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The map label for this gene is fabH [H]

Identifier: 225686287

GI number: 225686287

Start: 451130

End: 452110

Strand: Reverse

Name: fabH [H]

Synonym: BMEA_B0465

Alternate gene names: 225686287

Gene position: 452110-451130 (Counterclockwise)

Preceding gene: 225686288

Following gene: 225686285

Centisome position: 38.14

GC content: 61.26

Gene sequence:

>981_bases
ATGACGGTCTGTTCCAGCAGGCTGGCCGGGTTCGGCCATGCCGTTCCCGACCGCAGGGTTGAAAATGCCGAGATCGAGGC
GCAACTGGGCCTGGAAACGGGCTGGATCGAACGGCGCACCGGCATCAGGTGCCGTCGCTGGGCCATGCCCGACGAAACGC
TGAGCCACCTTGCTGCAAGCGCGGCGGATATGGCACTGAGCGATGCCGGCATTGAGCGAAGCGATATTGCCCTGACCCTG
CTTGCCACCTCCACACCCGACCATCTGCTGCCGCCAACGGCTCCACTTCTGACGCACTGGCTGAACCTTCAAAATTCAGG
CGCGGCCGATCTGGCGGGAGCCTGCACCGGGTTTCTCTATGCGCTCGTTCTGGCTGATGGTTTTGTCAGGGCGCAGGGCA
AGCCCGTTCTGGTGGTTGCCGCCAATCTGCTCAGCCGCCGCATCAACATGGCGGAGCGCGCAAGTGCCGTGCTGTTTGGC
GATGCGGCAGGAGCCGTCGTTCTGGCGCCTTCCGCCAAGGCGAACAGTTTTCAAAGCCAGTTCATCACCAATGGCAGCCA
CTATGACCTGATCAAGGTTCCGGCGGGCGGGAGTGCGCGCGCCTACGCACCTGAACGCGATGCAAGCGAATTTTTAATGA
CGATGCAGGACGGGCGCGCCGTCTTCACAGAAGCCGTACGCATAATGTCCGGTGCGTCACAAAACGTGCTTGCATCCGCC
GCGATGCTTCCACAGGCAATCGACCGCTTCTTTCCGCATCAGGCCAATATCCGCATCGTAGACAAGGTTTGCGAAACAAT
TGGCGTTCCACGCGCGAAAGCTGCCTCAACACTTGAAACCTACGGTAATTCATCAGCCGCCACGATACCGCTCTCGCTTT
CGCTGGCAAACCTTGAGCAGCCCTTGCGGGAAGGCGAGCGCCTGCTTTTCGCCGCCGCTGGCGCAGGCATGACCGGCGGC
GCTGTGCTGATGCAGGTATGA

Upstream 100 bases:

>100_bases
TGATCTATGTGATGCCGCCCTATTGCGTGACAGCGGAAGAGCTTGACCGCACCTATGACGTCATTACGCAAGGCGTAGAT
ATGATTGCGGGGCAGACAAG

Downstream 100 bases:

>100_bases
AGCTTGTTTCCCCGCCACGCCCATATAACGGATTGGAAAATATCCTGTGGTGAGCCAGATTGCCAAACTACAGGATGATG
AAATCATATTTTTGTTTAAA

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MTVCSSRLAGFGHAVPDRRVENAEIEAQLGLETGWIERRTGIRCRRWAMPDETLSHLAASAADMALSDAGIERSDIALTL
LATSTPDHLLPPTAPLLTHWLNLQNSGAADLAGACTGFLYALVLADGFVRAQGKPVLVVAANLLSRRINMAERASAVLFG
DAAGAVVLAPSAKANSFQSQFITNGSHYDLIKVPAGGSARAYAPERDASEFLMTMQDGRAVFTEAVRIMSGASQNVLASA
AMLPQAIDRFFPHQANIRIVDKVCETIGVPRAKAASTLETYGNSSAATIPLSLSLANLEQPLREGERLLFAAAGAGMTGG
AVLMQV

Sequences:

>Translated_326_residues
MTVCSSRLAGFGHAVPDRRVENAEIEAQLGLETGWIERRTGIRCRRWAMPDETLSHLAASAADMALSDAGIERSDIALTL
LATSTPDHLLPPTAPLLTHWLNLQNSGAADLAGACTGFLYALVLADGFVRAQGKPVLVVAANLLSRRINMAERASAVLFG
DAAGAVVLAPSAKANSFQSQFITNGSHYDLIKVPAGGSARAYAPERDASEFLMTMQDGRAVFTEAVRIMSGASQNVLASA
AMLPQAIDRFFPHQANIRIVDKVCETIGVPRAKAASTLETYGNSSAATIPLSLSLANLEQPLREGERLLFAAAGAGMTGG
AVLMQV
>Mature_325_residues
TVCSSRLAGFGHAVPDRRVENAEIEAQLGLETGWIERRTGIRCRRWAMPDETLSHLAASAADMALSDAGIERSDIALTLL
ATSTPDHLLPPTAPLLTHWLNLQNSGAADLAGACTGFLYALVLADGFVRAQGKPVLVVAANLLSRRINMAERASAVLFGD
AAGAVVLAPSAKANSFQSQFITNGSHYDLIKVPAGGSARAYAPERDASEFLMTMQDGRAVFTEAVRIMSGASQNVLASAA
MLPQAIDRFFPHQANIRIVDKVCETIGVPRAKAASTLETYGNSSAATIPLSLSLANLEQPLREGERLLFAAAGAGMTGGA
VLMQV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=321, Percent_Identity=33.3333333333333, Blast_Score=174, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34342; Mature: 34210

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVCSSRLAGFGHAVPDRRVENAEIEAQLGLETGWIERRTGIRCRRWAMPDETLSHLAAS
CCCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCEEECCCCHHHHHHHHHH
AADMALSDAGIERSDIALTLLATSTPDHLLPPTAPLLTHWLNLQNSGAADLAGACTGFLY
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALVLADGFVRAQGKPVLVVAANLLSRRINMAERASAVLFGDAAGAVVLAPSAKANSFQSQ
HHHHHCCCEECCCCEEEEEHHHHHHHHHCHHHHCCEEEEECCCCEEEEECCCCCCHHHHH
FITNGSHYDLIKVPAGGSARAYAPERDASEFLMTMQDGRAVFTEAVRIMSGASQNVLASA
HHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHH
AMLPQAIDRFFPHQANIRIVDKVCETIGVPRAKAASTLETYGNSSAATIPLSLSLANLEQ
HHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEHHHHHH
PLREGERLLFAAAGAGMTGGAVLMQV
HHHHCCEEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure 
TVCSSRLAGFGHAVPDRRVENAEIEAQLGLETGWIERRTGIRCRRWAMPDETLSHLAAS
CCCCHHHCCCCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCEEECCCCHHHHHHHHHH
AADMALSDAGIERSDIALTLLATSTPDHLLPPTAPLLTHWLNLQNSGAADLAGACTGFLY
HHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALVLADGFVRAQGKPVLVVAANLLSRRINMAERASAVLFGDAAGAVVLAPSAKANSFQSQ
HHHHHCCCEECCCCEEEEEHHHHHHHHHCHHHHCCEEEEECCCCEEEEECCCCCCHHHHH
FITNGSHYDLIKVPAGGSARAYAPERDASEFLMTMQDGRAVFTEAVRIMSGASQNVLASA
HHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHH
AMLPQAIDRFFPHQANIRIVDKVCETIGVPRAKAASTLETYGNSSAATIPLSLSLANLEQ
HHHHHHHHHHCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEEEEEEHHHHHH
PLREGERLLFAAAGAGMTGGAVLMQV
HHHHCCEEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]