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The map label for this gene is agrA [H]

Identifier: 226222696

GI number: 226222696

Start: 60123

End: 60851

Strand: Direct

Name: agrA [H]

Synonym: Lm4b_00060

Alternate gene names: 226222696

Gene position: 60123-60851 (Clockwise)

Preceding gene: 226222695

Following gene: 226222697

Centisome position: 2.06

GC content: 34.98

Gene sequence:

>729_bases
ATGCTACCGGTTTTTATTTGTGAAGATAACAGAATGCAGCGAGAAAGGTTAACGAAATATATTGAAGACTATATTATGGT
TGAACATTTTGATATGAAGTTAGAACTTTCAACAGGAGATCCGTTTGAGTTAGTATCACGAATGCCTACACATCAAGGTA
TGGGGCTTTATTTTTTAGATATTGATTTAGGGCAGCCGGACATGAATGGTTTTGAATTAGCTCAGGAAATTCGGAAGTTT
GATCCGCGTGGTTTCATTATTTTTATTACAACACATGCGGAGTTAAGTTATATGACTTTCACGTATAAGGTGGAAGCGCT
TGATTACATTATTAAAGACGATATTGATTTGCTGCATGACCGGGTACTTGCCTGTATGAAGCAAGCAGAAGAACGGATTT
CCAATGATCAAGATATGCAGAAGTATTTTACGTTTAAAGTGTCGGATAAGAAGATTATTCATGAACTTTTAGACGATATC
TTATTTTTTGAAACAGCCCCAACTATCCATAAAGTAATTTTACATGGCAAAAATCGCCAAGTGGAATTTTATGGTAAGTT
GAAGAATATCGAGAAAATGTTGGACGAATCATTTTATCGGTGCCACAGGTCGTATATTGTGAATAAGAAAAATATTCATG
AGCTGGATACGACAAAAGGTGTGGTGAAGATGTCTAACGGTGAAAATTGTTACGCATCATCGAAATTAATTAAAAGCTTG
AGTTTATAA

Upstream 100 bases:

>100_bases
AATTATGAAGAAATATTCGCACGTTGCCTTAGATACGAAAGTGACCGATAGAGAAGTTATTCAAGAATTAGAAATTATGT
AGAAGAATGGGGATGAATTT

Downstream 100 bases:

>100_bases
AAGTGGCCTTAAAGGTCGCTTTTTTTGTACGTGGCAAGTTTGGATTTGATGAAATGGGTAAATATAGGTAAAATAATAGT
GATGAATTGTTAGTTAAGTT

Product: response regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MLPVFICEDNRMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPTHQGMGLYFLDIDLGQPDMNGFELAQEIRKF
DPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDLLHDRVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDI
LFFETAPTIHKVILHGKNRQVEFYGKLKNIEKMLDESFYRCHRSYIVNKKNIHELDTTKGVVKMSNGENCYASSKLIKSL
SL

Sequences:

>Translated_242_residues
MLPVFICEDNRMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPTHQGMGLYFLDIDLGQPDMNGFELAQEIRKF
DPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDLLHDRVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDI
LFFETAPTIHKVILHGKNRQVEFYGKLKNIEKMLDESFYRCHRSYIVNKKNIHELDTTKGVVKMSNGENCYASSKLIKSL
SL
>Mature_242_residues
MLPVFICEDNRMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPTHQGMGLYFLDIDLGQPDMNGFELAQEIRKF
DPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDLLHDRVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDI
LFFETAPTIHKVILHGKNRQVEFYGKLKNIEKMLDESFYRCHRSYIVNKKNIHELDTTKGVVKMSNGENCYASSKLIKSL
SL

Specific function: Required for high-level post-exponential phase expression of a series of secreted proteins [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788724, Length=227, Percent_Identity=27.3127753303965, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28550; Mature: 28550

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPVFICEDNRMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPTHQGMGLYFLD
CCEEEEECCCCHHHHHHHHHHHHHHHEEEECEEEEECCCCHHHHHHCCCCCCCCEEEEEE
IDLGQPDMNGFELAQEIRKFDPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDLLHD
EECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEHHHHHHHHHHHHHHHHH
RVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDILFFETAPTIHKVILHGKNRQ
HHHHHHHHHHHHHCCCHHHHHHHEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE
VEFYGKLKNIEKMLDESFYRCHRSYIVNKKNIHELDTTKGVVKMSNGENCYASSKLIKSL
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEEEECCCCCCHHHHHHHHHH
SL
CC
>Mature Secondary Structure
MLPVFICEDNRMQRERLTKYIEDYIMVEHFDMKLELSTGDPFELVSRMPTHQGMGLYFLD
CCEEEEECCCCHHHHHHHHHHHHHHHEEEECEEEEECCCCHHHHHHCCCCCCCCEEEEEE
IDLGQPDMNGFELAQEIRKFDPRGFIIFITTHAELSYMTFTYKVEALDYIIKDDIDLLHD
EECCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEEEEHHHHHHHHHHHHHHHHH
RVLACMKQAEERISNDQDMQKYFTFKVSDKKIIHELLDDILFFETAPTIHKVILHGKNRQ
HHHHHHHHHHHHHCCCHHHHHHHEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCE
VEFYGKLKNIEKMLDESFYRCHRSYIVNKKNIHELDTTKGVVKMSNGENCYASSKLIKSL
EEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCEEEECCCCCCHHHHHHHHHH
SL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA