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The map label for this gene is lepB

Identifier: 225858256

GI number: 225858256

Start: 426745

End: 427359

Strand: Reverse

Name: lepB

Synonym: SP70585_0474

Alternate gene names: 225858256

Gene position: 427359-426745 (Counterclockwise)

Preceding gene: 225858257

Following gene: 225858255

Centisome position: 19.56

GC content: 43.25

Gene sequence:

>615_bases
ATGAATTCATTTAAAAATTTCTTAAAAGAGTGGGGATTGTTCCTCCTAATTCTGTCATTACTAGCTTTAAGTCGTATCTT
TTTTTGGAGCAATGTTCGCGTAGAAGGACATTCCATGGATCCGACCCTAGCGGATGGCGAAATTCTCTTCGTTGTAAAGC
ACCTCCCTATTGACCGTTTTGATATCGTGGTGGCCCATGAGGAAGATGGCAATAAGGACATCGTCAAACGCGTGATTGGA
ATGCCTGGCGACACCATTCGTTACGAAAATGATAAACTCTACATCAATGACAAAGAAACGGACGAGCCTTATCTAGCAGA
CTATATCAAACGCTTCAAGGATGACAAACTCCAAAGCACTTACTCAGGCAAGGGCTTTGAAGGAAATAAAGGAACTTTCT
TTAGAAGTATCGCTCAAAAAGCCCAAGCCTTCACAGTTGATGTCAACTACAACACCAACTTTAGCTTTACTGTTCCAGAA
GGAGAATACCTTCTCCTCGGAGATGACCGCTTGGTTTCGAGCGACAGCCGCCACGTAGGTACCTTCAAAGCAAAAGATAT
CACAGGGGAAGCTAAATTCCGCTTCTGGCCAATCACCCGTATCGGAACATTTTAA

Upstream 100 bases:

>100_bases
CCAGATTTTGCAAGCCTATGGTATGCAGGGACTCAGCTTCTGCGCCAAATTGCACTTTAAAAACACTGAAAAAGCGAAAA
AACGCTTAGAAAGGTAAGTT

Downstream 100 bases:

>100_bases
GAAACCTAAGAGGCCGAGAATCACCAATCTCAGCCTCTTCTTCTATCGTGAGAAAATGATTGGTAACTATCTAAACTTAC
CAGAACAGAAACACCTCAAC

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLADGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIG
MPGDTIRYENDKLYINDKETDEPYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF

Sequences:

>Translated_204_residues
MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLADGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIG
MPGDTIRYENDKLYINDKETDEPYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF
>Mature_204_residues
MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLADGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIG
MPGDTIRYENDKLYINDKETDEPYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23472; Mature: 23472

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLADGEILFVVKHLPIDRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCCCCCE
DIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDEPYLADYIKRFKDDKLQST
EEEEEECCCCCHHHHHHHHCCCCCCEEEECCEEEECCCCCCCCHHHHHHHHHCCCHHHHH
YSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPEGEYLLLGDDRLVSSDSRHVG
CCCCCCCCCCCHHHHHHHHHCEEEEEEEECCCCEEEEECCCCEEEEECCEEECCCCCCCC
TFKAKDITGEAKFRFWPITRIGTF
EEEECCCCCCCEEEEEEHHCCCCC
>Mature Secondary Structure
MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLADGEILFVVKHLPIDRF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCEEEEEEECCCCCCE
DIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDEPYLADYIKRFKDDKLQST
EEEEEECCCCCHHHHHHHHCCCCCCEEEECCEEEECCCCCCCCHHHHHHHHHCCCHHHHH
YSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPEGEYLLLGDDRLVSSDSRHVG
CCCCCCCCCCCHHHHHHHHHCEEEEEEEECCCCEEEEECCCCEEEEECCEEECCCCCCCC
TFKAKDITGEAKFRFWPITRIGTF
EEEECCCCCCCEEEEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9272867; 11463916 [H]