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The map label for this gene is xanB [H]

Identifier: 225686182

GI number: 225686182

Start: 326148

End: 327563

Strand: Reverse

Name: xanB [H]

Synonym: BMEA_B0346

Alternate gene names: 225686182

Gene position: 327563-326148 (Counterclockwise)

Preceding gene: 225686183

Following gene: 225686181

Centisome position: 27.63

GC content: 58.55

Gene sequence:

>1416_bases
ATGAGTTTCATACCGGTAATTATCAGCGGGGGATCGGGTTCAAGGCTTTGGCCGCTTTCGCGGGATGCACATCCAAAACC
CTTTATCAAACTGCCGGATGGCGAAACACTCATCGGCAAGACCTATGCGCGCGCTTCGCGCCTTGTAAACGCCGAACAGA
TCCTTACGGTTACGAACCGCGATTTTCTTTTCCTGACGCTCGACGCTTATGCGGCGGCAGGTGCCGCGCAGATGGAAAAC
ACTTTCCTTCTGGAGCCGCTTGGCCGCGACACCGCGCCCGCAGTGGCGCTTGCCGCCCTTCATGCCGCTGAAGCCTATGG
GCCGGATGCCACGCTTCTGGTCATGCCGGCCGATCACCTGATCGAGGATGAACAAGCCTTCGCGGAAGCGGTTGCGAAAG
CGCGCGCGCTTGCCGAGGCAGGGCGCATCGTCACCTTCGGCATTGTGCCGGATCGGCCCGAGACCGGCTTCGGCTATATC
GAAGTGCAAGGTACGGATGTTCAGCGATTTGTCGAAAAGCCGGATGAGGCCACCGCCCAGACCTATGTGGAAAGCGGACG
CTATTTCTGGAATTCCGGCATGTTCTGCTTCAAGGCATTGAGCATGATCGACGCCATGCAGCGTTACGCACCGCAGGTAC
TGGCAGGCGCTAGGGCTGCCCTCGCCCAGGCCCGGCGTGGCAATAACGGCGAGACCAAAACCCTTGAAATCGCCAGGGAC
GAGTTTGCCGCAACGCCTGCCATTTCCATCGACTACGCAGTCATGGAAAAGGCGGACAATATGGCCTGCGTGCCCGTTTC
CTGCGGCTGGTCGGATATCGGCTCATGGGCGGCGATGGCCGATCTCGTGACACCCGATGAAAACGGCAATCGCCTGCGCG
GAGAAACTGTTCTGGAAGATACGACCAACAGTTTCGTCCTTTCTGAAACCCGTCTGGTGAGCCTTGTCGGTGTGCATGAT
CTTCTCGTGGTTGACACGCCGGACGCCCTTCTCGTCGCTCATCGCGACAAAGCGCAGGAAGTACGCAGCGTTTTCAACAA
ATTGCGCAAGCAAGGTCATGAAGCTGCAAAGCTGCACCGCACAGCCCATCGCCCATGGGGCACCTATACCGTGCTGGAAG
AGGGCGACGGCTTCAAGATCAAACGGATCGAGGTAAAGCCAGGGCGGCGCCTCAGCCTTCAGGCCCATCACCACCGCTCC
GAACACTGGATCGTGGTGTCCGGCACGGCAAAGGTGACGAATGGCGACCGGGAAATCCTGCTCACCACCAATCAGTCAAC
CTATATTCCCTGCGGTTTCCGCCACCGGTTGGAAAATCCCGGTATTTTGCCCCTCGTCCTGATCGAGGTGCAGAGCGGCG
AATATCTCGGTGAAGACGACATCGTGCGCTATGACGATGTTTACGGACGCGTTTGA

Upstream 100 bases:

>100_bases
TGCGCTGCTATGTGGAATCTTCGGATGACACACAAGCCGCCAAGCTTCAGGCGCTTGGCTTGGAAATCGCACGCAAAGCA
CTAAAGGATGCGACGAGGCC

Downstream 100 bases:

>100_bases
AACATATTCAGCCAAATGCGAACCGGCTTTGGCATTCGGCCTATTGGGATTAAAACGCTCTATCTCTTTGTTTTTTCGCG
CGTCTTAACCCAAAACCGCT

Product: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSFIPVIISGGSGSRLWPLSRDAHPKPFIKLPDGETLIGKTYARASRLVNAEQILTVTNRDFLFLTLDAYAAAGAAQMEN
TFLLEPLGRDTAPAVALAALHAAEAYGPDATLLVMPADHLIEDEQAFAEAVAKARALAEAGRIVTFGIVPDRPETGFGYI
EVQGTDVQRFVEKPDEATAQTYVESGRYFWNSGMFCFKALSMIDAMQRYAPQVLAGARAALAQARRGNNGETKTLEIARD
EFAATPAISIDYAVMEKADNMACVPVSCGWSDIGSWAAMADLVTPDENGNRLRGETVLEDTTNSFVLSETRLVSLVGVHD
LLVVDTPDALLVAHRDKAQEVRSVFNKLRKQGHEAAKLHRTAHRPWGTYTVLEEGDGFKIKRIEVKPGRRLSLQAHHHRS
EHWIVVSGTAKVTNGDREILLTTNQSTYIPCGFRHRLENPGILPLVLIEVQSGEYLGEDDIVRYDDVYGRV

Sequences:

>Translated_471_residues
MSFIPVIISGGSGSRLWPLSRDAHPKPFIKLPDGETLIGKTYARASRLVNAEQILTVTNRDFLFLTLDAYAAAGAAQMEN
TFLLEPLGRDTAPAVALAALHAAEAYGPDATLLVMPADHLIEDEQAFAEAVAKARALAEAGRIVTFGIVPDRPETGFGYI
EVQGTDVQRFVEKPDEATAQTYVESGRYFWNSGMFCFKALSMIDAMQRYAPQVLAGARAALAQARRGNNGETKTLEIARD
EFAATPAISIDYAVMEKADNMACVPVSCGWSDIGSWAAMADLVTPDENGNRLRGETVLEDTTNSFVLSETRLVSLVGVHD
LLVVDTPDALLVAHRDKAQEVRSVFNKLRKQGHEAAKLHRTAHRPWGTYTVLEEGDGFKIKRIEVKPGRRLSLQAHHHRS
EHWIVVSGTAKVTNGDREILLTTNQSTYIPCGFRHRLENPGILPLVLIEVQSGEYLGEDDIVRYDDVYGRV
>Mature_470_residues
SFIPVIISGGSGSRLWPLSRDAHPKPFIKLPDGETLIGKTYARASRLVNAEQILTVTNRDFLFLTLDAYAAAGAAQMENT
FLLEPLGRDTAPAVALAALHAAEAYGPDATLLVMPADHLIEDEQAFAEAVAKARALAEAGRIVTFGIVPDRPETGFGYIE
VQGTDVQRFVEKPDEATAQTYVESGRYFWNSGMFCFKALSMIDAMQRYAPQVLAGARAALAQARRGNNGETKTLEIARDE
FAATPAISIDYAVMEKADNMACVPVSCGWSDIGSWAAMADLVTPDENGNRLRGETVLEDTTNSFVLSETRLVSLVGVHDL
LVVDTPDALLVAHRDKAQEVRSVFNKLRKQGHEAAKLHRTAHRPWGTYTVLEEGDGFKIKRIEVKPGRRLSLQAHHHRSE
HWIVVSGTAKVTNGDREILLTTNQSTYIPCGFRHRLENPGILPLVLIEVQSGEYLGEDDIVRYDDVYGRV

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=482, Percent_Identity=44.8132780082988, Blast_Score=397, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51713; Mature: 51582

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFIPVIISGGSGSRLWPLSRDAHPKPFIKLPDGETLIGKTYARASRLVNAEQILTVTNR
CCEEEEEEECCCCCEECCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHCCHHHEEEEECC
DFLFLTLDAYAAAGAAQMENTFLLEPLGRDTAPAVALAALHAAEAYGPDATLLVMPADHL
CEEEEEEEHHHCCCCHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHH
IEDEQAFAEAVAKARALAEAGRIVTFGIVPDRPETGFGYIEVQGTDVQRFVEKPDEATAQ
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHCCCCHHHHH
TYVESGRYFWNSGMFCFKALSMIDAMQRYAPQVLAGARAALAQARRGNNGETKTLEIARD
HHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
EFAATPAISIDYAVMEKADNMACVPVSCGWSDIGSWAAMADLVTPDENGNRLRGETVLED
HHCCCCCEEEEHHHHHCCCCEEEEEEECCCHHHCCHHHHHHCCCCCCCCCEECCCEEEEC
TTNSFVLSETRLVSLVGVHDLLVVDTPDALLVAHRDKAQEVRSVFNKLRKQGHEAAKLHR
CCCCEEEEHHHEEEEECEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHH
TAHRPWGTYTVLEEGDGFKIKRIEVKPGRRLSLQAHHHRSEHWIVVSGTAKVTNGDREIL
HHCCCCCCEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCEEEEEECCEEEECCCCEEE
LTTNQSTYIPCGFRHRLENPGILPLVLIEVQSGEYLGEDDIVRYDDVYGRV
EEECCCEEECCCHHHHCCCCCEEEEEEEEEECCCCCCCCCCEEECHHCCCC
>Mature Secondary Structure 
SFIPVIISGGSGSRLWPLSRDAHPKPFIKLPDGETLIGKTYARASRLVNAEQILTVTNR
CEEEEEEECCCCCEECCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHCCHHHEEEEECC
DFLFLTLDAYAAAGAAQMENTFLLEPLGRDTAPAVALAALHAAEAYGPDATLLVMPADHL
CEEEEEEEHHHCCCCHHCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCHHH
IEDEQAFAEAVAKARALAEAGRIVTFGIVPDRPETGFGYIEVQGTDVQRFVEKPDEATAQ
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECCCHHHHHCCCCHHHHH
TYVESGRYFWNSGMFCFKALSMIDAMQRYAPQVLAGARAALAQARRGNNGETKTLEIARD
HHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
EFAATPAISIDYAVMEKADNMACVPVSCGWSDIGSWAAMADLVTPDENGNRLRGETVLED
HHCCCCCEEEEHHHHHCCCCEEEEEEECCCHHHCCHHHHHHCCCCCCCCCEECCCEEEEC
TTNSFVLSETRLVSLVGVHDLLVVDTPDALLVAHRDKAQEVRSVFNKLRKQGHEAAKLHR
CCCCEEEEHHHEEEEECEEEEEEEECCCEEEEEECHHHHHHHHHHHHHHHCCHHHHHHHH
TAHRPWGTYTVLEEGDGFKIKRIEVKPGRRLSLQAHHHRSEHWIVVSGTAKVTNGDREIL
HHCCCCCCEEEEECCCCEEEEEEEECCCCEEEEEECCCCCCEEEEEECCEEEECCCCEEE
LTTNQSTYIPCGFRHRLENPGILPLVLIEVQSGEYLGEDDIVRYDDVYGRV
EEECCCEEECCCHHHHCCCCCEEEEEEEEEECCCCCCCCCCEEECHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]