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The map label for this gene is corA [H]

Identifier: 225858045

GI number: 225858045

Start: 217011

End: 217955

Strand: Reverse

Name: corA [H]

Synonym: SP70585_0247

Alternate gene names: 225858045

Gene position: 217955-217011 (Counterclockwise)

Preceding gene: 225858094

Following gene: 225858044

Centisome position: 9.98

GC content: 42.33

Gene sequence:

>945_bases
ATGAAACAAGTTTTTCTCTCTACAACAACTGAATTTAAAGAGATCGATACGCTTGAACCGGGTACTTGGATCAATCTCGT
CAATCCGACTCAAAATGAATCACTCGAAATCGCCAACACCTTCGATATTGATATTGCCGACCTTCGAGCACCGCTCGATG
CGGAAGAAATGTCTCGTATTACCATTGAAGACGAGTATACCCTGATTATCGTAGACGTGCCGGTCACGGAGGAAAGAAAT
AACCGCACCTACTACGTAACCATCCCGCTTGGTATTATCATCACTGAGGAAACCATTATCACTACGTGTTTGGAACCACT
ACCTGTCCTTGATGTCTTTATCAACCGTCGATTGCGTAATTTCTATACCTTCATGCGTTCACGTTTTATCTTTCAAATTC
TTTATCGCAATGCAGAGCTTTACCTAACAGCCCTTCGTTCAATCGACCGCAAGAGTGAACAAATCGAAAGTCAACTGCAT
CAATCAACTCGTAATGAAGAATTGATTGAGCTCATGGAATTGGAAAAAACTATCGTCTATTTCAAGGCCTCCCTCAAAAC
AAATGAGCGCGTGATTAAGAAATTGACCAGTTCAACCAGCAATATCAAGAAATACCTTGAGGACGAAGACCTGCTTGAAG
ACACCCTGATTGAAACCCAACAGGCCATCGAGATGGCAGATATTTATGGAAACGTCTTGCATTCTATGACAGAGACCTTT
GCCTCTATCATTTCTAACAACCAGAACAACATCATGAAAACCTTGGCCCTTGTGACCATCGTCATGTCCATCCCAACCAT
GGTCTTTTCTGCCTACGGGATGAACTTTAAGGATAATGAAATCCCCCTAAACGGAGAGCCAAATGCCTTCTGGTTAATCG
TCTTTATCGCCTTTGCTATGAGTGTCTCGCTCACTCTCTATCTCATCCATAAAAAATGGTTCTAA

Upstream 100 bases:

>100_bases
ATTATACCAAAAAAAGTGAGATTCTATTACCCAAAAGGCCGATTTTGTAGTATAATAGTACAGTGTGAAAAAATCTGAAA
AATGAGAAAGGATAAGGGAT

Downstream 100 bases:

>100_bases
GAGGAGTTCCTATGTCTCAAATTGATCTACAAAAATTAACTAAGAAAAACCAAGAGTTTGTCCACATTGCTACCCAACAA
TTCATCAAAGATGGGAAAAC

Product: magnesium and cobalt transporter

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDIDIADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERN
NRTYYVTIPLGIIITEETIITTCLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIETQQAIEMADIYGNVLHSMTETF
ASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNFKDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF

Sequences:

>Translated_314_residues
MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDIDIADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERN
NRTYYVTIPLGIIITEETIITTCLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIETQQAIEMADIYGNVLHSMTETF
ASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNFKDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF
>Mature_314_residues
MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDIDIADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERN
NRTYYVTIPLGIIITEETIITTCLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIETQQAIEMADIYGNVLHSMTETF
ASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNFKDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36447; Mature: 36447

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDIDIADLRAPLDAEEMSRI
CCEEEECCCCHHHHCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHCCCCCHHHHCEE
TIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITTCLEPLPVLDVFINRRLRN
EEECCEEEEEEECCCCCCCCCEEEEEEEEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHH
FYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLHQSTRNEELIELMELEKTIVY
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHE
FKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIETQQAIEMADIYGNVLHSMTETF
EECCCCCHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNFKDNEIPLNGEPNAFWLIVFIAFAM
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SVSLTLYLIHKKWF
HHHHHHEEEEECCC
>Mature Secondary Structure
MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDIDIADLRAPLDAEEMSRI
CCEEEECCCCHHHHCCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHCCCCCHHHHCEE
TIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITTCLEPLPVLDVFINRRLRN
EEECCEEEEEEECCCCCCCCCEEEEEEEEEEEEEECHHHHHHHHCCHHHHHHHHHHHHHH
FYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLHQSTRNEELIELMELEKTIVY
HHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHE
FKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIETQQAIEMADIYGNVLHSMTETF
EECCCCCHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNFKDNEIPLNGEPNAFWLIVFIAFAM
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHH
SVSLTLYLIHKKWF
HHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]