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The map label for this gene is essB [H]

Identifier: 226222705

GI number: 226222705

Start: 71114

End: 72310

Strand: Direct

Name: essB [H]

Synonym: Lm4b_00069

Alternate gene names: 226222705

Gene position: 71114-72310 (Clockwise)

Preceding gene: 226222704

Following gene: 226222706

Centisome position: 2.44

GC content: 35.59

Gene sequence:

>1197_bases
ATGAATAAGACAATTGAAATGGACGGAACAACTTACGATTTTACTTATGAGGATCTAGTTTGGAGCATTACGTTTCCAAA
ATCAAAAACACGCGCTAAAGAACTCGCACAACTAGAACTATTAGAAAAACCTGCGACACATTTTACTCCTGCAAAAATCT
CAAGTGATAGCGATTCGTATACAATTTCTTATGAGATTGCGAAACGTACTTATGGATTTGAACAAGTTCGAAAAATGGGA
CGTGAAGATAAACTGCGCGCACTGCGGAATATTGCGGATTTAGGCGAATTGTTAAACACGCGCTATACATTCTTTTTACA
CCCGGATAATCTGATTTTCGATATTAACTTAGTGCCAAGTATTGTTCATCGGGGCATTAAAAATATATTACCGCCTTATG
AACTAACAGAAGAAACTTTTTTCAAACAATATCAATGTTTCGTTATTGCGATGTTTTCTAAGAAATTCTCTTTTGAAAAC
TTGTACAATGGCTCGCTATCAGGGGCTAGAGGAACGCAATTTGAGAAGAGTATATTAGATGCAAAAACGGTGCAAGATAT
TGCTACTATTTTAGAAGAAGCATACGTGAAAGAACATGCGGCGGTTCAAAAAAATATGGCAAGCGTACCGAAGAAAAAAT
ACAGTACTTTCCGTGGGTTGGCGGTTGGTTTCATTATCGTCGCTATTTTACTTGCAATTCCAGTAAGTTATTTTGCCTTC
GTTAAAGTCCCTCTGCAAAATGACTTACTAACGGCAAACGAGAATTTCCTGAAAACAGATTACGATAAAGTGATTACAGG
TCTAGAAAATGTGGATCCAGAAAAAATGCCGCAGTCTGTCCAATATGAATTAGCTTATTCCTATGTTAAAGGCGAAAAAA
TGAGCGATAAAAAGAAAGAAAACATTATGAATACAATCAGCTTAAAATCTGACGCCAAAAACTTACTTTACTGGATTTAC
AATGGTCGCGGAGAATTTAGTAAATCACTTGATATTGCCAAACTTTTAGACGACCCAACGCTTGCGATGTACAGTTTAAC
AAAACAAATTGAACAGGTACAAAGTGATACAACATTAAGCGGCGATGAAAAAGTGGAAAAACTAAAAACTTTGGAAGAAA
GCTTGAAAGAATACGATGAAAAAGTAAATGAATCAACTACAACTGAAGATGAAACAACAAATACAGAAGCAAAATAA

Upstream 100 bases:

>100_bases
TAAAGCGATATTACTAAGCGATGATGACAAATTGACTAATTTTCAAATTGCGGACGGAGACATCTTAGAAATTTTATAGA
AAAAAAGGAGAATAAAAACG

Downstream 100 bases:

>100_bases
GGGAGAATGGACCATGAATAGAGAGGCTTTATTAATTGTTAGTAACGGGCAGCAATGTCATAAAAACCACTTGTCTCCTG
AAAAAGTCGTGACAATTGGG

Product: YukC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNKTIEMDGTTYDFTYEDLVWSITFPKSKTRAKELAQLELLEKPATHFTPAKISSDSDSYTISYEIAKRTYGFEQVRKMG
REDKLRALRNIADLGELLNTRYTFFLHPDNLIFDINLVPSIVHRGIKNILPPYELTEETFFKQYQCFVIAMFSKKFSFEN
LYNGSLSGARGTQFEKSILDAKTVQDIATILEEAYVKEHAAVQKNMASVPKKKYSTFRGLAVGFIIVAILLAIPVSYFAF
VKVPLQNDLLTANENFLKTDYDKVITGLENVDPEKMPQSVQYELAYSYVKGEKMSDKKKENIMNTISLKSDAKNLLYWIY
NGRGEFSKSLDIAKLLDDPTLAMYSLTKQIEQVQSDTTLSGDEKVEKLKTLEESLKEYDEKVNESTTTEDETTNTEAK

Sequences:

>Translated_398_residues
MNKTIEMDGTTYDFTYEDLVWSITFPKSKTRAKELAQLELLEKPATHFTPAKISSDSDSYTISYEIAKRTYGFEQVRKMG
REDKLRALRNIADLGELLNTRYTFFLHPDNLIFDINLVPSIVHRGIKNILPPYELTEETFFKQYQCFVIAMFSKKFSFEN
LYNGSLSGARGTQFEKSILDAKTVQDIATILEEAYVKEHAAVQKNMASVPKKKYSTFRGLAVGFIIVAILLAIPVSYFAF
VKVPLQNDLLTANENFLKTDYDKVITGLENVDPEKMPQSVQYELAYSYVKGEKMSDKKKENIMNTISLKSDAKNLLYWIY
NGRGEFSKSLDIAKLLDDPTLAMYSLTKQIEQVQSDTTLSGDEKVEKLKTLEESLKEYDEKVNESTTTEDETTNTEAK
>Mature_398_residues
MNKTIEMDGTTYDFTYEDLVWSITFPKSKTRAKELAQLELLEKPATHFTPAKISSDSDSYTISYEIAKRTYGFEQVRKMG
REDKLRALRNIADLGELLNTRYTFFLHPDNLIFDINLVPSIVHRGIKNILPPYELTEETFFKQYQCFVIAMFSKKFSFEN
LYNGSLSGARGTQFEKSILDAKTVQDIATILEEAYVKEHAAVQKNMASVPKKKYSTFRGLAVGFIIVAILLAIPVSYFAF
VKVPLQNDLLTANENFLKTDYDKVITGLENVDPEKMPQSVQYELAYSYVKGEKMSDKKKENIMNTISLKSDAKNLLYWIY
NGRGEFSKSLDIAKLLDDPTLAMYSLTKQIEQVQSDTTLSGDEKVEKLKTLEESLKEYDEKVNESTTTEDETTNTEAK

Specific function: Required for secretion of esxA and esxB [H]

COG id: COG4499

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the essB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018778 [H]

Pfam domain/function: PF10140 essB [H]

EC number: NA

Molecular weight: Translated: 45497; Mature: 45497

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTIEMDGTTYDFTYEDLVWSITFPKSKTRAKELAQLELLEKPATHFTPAKISSDSDSY
CCCEEECCCCEEEEEHHHEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
TISYEIAKRTYGFEQVRKMGREDKLRALRNIADLGELLNTRYTFFLHPDNLIFDINLVPS
EEEEEHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECHHHH
IVHRGIKNILPPYELTEETFFKQYQCFVIAMFSKKFSFENLYNGSLSGARGTQFEKSILD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHH
AKTVQDIATILEEAYVKEHAAVQKNMASVPKKKYSTFRGLAVGFIIVAILLAIPVSYFAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVPLQNDLLTANENFLKTDYDKVITGLENVDPEKMPQSVQYELAYSYVKGEKMSDKKKE
EECCCCCCCCCCCCCHHHCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCCCHHHHH
NIMNTISLKSDAKNLLYWIYNGRGEFSKSLDIAKLLDDPTLAMYSLTKQIEQVQSDTTLS
HHHHHHHHHCCCCCEEEEEECCCCCCHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GDEKVEKLKTLEESLKEYDEKVNESTTTEDETTNTEAK
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKTIEMDGTTYDFTYEDLVWSITFPKSKTRAKELAQLELLEKPATHFTPAKISSDSDSY
CCCEEECCCCEEEEEHHHEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
TISYEIAKRTYGFEQVRKMGREDKLRALRNIADLGELLNTRYTFFLHPDNLIFDINLVPS
EEEEEHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECHHHH
IVHRGIKNILPPYELTEETFFKQYQCFVIAMFSKKFSFENLYNGSLSGARGTQFEKSILD
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHH
AKTVQDIATILEEAYVKEHAAVQKNMASVPKKKYSTFRGLAVGFIIVAILLAIPVSYFAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VKVPLQNDLLTANENFLKTDYDKVITGLENVDPEKMPQSVQYELAYSYVKGEKMSDKKKE
EECCCCCCCCCCCCCHHHCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHCCCCCCHHHHH
NIMNTISLKSDAKNLLYWIYNGRGEFSKSLDIAKLLDDPTLAMYSLTKQIEQVQSDTTLS
HHHHHHHHHCCCCCEEEEEECCCCCCHHCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GDEKVEKLKTLEESLKEYDEKVNESTTTEDETTNTEAK
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA