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The map label for this gene is adcB [H]

Identifier: 225861988

GI number: 225861988

Start: 2038318

End: 2039124

Strand: Reverse

Name: adcB [H]

Synonym: SPT_2183

Alternate gene names: 225861988

Gene position: 2039124-2038318 (Counterclockwise)

Preceding gene: 225861989

Following gene: 225861987

Centisome position: 96.54

GC content: 43.0

Gene sequence:

>807_bases
ATGCTTAGTTTATTATCTTACGACTTTATACAACGCGCCTTTTTGGCGGTTATTGCTATGAGTCTTTTCTCACCGGTATT
GGGAACCTTCCTCATCTTGCGTCGTCAGAGTTTGATGAGTGATACCCTTAGCCACGTCTCACTTTCAGGTGTAGCCTTTG
GTCTGGTTTTGGGGATTTCTCCAACTGTTTCTACTATTGCCATTGTCTTGATTGCGGCGGTCTTTCTGGAGTATCTCCGT
ACGGTTTACAAGAGCTTTATGGAAATCGGGACAGCTATCCTCATGTCAACAGGTCTGGCTGTTTCTCTGATTGTCATGAG
CAAGGGTAAAAGCTCGAGTTCAATGAGTTTGGACCAATATCTCTTTGGTTCGATCGTGACTATCAGTGAAGAACAGGTCA
TTTCCCTCTTTGTCATTGCGGCGGTTGTTTTGATTTTGACCTTTCTCTTTCTTCGTCCTATGTATATCTTAACTTTTGAC
GAAGATACGGCCTTTGTGGATGGCTTGCCAGTTCGTACCATGTCCATTCTTTTTAACATGGTGACAGGGGTGGCTATTGC
CCTTATGATTCCTGCAGCAGGAGCTCTTCTGGTATCGACCATTATGGTCTTGCCAGCTAGTATTGCCCTGCGTCTGGGGA
AAAACTTTAAATCGGTTATGCTGCTTGCCAGTGCGATTGGCTTTTTGGGAATGGTAGCAGGACTTTACATTTCCTACTAT
GCAGAAACACCTGCAAGTGCAAGTATTACCATTATTTTTGTAACTGTCTTTATACTAATCAGTTTAGTAAGACGTTTTAT
CAAATAG

Upstream 100 bases:

>100_bases
GAAGTTAAGGATTATGCGGATCGCAATATTCATCTAGTCCGTAACCAAGACTCGCCATGGCGTTGTTTCAATGTTCATGA
GAATGGCCAGGAGGTGGGCC

Downstream 100 bases:

>100_bases
GAGACGAACGTGAAAAAAATTAGCTTATTACTAGCCAGTCTATGTGCCTTGTTTTTAGTGGCTTGTTCCAATCAAAAACA
GGCAGATGGTAAACTCAATA

Product: ABC transporter membrane-spanning permease - Zinc

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLSHVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLR
TVYKSFMEIGTAILMSTGLAVSLIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKSVMLLASAIGFLGMVAGLYISYY
AETPASASITIIFVTVFILISLVRRFIK

Sequences:

>Translated_268_residues
MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLSHVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLR
TVYKSFMEIGTAILMSTGLAVSLIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKSVMLLASAIGFLGMVAGLYISYY
AETPASASITIIFVTVFILISLVRRFIK
>Mature_268_residues
MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLSHVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLR
TVYKSFMEIGTAILMSTGLAVSLIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKSVMLLASAIGFLGMVAGLYISYY
AETPASASITIIFVTVFILISLVRRFIK

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable). Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=253, Percent_Identity=30.4347826086957, Blast_Score=117, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 28890; Mature: 28890

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLSHVSLSGVAFGLVLGIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVSLIVMSKGKSSSSMSLDQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHH
LFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFDEDTAFVDGLPVRTMSILFNM
HHHHHHEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCHHHHHHHHHH
VTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKSVMLLASAIGFLGMVAGLYISYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AETPASASITIIFVTVFILISLVRRFIK
HCCCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLSHVSLSGVAFGLVLGIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVSLIVMSKGKSSSSMSLDQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHH
LFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFDEDTAFVDGLPVRTMSILFNM
HHHHHHEECHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHCCCCHHHHHHHHHH
VTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKSVMLLASAIGFLGMVAGLYISYY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
AETPASASITIIFVTVFILISLVRRFIK
HCCCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]