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The map label for this gene is oxaA1

Identifier: 225861860

GI number: 225861860

Start: 1898996

End: 1899769

Strand: Reverse

Name: oxaA1

Synonym: SPT_2036

Alternate gene names: 225861860

Gene position: 1899769-1898996 (Counterclockwise)

Preceding gene: 225861861

Following gene: 225861859

Centisome position: 89.94

GC content: 41.73

Gene sequence:

>774_bases
ATGACAGCCTGTGCGACTAATGGGGTAACTAGCGATATTACAGCCGAATCGGCTGATTTTTGGAGTAAATTGGTTTACTT
CTTTGCGGAAATCATTCGCTTTTTATCGTTTGATATTAGTATCGGAGTGGGGATTATTCTCTTTACGGTCTTGATTCGTA
CAGTCCTCTTGCCAGTCTTTCAGGTGCAAATGGTGGCTTCTAGGAAAATGCAGGAAGCTCAGCCACGCATTAAGGCGCTT
CGAGAACAATATCCAGGTCGAGATATGGAAAGCAGAACCAAACTAGAGCAGGAAATGCGTAAAGTATTTAAAGAAATGGG
TGTCAGACAGTCAGACTCTCTTTGGCCGATTTTGATTCAGATGCCGGTTATTTTGGCCTTGTTCCAAGCCCTATCAAGAG
TTGACTTTTTAAAGACAGGTCATTTCTTATGGATTAACCTTGGTAGTGTGGATACAACCCTTGTTCTTCCGATTTTAGCA
GCAGTATTCACCTTTTTAAGTACTTGGTTGTCCAACAAAGCTTTGTCTGAGCGAAATGGCGCTACGACTGCGATGATGTA
TGGGATTCCAGTCTTGATTTTTATCTTTGCAGTTTATGCGCCAGGTGGAGTCGCCCTATACTGGACAGTGTCTAATGCTT
ATCAAGTCTTGCAAACCTATTTCTTGAATAATCCATTCAAGATTATCGCAGAGCGCGAGGCCGTAGTACAGGCACAAAAA
GATTTGGAAAATAGAAAAAGAAAAGCCAAGAAAAAGGCTCAGAAAACGAAATAA

Upstream 100 bases:

>100_bases
CTACTCCATGTATTAAAATTATCAAAGATTTACCGGGAAGGAAATGGGAGTGAAAAAGAAACTAAAGTTGACTAGTTTGC
TAGGACTGTCTCTGTTAATC

Downstream 100 bases:

>100_bases
ATAAGGAGGAATCTGGTAATGGTAGTATTTACAGGTTCAACTGTTGAAGAAGCAATCCAGAAAGGATTGAAAGAATTAGA
TATTCCAAGAATGAAGGCTC

Product: membrane protein OxaA 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKAL
REQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFLWINLGSVDTTLVLPILA
AVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQK
DLENRKRKAKKKAQKTK

Sequences:

>Translated_257_residues
MTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKAL
REQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFLWINLGSVDTTLVLPILA
AVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQK
DLENRKRKAKKKAQKTK
>Mature_256_residues
TACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALR
EQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFLWINLGSVDTTLVLPILAA
VFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKD
LENRKRKAKKKAQKTK

Specific function: Required for the insertion of integral membrane proteins into the membrane. May also be involved in protein secretion processes

COG id: COG0706

COG function: function code U; Preprotein translocase subunit YidC

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the OXA1/oxaA family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1790140, Length=209, Percent_Identity=29.6650717703349, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OXAA1_STRR6 (Q8DN93)

Other databases:

- EMBL:   AE007317
- PIR:   B98103
- RefSeq:   NP_359444.1
- STRING:   Q8DN93
- EnsemblBacteria:   EBSTRT00000015620
- GeneID:   933908
- GenomeReviews:   AE007317_GR
- KEGG:   spr:spr1852
- eggNOG:   COG0706
- GeneTree:   EBGT00050000027293
- HOGENOM:   HBG560622
- OMA:   MKSAPER
- ProtClustDB:   CLSK803899
- BioCyc:   SPNE171101:SPR1852-MONOMER
- HAMAP:   MF_01811
- InterPro:   IPR001708
- InterPro:   IPR023060
- PANTHER:   PTHR12428
- PRINTS:   PR00701
- TIGRFAMs:   TIGR03592

Pfam domain/function: PF02096 60KD_IMP

EC number: NA

Molecular weight: Translated: 29176; Mature: 29045

Theoretical pI: Translated: 10.35; Mature: 10.35

Prosite motif: PS51257 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x166bc84c)-; HASH(0x183ad984)-; HASH(0x186d4ea8)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVQMVASRKMQEAQPRIKALREQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
MPVILALFQALSRVDFLKTGHFLWINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNG
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQK
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DLENRKRKAKKKAQKTK
HHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
TACATNGVTSDITAESADFWSKLVYFFAEIIRFLSFDISIGVGIILFTVLIRTVLLPVF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QVQMVASRKMQEAQPRIKALREQYPGRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
MPVILALFQALSRVDFLKTGHFLWINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNG
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
ATTAMMYGIPVLIFIFAVYAPGGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQK
CHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
DLENRKRKAKKKAQKTK
HHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11544234