAATTTAAGGGAGCTATATCTTAATGAAGATAATATTAGCGATATTAGTCCA
TTAGCAAATTTAACTAAAATGTATTCTTTGAATTTGGGGGCTAATCATAACCTCAGTGATTTAAGTCCGTTAAGCAATAT
GACAGGTTTGAATTATTTGACAGTCACGGAGTCTAAAGTAAAAGATGTGACACCAATAGCCAATTTAACCGACTTATATA
GTTTAAGTTTGAATTATAATCAAATTGAAGATATAAGTCCGCTAGCTAGTTTGACAAGTTTACATTATTTTACAGCATAT
GTGAATCAAATTACTGATATTACTCCTGTAGCTAATATGACAAGGCTAAATTCTTTAAAGATAGGAAATAATAAAATTAC
TGATTTAAGCCCATTAGCTAATCTATCACAATTAACTTGGCTAGAAATCGGTACCAATCAAATTAGCGATATTAATGCGG
TTAAAGATTTAACTAAATTAAAAATGTTGAATGTTGGTAGTAACCAAATTAGTGATATATCTGTTCTAAATAATCTTTCC
CAATTGAATTCTTTATTCTTGAATAATAATCAACTTGGGAATGAAGATATGGAAGTGATTGGTGGATTAACTAATTTAAC
TACTTTATTTTTATCGCAAAATCATATTACAGACATAAGACCATTAGCAAGTTTAAGTAAAATGGATTCCGCTGACTTTG
CAAATCAGGTGATAAAAAAACCAGCACGTAATTTTTCGAAGACACTATCTGTTCCGAATAATATAACTAGCATAGATGGA
ACACTAGTTACTCCTAAGACAATTAGCAATAATGGAACCTACGACGCGCCAAACGTGAATTGGTCTTCGCCGAGCTATCT
TCCAGAAGTAAGATATACATTCAAGCAAGATGTGGTGGTGGGATCAACCACAAGTAGTTATACTGGTATCATAATTCAAC
CGCTAAATGAGCCAGTAGACTACAATGTCACATTTAATATAGACGGCAATACAAGCGAAGTAAAAACTGTAACAGAAGAA
GATCTAATTCCAGAACCTGCGAACCCGACCAAACAAGGTTATACATTTGATGGTTGGTACGACGCCGAAACAGGTGGAAC
AAAATGGGACTTTACAACTGGGCAAATGCCTGCAAATGATCTCATGCTATATGCCCATTTTTCCGTAAATAGTTATCAAG
TGAATTTTGATATAGATGGCGCAGTAATGAATGAAGCGGTAGTATACGATACTTTGCTCAATGAACCGACCGCTCCAACC
AAACAAGGTTATACATTCGATGGTTGGTATGACGCAGAAACAGGCGGTAATAAGTGGGATTTCAAAACGATGAAAATGCC
CGCAAATGATGTTACTTTATATGCACATTTTACTGTCAGCAGTTACCAAGTGAATTTTGATATAGATGGTGCGGTAACGA
ATGAAGCAATAGTATACGATACCTTACTCAATGAACCGGCGACTCCAACTAAACAAGGTTATACATTTGATGGCTGGTAT
GACGCAGAAACAGGCGGTAATAAGTGGGATTTCAAAACGATGAAAATGCCCGCAAATGATGTCACTTTATATGCGCATTT
TACCATCAACAACTATCAAGCTAATTTTGATATAGATGGTTCGGTAACGAATGAAACGATAACATATGATACCTTACTTA
ATGAACCGACTGCTCCAACCAAACAAGGTTTCCTTTTCGATGGGTGGTATGACGCAGAAGTAGGCGGAACAAAATGGGAT
TTTAACACGATGAAAATGCCTGCGAACGATATTAATTTGTACGCACATTTCAGTAAAGAAACGCCACTTATTCCTAGCCC
ATCTGACGAATCAGACTCGAAACCTACCAATGGATCAATCACTATAAATGAACCGAGTGCAACTAGTATGCCAGCCCAAA
ATAATAACATCACAGTAACAGCAGGGGAAAATACTCCAGAACTAACAACAGCTAAACTTCCGAAAACTGGAGATAATAAC
CCGTGGCAAACACTATTCGCCGGGATATTACTTTCATCATCCGCGTTTTATATTTGGAGAAAAAAAGCATAA

Upstream 100 bases:

>100_bases
TTTGCATATTAAAATTAGACAACTACTTCAAAATACGGTGTTACAATCAATAAGCCATAATAATGATTGTAAGTAAGCTT
AGTTGAAGGAAGGTACTAAA

Downstream 100 bases:

>100_bases
TTAAAAAACCCAGTATTTCCTAAAATGGAGATTACTGGGTTTTTGGTTTAATCAAGAATCTCAATATAGCCTTCTGTCCC
ATTGATGCGAATTTGCTGGC

Product: internalin, peptidoglycan bound protein (LPXTG motif)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 823; Mature: 823

Protein sequence:

>823_residues
MKAKNNFFKQLISIMTVLSLLFMVLGIQGNNEVKAATLATLPAPINQIFPDADLAEGIRAVLQKASVTDVVTQEELESIT
KLVVAGEKVASIQGIEYLTNLEYLNLNGNQITDISPLSNLVKLTNLYIGTNKITDISALQNLTNLRELYLNEDNISDISP
LANLTKMYSLNLGANHNLSDLSPLSNMTGLNYLTVTESKVKDVTPIANLTDLYSLSLNYNQIEDISPLASLTSLHYFTAY
VNQITDITPVANMTRLNSLKIGNNKITDLSPLANLSQLTWLEIGTNQISDINAVKDLTKLKMLNVGSNQISDISVLNNLS
QLNSLFLNNNQLGNEDMEVIGGLTNLTTLFLSQNHITDIRPLASLSKMDSADFANQVIKKPARNFSKTLSVPNNITSIDG
TLVTPKTISNNGTYDAPNVNWSSPSYLPEVRYTFKQDVVVGSTTSSYTGIIIQPLNEPVDYNVTFNIDGNTSEVKTVTEE
DLIPEPANPTKQGYTFDGWYDAETGGTKWDFTTGQMPANDLMLYAHFSVNSYQVNFDIDGAVMNEAVVYDTLLNEPTAPT
KQGYTFDGWYDAETGGNKWDFKTMKMPANDVTLYAHFTVSSYQVNFDIDGAVTNEAIVYDTLLNEPATPTKQGYTFDGWY
DAETGGNKWDFKTMKMPANDVTLYAHFTINNYQANFDIDGSVTNETITYDTLLNEPTAPTKQGFLFDGWYDAEVGGTKWD
FNTMKMPANDINLYAHFSKETPLIPSPSDESDSKPTNGSITINEPSATSMPAQNNNITVTAGENTPELTTAKLPKTGDNN
PWQTLFAGILLSSSAFYIWRKKA

Sequences:

>Translated_823_residues
MKAKNNFFKQLISIMTVLSLLFMVLGIQGNNEVKAATLATLPAPINQIFPDADLAEGIRAVLQKASVTDVVTQEELESIT
KLVVAGEKVASIQGIEYLTNLEYLNLNGNQITDISPLSNLVKLTNLYIGTNKITDISALQNLTNLRELYLNEDNISDISP
LANLTKMYSLNLGANHNLSDLSPLSNMTGLNYLTVTESKVKDVTPIANLTDLYSLSLNYNQIEDISPLASLTSLHYFTAY
VNQITDITPVANMTRLNSLKIGNNKITDLSPLANLSQLTWLEIGTNQISDINAVKDLTKLKMLNVGSNQISDISVLNNLS
QLNSLFLNNNQLGNEDMEVIGGLTNLTTLFLSQNHITDIRPLASLSKMDSADFANQVIKKPARNFSKTLSVPNNITSIDG
TLVTPKTISNNGTYDAPNVNWSSPSYLPEVRYTFKQDVVVGSTTSSYTGIIIQPLNEPVDYNVTFNIDGNTSEVKTVTEE
DLIPEPANPTKQGYTFDGWYDAETGGTKWDFTTGQMPANDLMLYAHFSVNSYQVNFDIDGAVMNEAVVYDTLLNEPTAPT
KQGYTFDGWYDAETGGNKWDFKTMKMPANDVTLYAHFTVSSYQVNFDIDGAVTNEAIVYDTLLNEPATPTKQGYTFDGWY
DAETGGNKWDFKTMKMPANDVTLYAHFTINNYQANFDIDGSVTNETITYDTLLNEPTAPTKQGFLFDGWYDAEVGGTKWD
FNTMKMPANDINLYAHFSKETPLIPSPSDESDSKPTNGSITINEPSATSMPAQNNNITVTAGENTPELTTAKLPKTGDNN
PWQTLFAGILLSSSAFYIWRKKA
>Mature_823_residues
MKAKNNFFKQLISIMTVLSLLFMVLGIQGNNEVKAATLATLPAPINQIFPDADLAEGIRAVLQKASVTDVVTQEELESIT
KLVVAGEKVASIQGIEYLTNLEYLNLNGNQITDISPLSNLVKLTNLYIGTNKITDISALQNLTNLRELYLNEDNISDISP
LANLTKMYSLNLGANHNLSDLSPLSNMTGLNYLTVTESKVKDVTPIANLTDLYSLSLNYNQIEDISPLASLTSLHYFTAY
VNQITDITPVANMTRLNSLKIGNNKITDLSPLANLSQLTWLEIGTNQISDINAVKDLTKLKMLNVGSNQISDISVLNNLS
QLNSLFLNNNQLGNEDMEVIGGLTNLTTLFLSQNHITDIRPLASLSKMDSADFANQVIKKPARNFSKTLSVPNNITSIDG
TLVTPKTISNNGTYDAPNVNWSSPSYLPEVRYTFKQDVVVGSTTSSYTGIIIQPLNEPVDYNVTFNIDGNTSEVKTVTEE
DLIPEPANPTKQGYTFDGWYDAETGGTKWDFTTGQMPANDLMLYAHFSVNSYQVNFDIDGAVMNEAVVYDTLLNEPTAPT
KQGYTFDGWYDAETGGNKWDFKTMKMPANDVTLYAHFTVSSYQVNFDIDGAVTNEAIVYDTLLNEPATPTKQGYTFDGWY
DAETGGNKWDFKTMKMPANDVTLYAHFTINNYQANFDIDGSVTNETITYDTLLNEPTAPTKQGFLFDGWYDAEVGGTKWD
FNTMKMPANDINLYAHFSKETPLIPSPSDESDSKPTNGSITINEPSATSMPAQNNNITVTAGENTPELTTAKLPKTGDNN
PWQTLFAGILLSSSAFYIWRKKA

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=254, Percent_Identity=29.9212598425197, Blast_Score=95, Evalue=3e-19,
Organism=Homo sapiens, GI42544233, Length=284, Percent_Identity=27.112676056338, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI42544231, Length=284, Percent_Identity=27.112676056338, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI288541295, Length=289, Percent_Identity=26.9896193771626, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI288541297, Length=289, Percent_Identity=26.9896193771626, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI21389483, Length=221, Percent_Identity=28.9592760180996, Blast_Score=69, Evalue=3e-11,
Organism=Homo sapiens, GI55743114, Length=171, Percent_Identity=30.4093567251462, Blast_Score=69, Evalue=3e-11,
Organism=Homo sapiens, GI157694513, Length=338, Percent_Identity=24.8520710059172, Blast_Score=68, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17554124, Length=217, Percent_Identity=30.8755760368664, Blast_Score=89, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536161, Length=256, Percent_Identity=27.734375, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17531555, Length=185, Percent_Identity=31.8918918918919, Blast_Score=82, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI71984630, Length=353, Percent_Identity=24.6458923512748, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17508137, Length=321, Percent_Identity=26.4797507788162, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21358617, Length=212, Percent_Identity=28.3018867924528, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17136436, Length=325, Percent_Identity=27.6923076923077, Blast_Score=71, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17136634, Length=286, Percent_Identity=29.7202797202797, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 90697; Mature: 90697

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKNNFFKQLISIMTVLSLLFMVLGIQGNNEVKAATLATLPAPINQIFPDADLAEGIRA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHCCCCHHHHHHHH
VLQKASVTDVVTQEELESITKLVVAGEKVASIQGIEYLTNLEYLNLNGNQITDISPLSNL
HHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHCCCEEEECCCCEEECCHHHHHH
VKLTNLYIGTNKITDISALQNLTNLRELYLNEDNISDISPLANLTKMYSLNLGANHNLSD
HHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCCCC
LSPLSNMTGLNYLTVTESKVKDVTPIANLTDLYSLSLNYNQIEDISPLASLTSLHYFTAY
CCHHHHCCCCEEEEEECHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
VNQITDITPVANMTRLNSLKIGNNKITDLSPLANLSQLTWLEIGTNQISDINAVKDLTKL
HHHHCCCCCCCCHHHCCEEEECCCCCCCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHH
KMLNVGSNQISDISVLNNLSQLNSLFLNNNQLGNEDMEVIGGLTNLTTLFLSQNHITDIR
EEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHCCHHHHEEEEECCCCCCCHH
PLASLSKMDSADFANQVIKKPARNFSKTLSVPNNITSIDGTLVTPKTISNNGTYDAPNVN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEECCEEECCCCCCCCCCCC
WSSPSYLPEVRYTFKQDVVVGSTTSSYTGIIIQPLNEPVDYNVTFNIDGNTSEVKTVTEE
CCCCCCCCHHHHEEECCEEEECCCCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEEHHH
DLIPEPANPTKQGYTFDGWYDAETGGTKWDFTTGQMPANDLMLYAHFSVNSYQVNFDIDG
CCCCCCCCCCCCCCEECCEEECCCCCCEEEEECCCCCCCCEEEEEEEECCEEEEEEEECC
AVMNEAVVYDTLLNEPTAPTKQGYTFDGWYDAETGGNKWDFKTMKMPANDVTLYAHFTVS
HHHCCHHHHHHHHCCCCCCCCCCCEECCEEECCCCCCCCCEEEEECCCCCEEEEEEEEEE
SYQVNFDIDGAVTNEAIVYDTLLNEPATPTKQGYTFDGWYDAETGGNKWDFKTMKMPAND
EEEEEEEECCCCCCCEEEEEHHHCCCCCCCCCCCEECCEEECCCCCCCCCEEEEECCCCC
VTLYAHFTINNYQANFDIDGSVTNETITYDTLLNEPTAPTKQGFLFDGWYDAEVGGTKWD
EEEEEEEEEECEEEEEEECCCCCCCEEEEHHHCCCCCCCCCCCEEECCEEECCCCCCEEC
FNTMKMPANDINLYAHFSKETPLIPSPSDESDSKPTNGSITINEPSATSMPAQNNNITVT
CCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEE
AGENTPELTTAKLPKTGDNNPWQTLFAGILLSSSAFYIWRKKA
ECCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure
MKAKNNFFKQLISIMTVLSLLFMVLGIQGNNEVKAATLATLPAPINQIFPDADLAEGIRA
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHCCCCHHHHHHHH
VLQKASVTDVVTQEELESITKLVVAGEKVASIQGIEYLTNLEYLNLNGNQITDISPLSNL
HHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHCCHHHHCCCEEEECCCCEEECCHHHHHH
VKLTNLYIGTNKITDISALQNLTNLRELYLNEDNISDISPLANLTKMYSLNLGANHNLSD
HHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHEEEECCCCCCCCC
LSPLSNMTGLNYLTVTESKVKDVTPIANLTDLYSLSLNYNQIEDISPLASLTSLHYFTAY
CCHHHHCCCCEEEEEECHHHCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHH
VNQITDITPVANMTRLNSLKIGNNKITDLSPLANLSQLTWLEIGTNQISDINAVKDLTKL
HHHHCCCCCCCCHHHCCEEEECCCCCCCCHHHCCCCCEEEEEECCCCCCHHHHHHHHHHH
KMLNVGSNQISDISVLNNLSQLNSLFLNNNQLGNEDMEVIGGLTNLTTLFLSQNHITDIR
EEEECCCCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHCCHHHHEEEEECCCCCCCHH
PLASLSKMDSADFANQVIKKPARNFSKTLSVPNNITSIDGTLVTPKTISNNGTYDAPNVN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCEEECCEEECCCCCCCCCCCC
WSSPSYLPEVRYTFKQDVVVGSTTSSYTGIIIQPLNEPVDYNVTFNIDGNTSEVKTVTEE
CCCCCCCCHHHHEEECCEEEECCCCCCCEEEEEECCCCCCEEEEEEECCCCCCEEEEHHH
DLIPEPANPTKQGYTFDGWYDAETGGTKWDFTTGQMPANDLMLYAHFSVNSYQVNFDIDG
CCCCCCCCCCCCCCEECCEEECCCCCCEEEEECCCCCCCCEEEEEEEECCEEEEEEEECC
AVMNEAVVYDTLLNEPTAPTKQGYTFDGWYDAETGGNKWDFKTMKMPANDVTLYAHFTVS
HHHCCHHHHHHHHCCCCCCCCCCCEECCEEECCCCCCCCCEEEEECCCCCEEEEEEEEEE
SYQVNFDIDGAVTNEAIVYDTLLNEPATPTKQGYTFDGWYDAETGGNKWDFKTMKMPAND
EEEEEEEECCCCCCCEEEEEHHHCCCCCCCCCCCEECCEEECCCCCCCCCEEEEECCCCC
VTLYAHFTINNYQANFDIDGSVTNETITYDTLLNEPTAPTKQGFLFDGWYDAEVGGTKWD
EEEEEEEEEECEEEEEEECCCCCCCEEEEHHHCCCCCCCCCCCEEECCEEECCCCCCEEC
FNTMKMPANDINLYAHFSKETPLIPSPSDESDSKPTNGSITINEPSATSMPAQNNNITVT
CCEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCEEEE
AGENTPELTTAKLPKTGDNNPWQTLFAGILLSSSAFYIWRKKA
ECCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]