Click here to switch to the map view.

The map label for this gene is sdaAA

Identifier: 225857970

GI number: 225857970

Start: 144016

End: 144888

Strand: Reverse

Name: sdaAA

Synonym: SP70585_0168

Alternate gene names: 225857970

Gene position: 144888-144016 (Counterclockwise)

Preceding gene: 225857971

Following gene: 225857969

Centisome position: 6.63

GC content: 47.88

Gene sequence:

>873_bases
ATGTTTTATTCTATCAAAGAATTGGTCGAGCAAGCAGATCTGGACTTTCAAGGAAATGTCGCAGAACTCATGATTACAAC
AGAGTTTGAATTGACCGGTCGCGAACGTGAAGAAGTCTTCCTTCTCATGGAACGCAATCTGGAAGTTATGAAAGCCTCTG
TCCAACTTGGCCTCAATGAAAATAAATCTCGTAGTGGCCTGACAGGTGGAGATGCTGCCAAATTGGATCACTACATCGAA
AACGGAAAAACTCTGTCAGATTATACGATTCTCTCGGCTGCCCGAAATGCCATCGCAGTCAATGAACACAATGCCAAAAT
GGGCTTGGTCTGTGCCACTCCAACCGCTGGAAGTGCTGGCTGTCTGCCATCCGTTCTCACTGCTGCTATTGAAAAATTAG
ACCTCAGCCACGAGCAACAATTGGATTTCCTCTTTGCTGCTGGTGCCTTTGGACTAGTCATCGCAAACAATGCCTCCATC
TCAGGTGCTGAGGGTGGGTGTCAAGCTGAAGTTGGTTCAGCCTCTGCTATGAGTGCTGCCGCCTTGACTCTGGCTGCAGG
TGGAACACCTTATCAGGCCAGTCAAGCTATTGCCTTTGTCATTAAAAATATGCTAGGCCTCATCTGTGACCCTGTTGCAG
GTTTGGTCGAAGTTCCCTGTGTCAAACGTAATGCCATGGGAGCTAGCTTTGCTTTCATCGCAGCAGACATGGCCTTGGCA
GGTATCGAATCTAAAATCCCTGTGGATGAAGTGATCGATGCCATGTACCAAGTAGGAGCAAGCATGCCAACTGCCTTTCG
TGAAACAGCTGAAGGTGGACTCGCTACCACCCCTACTGGTCGTCGCCTCCAAAAAGAAATTTTCGGAGAATAA

Upstream 100 bases:

>100_bases
TGATTATCGAAGTTGACAGTCGCAACTGTGATGAGGCTATCGAAGAAATCCGAAAAATCCCTCATCTCCACAATGTCAAT
TTCTTTAAATAGGAGGAAGC

Downstream 100 bases:

>100_bases
GCTTATCAAATAGGAGAAACCATGACCTCTATCACAGCGATTTTTTTCGATTTGGATGGAACCCTCGTTGATAGTTCTAT
CGGGATTCACAATGCCTTTA

Product: L-serine dehydratase, iron-sulfur-dependent, alpha subunit

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIE
NGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALA
GIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE

Sequences:

>Translated_290_residues
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIE
NGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALA
GIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>Mature_290_residues
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIE
NGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALA
GIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=282, Percent_Identity=36.1702127659575, Blast_Score=147, Evalue=7e-37,
Organism=Escherichia coli, GI1789161, Length=265, Percent_Identity=38.8679245283019, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1788116, Length=181, Percent_Identity=45.3038674033149, Blast_Score=141, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 30379; Mature: 30379

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNE
CCCCHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCHHHEEEEHHCCHHHHHHHHHCCCCC
NKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAG
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCCC
CLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAA
CHHHHHHHHHHHHCCCCHHHHHHHEECCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHH
ALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALA
HHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
GIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCHHHHHHHHCCC
>Mature Secondary Structure
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNE
CCCCHHHHHHHCCCCCCCCEEEEEEEEEEEECCCCHHHEEEEHHCCHHHHHHHHHCCCCC
NKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAG
CCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCCC
CLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAA
CHHHHHHHHHHHHCCCCHHHHHHHEECCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHH
ALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALA
HHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
GIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCEECCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]