Click here to switch to the map view.

The map label for this gene is trkG [H]

Identifier: 225858322

GI number: 225858322

Start: 488723

End: 490162

Strand: Reverse

Name: trkG [H]

Synonym: SP70585_0542

Alternate gene names: 225858322

Gene position: 490162-488723 (Counterclockwise)

Preceding gene: 225858323

Following gene: 225858316

Centisome position: 22.44

GC content: 43.68

Gene sequence:

>1440_bases
ATGAATAAAAGTATGATTCGTTACCTCCTTTCAAAGTTACTTTTGATTGAAGCTGTTCTCCTCTTGGTTCCTGTGGCTAT
CGCTGTCTATTACCGTGAATCGAGCCAAGTCTTTACAGCCCTCTTTTCGACCATAGGGATTCTCGTATTGTTAGGCGGTT
CAGGGAGTTTACAGAAGCCAAAAAATCAACGGATTTATGCCAAGGAGGGAGTCTTGATCGTTGCCCTCTGTTGGATCCTT
TGGTCTTTCTTTGGTGGTCTCCCCTTTGTCTTTTCTGGGCAAATCCCCAGCCTTATTGATGCCTTTTTTGAAATTAGTTC
TGGGTTTACAACTACTGGAGCAAGTATTTTGAACGACGTTTCGGTTCTCAGCCGTTCCCTCCTCTTCTGGCGAAGTTTTA
CCCACTTGATTGGAGGGATGGGAGTGCTTGTTTTTGCACTTGCTATTATGGACAATGCCAAAAATAGCCACCTAGAGGTG
ATGAAGGCTGAGGTTCCAGGTCCTGTTTTTGGCAAGGTTGTATCCAAACTAAAAAACACTGCCCAGATTCTCTATCTCCT
TTATCTAGCTCTCTTCTCCCTCTTTGTCATCATCTATTATCTAGCTGGTATGCCTCTCTACGATAGTTTTGTCATTGCTA
TGGGGACAGCGGGAACTGGAGGCTTTACCGTCTATAACGACGGAATTGCCCACTATGGCAGCTCACTGATTACCTATCTG
GTCAGTATCGGAGTTCTGGTTTTTGGGGTAAATTTCAACCTCTACTACTACCTCATGCTCCGTCGCATCAAGGCCTTCTT
TGGTGACGAAGAACTTCGGGCTTACTTGGTCATTGTACTGGTTTCTACAGGCTTGATTAGCCTCAACACCCTCTACCTCT
ACCCAGGGTTTTCAAAGAGCTTTGAAATGACCTTCTTCCAGGTTTCCAACATCATTACAACAACTGGTTTTGGATATGGA
GATATTACCAACTGGCCCCTCTTCTCCCAGTTTATCCTCCTTTTCCTCATGGCAATCGGTGGCTCTGCTGGATCAACTGC
AGGTGGACTCAAGATTATTCGAGGCCTCATCCTTTCAAAAATTGCCAAAAACCAAATTTTGTCAATCCTATCGCCCCACC
GTGTTTTGACCCTCCATGTGAATCAAACGGTGATTGATAAAGATACCCAGCATAAGATTCTCAAGTACTTTGTCATCTAT
GCTATGATTTTGCTAGCGCTTATCTTTATTGTCAGCCTAGATAGCAATGATTTTCTGGTCGTGACCAGCGCTGTCTTTAG
CTGTTTCAATAATATCGGGCCTATTCTAGGAACCACTTCTAGTTTCTCAATCTTTAGTCCCATCTCAAAAATTCTCCTAT
CCTTTGCAATGATTGCAGGGCGCTTGGAGATTTACCCAATCCTCCTTCTCTTTATGAAGAGAACTTGGTCTAAGAGATAA

Upstream 100 bases:

>100_bases
CCCAACTGGGGAGGATATGTTGGAAGTTGGAGACAAGCTCCTAGTAACAACCTTGTTGCCAAACATCACCAAGATTTATG
ACTTGATTGCGAGGTAAGAA

Downstream 100 bases:

>100_bases
AATACAAAATCCCTCTTTTTACAATTGTGAAAGAGGGATTCTTATATTAAAAAAGGGGGAACGTTTTTAAATCCAAGCCT
ATCTGTAAGCAAAATCCTTA

Product: Trk transporter membrane-spanning protein - K+ transport

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFSTIGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWIL
WSFFGGLPFVFSGQIPSLIDAFFEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAGTGGFTVYNDGIAHYGSSLITYL
VSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYLVIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYG
DITNWPLFSQFILLFLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHKILKYFVIY
AMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISKILLSFAMIAGRLEIYPILLLFMKRTWSKR

Sequences:

>Translated_479_residues
MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFSTIGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWIL
WSFFGGLPFVFSGQIPSLIDAFFEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAGTGGFTVYNDGIAHYGSSLITYL
VSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYLVIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYG
DITNWPLFSQFILLFLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHKILKYFVIY
AMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISKILLSFAMIAGRLEIYPILLLFMKRTWSKR
>Mature_479_residues
MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFSTIGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWIL
WSFFGGLPFVFSGQIPSLIDAFFEISSGFTTTGASILNDVSVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAGTGGFTVYNDGIAHYGSSLITYL
VSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYLVIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYG
DITNWPLFSQFILLFLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHKILKYFVIY
AMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISKILLSFAMIAGRLEIYPILLLFMKRTWSKR

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=487, Percent_Identity=31.4168377823409, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI48994987, Length=472, Percent_Identity=31.3559322033898, Blast_Score=184, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52911; Mature: 52911

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFSTIGILVLLGGSGSLQKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCCCC
KNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAFFEISSGFTTTGASILNDV
CCCCEEHHCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHH
SVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEVMKAEVPGPVFGKVVSKLKNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHHHHHHHHHH
AQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAGTGGFTVYNDGIAHYGSSLITYL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEECCCCCCEEEECCCHHHHHHHHHHHH
VSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYLVIVLVSTGLISLNTLYLYPGFSKS
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHEEEEEEEECCCCCC
FEMTFFQVSNIITTTGFGYGDITNWPLFSQFILLFLMAIGGSAGSTAGGLKIIRGLILSK
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IAKNQILSILSPHRVLTLHVNQTVIDKDTQHKILKYFVIYAMILLALIFIVSLDSNDFLV
HHHHHHHHHHCCCEEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VTSAVFSCFNNIGPILGTTSSFSIFSPISKILLSFAMIAGRLEIYPILLLFMKRTWSKR
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFSTIGILVLLGGSGSLQKP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEECCCCCCCCC
KNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSLIDAFFEISSGFTTTGASILNDV
CCCCEEHHCCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHCCCCCCHHHHHHHH
SVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEVMKAEVPGPVFGKVVSKLKNT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEECCCCCHHHHHHHHHHHHH
AQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAGTGGFTVYNDGIAHYGSSLITYL
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHEEEECCCCCCEEEECCCHHHHHHHHHHHH
VSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYLVIVLVSTGLISLNTLYLYPGFSKS
HHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHEEEEEEEECCCCCC
FEMTFFQVSNIITTTGFGYGDITNWPLFSQFILLFLMAIGGSAGSTAGGLKIIRGLILSK
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
IAKNQILSILSPHRVLTLHVNQTVIDKDTQHKILKYFVIYAMILLALIFIVSLDSNDFLV
HHHHHHHHHHCCCEEEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
VTSAVFSCFNNIGPILGTTSSFSIFSPISKILLSFAMIAGRLEIYPILLLFMKRTWSKR
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]