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The map label for this gene is aglR [H]

Identifier: 225686147

GI number: 225686147

Start: 286813

End: 287829

Strand: Reverse

Name: aglR [H]

Synonym: BMEA_B0303

Alternate gene names: 225686147

Gene position: 287829-286813 (Counterclockwise)

Preceding gene: 225686154

Following gene: 225686145

Centisome position: 24.28

GC content: 60.08

Gene sequence:

>1017_bases
ATGAAACTCCGTGAATTCGCCAAACATATGGGCCTTTCCGCCACGACCGTCAGCCGGGCGCTGAGCGGCTATCCCGAAGT
GGCGGAAAGCACGCGCAAGCGCGTGATGGAAGAGGCCATCCGTCTTGGCTATCGCCCCAACGTGAATGCGGTGCGGCTGG
TAACGGGCCGCGCGGGCGCAATCGGCGTCGTGATGGGCCGCAACAGCGAGTTTCACTTTGCCGAATTCATGCGCGGCATG
GCCGAACGGCTGGGGCAGGACGAAGTGGACATTCTCGTCAGCCCCACCTCGCCGACCGGCAATGACGACGAGGTGCAGCT
TTGTCACCGGCTGGCAACGAGCGGACGGGTGGATGCCGTTATCGTCACTTCCCCCAGGCCGAATGATGAACGCATCCGCA
TGTTGCACAAGCTCGGCATGCCGTTTCTGGTCCACGGGCGTTCGCAGATCGACATTCCCCATGCATGGCTTGATATCGAC
AATGAGAGCGCGGTCTATCATTCCATCGCACATCTGCTCGATCTTGGCCACAAGCGGATTGCGATGATCAACGGGCGCCA
TGGCTTCACCTTCTCGCTGCACCGCGACGCTGGCTATCGTAAGGCGCTTGAAAGCCGGGGAATCGACTTTGATCCCGACC
TGGTGGAACATGGCGATTTCACCGATGAAATCGGCTATTGCCTCGCCCGCAAGCTTCTGGAACGCAATCCACGTCCAACG
GCATTCGTCGCAGGCTCCATGATGACCGCGCTCGGCATCTACCGTGCCGCCCGCTCCTTCGGCCTTACGATCGGCAAGGA
TATTTCCGTCATCGCCCATGACGACGTGATCTCGTTCCTCAGCGCCGGTAATATGGTGCCGTCGCTGACTGCGACACGCT
CTTCAATGCGCGCGGCTGGCAAGCGATCCGCCGACCTTTTGATGGATATCCTCGATGGGCGCGCGCCCACCGAAATCCAT
GAATTATGGCCGGTTGAACTGATCCTTCGCGAATCCGCCACCCGTGTTCCCGAATGA

Upstream 100 bases:

>100_bases
ACAATGAATGACCATAAATTACAGACACCATCCGCCCCAATTGTTAAATGCATGGAAGCGGCTATAATCCGCCGCCCCGC
CTGCCCAGTCTGAAAGCCAA

Downstream 100 bases:

>100_bases
GCCTGCTACCCATAGCCCATCAATAGATGGCAGCCCGGTTTTACTGGAAATGCTCTAAGCGGGGCGCGTAGGTTCTTCCT
GGTCGATGAGACTGGACGGC

Product: HTH-type transcriptional regulator RafR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKLREFAKHMGLSATTVSRALSGYPEVAESTRKRVMEEAIRLGYRPNVNAVRLVTGRAGAIGVVMGRNSEFHFAEFMRGM
AERLGQDEVDILVSPTSPTGNDDEVQLCHRLATSGRVDAVIVTSPRPNDERIRMLHKLGMPFLVHGRSQIDIPHAWLDID
NESAVYHSIAHLLDLGHKRIAMINGRHGFTFSLHRDAGYRKALESRGIDFDPDLVEHGDFTDEIGYCLARKLLERNPRPT
AFVAGSMMTALGIYRAARSFGLTIGKDISVIAHDDVISFLSAGNMVPSLTATRSSMRAAGKRSADLLMDILDGRAPTEIH
ELWPVELILRESATRVPE

Sequences:

>Translated_338_residues
MKLREFAKHMGLSATTVSRALSGYPEVAESTRKRVMEEAIRLGYRPNVNAVRLVTGRAGAIGVVMGRNSEFHFAEFMRGM
AERLGQDEVDILVSPTSPTGNDDEVQLCHRLATSGRVDAVIVTSPRPNDERIRMLHKLGMPFLVHGRSQIDIPHAWLDID
NESAVYHSIAHLLDLGHKRIAMINGRHGFTFSLHRDAGYRKALESRGIDFDPDLVEHGDFTDEIGYCLARKLLERNPRPT
AFVAGSMMTALGIYRAARSFGLTIGKDISVIAHDDVISFLSAGNMVPSLTATRSSMRAAGKRSADLLMDILDGRAPTEIH
ELWPVELILRESATRVPE
>Mature_338_residues
MKLREFAKHMGLSATTVSRALSGYPEVAESTRKRVMEEAIRLGYRPNVNAVRLVTGRAGAIGVVMGRNSEFHFAEFMRGM
AERLGQDEVDILVSPTSPTGNDDEVQLCHRLATSGRVDAVIVTSPRPNDERIRMLHKLGMPFLVHGRSQIDIPHAWLDID
NESAVYHSIAHLLDLGHKRIAMINGRHGFTFSLHRDAGYRKALESRGIDFDPDLVEHGDFTDEIGYCLARKLLERNPRPT
AFVAGSMMTALGIYRAARSFGLTIGKDISVIAHDDVISFLSAGNMVPSLTATRSSMRAAGKRSADLLMDILDGRAPTEIH
ELWPVELILRESATRVPE

Specific function: Probable regulatory protein for the binding-protein- dependent transport system for alpha-glucosides such as sucrose, maltose and trehalose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=338, Percent_Identity=27.2189349112426, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789068, Length=314, Percent_Identity=28.6624203821656, Blast_Score=104, Evalue=8e-24,
Organism=Escherichia coli, GI1787580, Length=319, Percent_Identity=23.1974921630094, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787948, Length=340, Percent_Identity=27.0588235294118, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786540, Length=343, Percent_Identity=25.3644314868805, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1788474, Length=337, Percent_Identity=27.0029673590504, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1790194, Length=319, Percent_Identity=25.0783699059561, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789202, Length=332, Percent_Identity=24.6987951807229, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787906, Length=266, Percent_Identity=27.4436090225564, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37419; Mature: 37419

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLREFAKHMGLSATTVSRALSGYPEVAESTRKRVMEEAIRLGYRPNVNAVRLVTGRAGA
CCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCE
IGVVMGRNSEFHFAEFMRGMAERLGQDEVDILVSPTSPTGNDDEVQLCHRLATSGRVDAV
EEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEE
IVTSPRPNDERIRMLHKLGMPFLVHGRSQIDIPHAWLDIDNESAVYHSIAHLLDLGHKRI
EEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEE
AMINGRHGFTFSLHRDAGYRKALESRGIDFDPDLVEHGDFTDEIGYCLARKLLERNPRPT
EEEECCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCC
AFVAGSMMTALGIYRAARSFGLTIGKDISVIAHDDVISFLSAGNMVPSLTATRSSMRAAG
EEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHC
KRSADLLMDILDGRAPTEIHELWPVELILRESATRVPE
CCHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKLREFAKHMGLSATTVSRALSGYPEVAESTRKRVMEEAIRLGYRPNVNAVRLVTGRAGA
CCHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCE
IGVVMGRNSEFHFAEFMRGMAERLGQDEVDILVSPTSPTGNDDEVQLCHRLATSGRVDAV
EEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCEE
IVTSPRPNDERIRMLHKLGMPFLVHGRSQIDIPHAWLDIDNESAVYHSIAHLLDLGHKRI
EEECCCCCHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEE
AMINGRHGFTFSLHRDAGYRKALESRGIDFDPDLVEHGDFTDEIGYCLARKLLERNPRPT
EEEECCCCEEEEEECCCHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCC
AFVAGSMMTALGIYRAARSFGLTIGKDISVIAHDDVISFLSAGNMVPSLTATRSSMRAAG
EEEHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHHHHHC
KRSADLLMDILDGRAPTEIHELWPVELILRESATRVPE
CCHHHHHHHHHCCCCCCHHHHHCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10400573; 11481430 [H]