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The map label for this gene is trkA

Identifier: 225858323

GI number: 225858323

Start: 490166

End: 491515

Strand: Reverse

Name: trkA

Synonym: SP70585_0543

Alternate gene names: 225858323

Gene position: 491515-490166 (Counterclockwise)

Preceding gene: 225858335

Following gene: 225858322

Centisome position: 22.5

GC content: 42.59

Gene sequence:

>1350_bases
ATGAAAATTATCCTTGTCGGAGGGGGAAAAGTTGGTTTTGCCCTCTGTCGCTCCTTGGTTGCAGAAAAGCATGATGTTTT
GCTGATTGAGCAAGACGAAGCTGTTCTCAATCATATTGTCAGTCGCTTTGATATCATTGGTATCCTTGGTAACGGGGCCG
ATTTTGCCATTCTTGAGCAAGCCAGCGTCCAAGATTGTGATATCTTTATCGCCCTGACTGAGCACGATGAAGTCAACATG
ATTGCAGCAGTTCTAGCCAAGAAAATGGGAGCTAAAGAAACTATCGTTCGGGTGCGGAACCCTGAATATTCTAACTCTTA
TTTCAAGGAAAAGAATATTCTCGGTTTTTCTCTTATCGTTAATCCTGAGCTCTTGGCTGCCCGCGCTATCGCGAATATCA
TTGACTTCCCCAACGCCCTGTCTGTCGAACGCTTTGCTGGTGGACGCGTTAGCCTCATGGAATTTGTCGTCAAGTCCACC
AGCGGTCTTTGCCAAATGCCCATTTCTGATTTTCGTAAAAAATTTGGTAATGTCATTGTCTGTGCGATAGAGAGGGATCA
TCAAATTATCATTCCAAGCGGTGACATGACTGTACAGGATAAAGATAGAATCTTTGTCACTGGTAACCGTGTCGATATGA
TACTCTTCCATAATTATTTTAAATCACGCGCCGTGAAGAGCCTTCTCATCGTTGGGGCAGGTAGAATTGCCTATTATCTA
CTTGGTATTCTCAAAGATAGTCGTATCGATACAAAAGTCATTGAAATCAATCCTGAAATCGCCAGCTTCTTTAGCGAGAA
ATTCCCAAATCTCTACATCGTTCAAGGAGATGGAACCGCAAAAGATATCCTGCTGGAAGAAAGTGCTCAACACTATGATG
CCGTTGCGACTCTAACAGGAGTCGATGAGGAAAATCTGATTACATCTATGTTCCTTGACAGGGTAGGTGTACAGAAAAAT
ATTACTAAGGTCAATCGTACCAGTCTCCTCGAGATTATCAATGCGCCTGATTTTTCAAGTATCATCACACCTAAAAGCAT
CGCTGTAGATACGATTATGCACTTTATTCGTGGTCGAGTTAATGCCCAGTATTCAGACCTTCAAGCCATGCACCATCTAG
CCAATGGCCAAATCGAAACCCTGCAATTCCATATCAAGGAAGCCAATAAAATGACTGCCAAACCTCTTTCTCAACTGAAA
TTGAAAAAAGAGGTTCTTATTGCAGCCATTATTCGAAAGGGCAAGACTATTTTCCCAACTGGGGAGGATATGTTGGAAGT
TGGAGACAAGCTCCTAGTAACAACCTTGTTGCCAAACATCACCAAGATTTATGACTTGATTGCGAGGTAA

Upstream 100 bases:

>100_bases
ATAGCAAATTTCCTACTAAAAGCTCTTGTTATTAGCTAGTAGGTGCATTTTTTCTTGAAAAAGGGTATGATAGTTACATC
ATGAAAAAGTAGGTTTTATT

Downstream 100 bases:

>100_bases
GAAATGAATAAAAGTATGATTCGTTACCTCCTTTCAAAGTTACTTTTGATTGAAGCTGTTCTCCTCTTGGTTCCTGTGGC
TATCGCTGTCTATTACCGTG

Product: potassium transporter peripheral membrane component

Products: NA

Alternate protein names: K(+)-uptake protein trkA homolog [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFDIIGILGNGADFAILEQASVQDCDIFIALTEHDEVNM
IAAVLAKKMGAKETIVRVRNPEYSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHNYFKSRAVKSLLIVGAGRIAYYL
LGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQGDGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKN
ITKVNRTSLLEIINAPDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMTAKPLSQLK
LKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR

Sequences:

>Translated_449_residues
MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFDIIGILGNGADFAILEQASVQDCDIFIALTEHDEVNM
IAAVLAKKMGAKETIVRVRNPEYSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHNYFKSRAVKSLLIVGAGRIAYYL
LGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQGDGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKN
ITKVNRTSLLEIINAPDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMTAKPLSQLK
LKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR
>Mature_449_residues
MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFDIIGILGNGADFAILEQASVQDCDIFIALTEHDEVNM
IAAVLAKKMGAKETIVRVRNPEYSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHNYFKSRAVKSLLIVGAGRIAYYL
LGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQGDGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKN
ITKVNRTSLLEIINAPDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMTAKPLSQLK
LKKEVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR

Specific function: Part of a potassium transport system [H]

COG id: COG0569

COG function: function code P; K+ transport systems, NAD-binding component

Gene ontology:

Cell location: Peripherally Bound To The Inner Side Of The Inner Membrane Via The Trkg And Trkh Proteins [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 RCK N-terminal domains [H]

Homologues:

Organism=Escherichia coli, GI1789685, Length=446, Percent_Identity=26.0089686098655, Blast_Score=154, Evalue=1e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR006037
- InterPro:   IPR003148 [H]

Pfam domain/function: PF02080 TrkA_C; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 49847; Mature: 49847

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFDIIGILGNGADFAILEQ
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHEEEEEECCCCCEEEEEC
ASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPEYSNSYFKEKNILGFSLIV
CCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCHHCCCCCEEEEEEE
NPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKSTSGLCQMPISDFRKKFGNVIV
CHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHCCCCCEECCHHHHHHHHCCEEE
CAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHNYFKSRAVKSLLIVGAGRIAYYL
EEEECCCEEEEECCCEEEECCCEEEEECCEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHH
LGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQGDGTAKDILLEESAQHYDAVATLTG
HHHHCCCCCCEEEEEECHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEEC
VDEENLITSMFLDRVGVQKNITKVNRTSLLEIINAPDFSSIITPKSIAVDTIMHFIRGRV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
NAQYSDLQAMHHLANGQIETLQFHIKEANKMTAKPLSQLKLKKEVLIAAIIRKGKTIFPT
CCCHHHHHHHHHHHCCCEEEEEEEEHHCCCHHHCHHHHHHHHHHHHHHHHHHCCCEECCC
GEDMLEVGDKLLVTTLLPNITKIYDLIAR
CHHHHHHCHHHHHHHHHCHHHHHHHHHCC
>Mature Secondary Structure
MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFDIIGILGNGADFAILEQ
CEEEEEECCHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHEEEEEECCCCCEEEEEC
ASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPEYSNSYFKEKNILGFSLIV
CCCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCHHCCCCCEEEEEEE
NPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKSTSGLCQMPISDFRKKFGNVIV
CHHHHHHHHHHHHHCCCCCCCHHHHCCCHHHHHHHHHHCCCCCEECCHHHHHHHHCCEEE
CAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHNYFKSRAVKSLLIVGAGRIAYYL
EEEECCCEEEEECCCEEEECCCEEEEECCEEEEEEHHHHHHHHHHHHHHHCCCHHHHHHH
LGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQGDGTAKDILLEESAQHYDAVATLTG
HHHHCCCCCCEEEEEECHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHEEEC
VDEENLITSMFLDRVGVQKNITKVNRTSLLEIINAPDFSSIITPKSIAVDTIMHFIRGRV
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCC
NAQYSDLQAMHHLANGQIETLQFHIKEANKMTAKPLSQLKLKKEVLIAAIIRKGKTIFPT
CCCHHHHHHHHHHHCCCEEEEEEEEHHCCCHHHCHHHHHHHHHHHHHHHHHHCCCEECCC
GEDMLEVGDKLLVTTLLPNITKIYDLIAR
CHHHHHHCHHHHHHHHHCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]