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The map label for this gene is xylH [H]

Identifier: 225686115

GI number: 225686115

Start: 247753

End: 248949

Strand: Direct

Name: xylH [H]

Synonym: BMEA_B0268

Alternate gene names: 225686115

Gene position: 247753-248949 (Clockwise)

Preceding gene: 225686114

Following gene: 225686116

Centisome position: 20.9

GC content: 59.73

Gene sequence:

>1197_bases
GTGCGCCACGATAAAGGCGTTTCTGGCGCCATCCGCACCTTTATCGACCGGGTCAAGTCGGGCGATCTCGGTTCATTGCC
GGTCATTATTGGCCTTCTCATCATCTGGACAGTTTTCCAGACGTTGAACCCGGTTTTCCTTTCCAGCAACAACCTCGTGA
ACCTGCTATTCGATTGCTCGACCATCGGCGTCATTTCGCTCGGCATCGTCTGCGTATTGATGCTGGGTGAGATCGACCTT
TCGGTCGGTTCCATTAGTGGGCTTTCTTCGGCTATCATCGGTGTATTATGGGTCAATAATGGCTGGCCGGTGGGCGTCGC
CATCATTGCAGCACTTTGCGCAGGCGCACTGGCTGGCTTCCTCTACGCGCTCCTCTATAACCGCTTCAGCATGCCAAGCT
TCGTTTCCACACTGGCTGGGCTGCTCGCAGCCCTTGGGCTTCAGCTTTACCTCCTCGGCAATACAGGCTCCATCAATCTG
CCTTACGGTTCGTGGCTGGTCAGCTTCGGCCAGCTTCTGGTAATGCCGCGTCCGCTTTCTTATGCGCTGGCGCTGGTCGC
GGGACTTGCGATCTTTTTCACGGGTTTTCGCGCCGCGCAGCGCCGCCGCACGGCAGGGCTTTCCGCTCCCTCGGCTGCGG
GCATTGCGCTCAAAGCTTTGGTCATCACGCTCATTATCGGCTGTGGGGTATTTTATCTCAACCAGTCGCGCGGCGTGCCA
TGGATGTTTGCCCTGTTCGTGGCGCTGGTGATCGCGATGAACTATGCGCTTACGCGCACCAGATGGGGCCGCTGCGTGCA
GGCGGTTGGCGGCAATCGCGAGGCTGCGCGTCGTGCCGGCATCAATGTGAATTTCATCTATGTCTCGGCCTTCATGGCCT
GCTCCACACTCGCGGCTGCCGGTGGTATCATGGCGGCGGCGCGTCTGGCCTCATCCAGCCAGCAGGCAGGCACCGGTGAC
GTCAACCTCAATGCTATCGCGGCAGCGGTTATCGGCGGTACCAGCCTATTCGGCGGGCGCGGCAGCGCGTGGTCGGCCCT
GCTCGGTATTATCGTCATCCAGTCGATTGCGAGCGGTTTGACGCTTCTCGATCTGTCGTCTTCGCTTCGCTACATGATTA
CGGGTGCAGTGCTTGCCATCGCCGTGATTGTCGATTCCCTTGCCCGCCGTTCGCGCCAGTCGCACGGCCGCGCCTAG

Upstream 100 bases:

>100_bases
CCGTGCCGAAAGACGGCTGGCGCAGCACGATAATGCGCATGGCCGGGGGGAAGTCCGATGAACGGATATCAATACGCTGC
TTGATCGTCAGGATGTACGG

Downstream 100 bases:

>100_bases
GCTGTAGAGACGAATTAACTTATGGTTCGGCATGAACGAAAATGGTTCAGCTTTAGGAGTAAAACCGAAGATGGGGGGCA
ATCCATTGGCAAGGTTTTGC

Product: inner-membrane translocator

Products: ADP; phosphate; xylose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRHDKGVSGAIRTFIDRVKSGDLGSLPVIIGLLIIWTVFQTLNPVFLSSNNLVNLLFDCSTIGVISLGIVCVLMLGEIDL
SVGSISGLSSAIIGVLWVNNGWPVGVAIIAALCAGALAGFLYALLYNRFSMPSFVSTLAGLLAALGLQLYLLGNTGSINL
PYGSWLVSFGQLLVMPRPLSYALALVAGLAIFFTGFRAAQRRRTAGLSAPSAAGIALKALVITLIIGCGVFYLNQSRGVP
WMFALFVALVIAMNYALTRTRWGRCVQAVGGNREAARRAGINVNFIYVSAFMACSTLAAAGGIMAAARLASSSQQAGTGD
VNLNAIAAAVIGGTSLFGGRGSAWSALLGIIVIQSIASGLTLLDLSSSLRYMITGAVLAIAVIVDSLARRSRQSHGRA

Sequences:

>Translated_398_residues
MRHDKGVSGAIRTFIDRVKSGDLGSLPVIIGLLIIWTVFQTLNPVFLSSNNLVNLLFDCSTIGVISLGIVCVLMLGEIDL
SVGSISGLSSAIIGVLWVNNGWPVGVAIIAALCAGALAGFLYALLYNRFSMPSFVSTLAGLLAALGLQLYLLGNTGSINL
PYGSWLVSFGQLLVMPRPLSYALALVAGLAIFFTGFRAAQRRRTAGLSAPSAAGIALKALVITLIIGCGVFYLNQSRGVP
WMFALFVALVIAMNYALTRTRWGRCVQAVGGNREAARRAGINVNFIYVSAFMACSTLAAAGGIMAAARLASSSQQAGTGD
VNLNAIAAAVIGGTSLFGGRGSAWSALLGIIVIQSIASGLTLLDLSSSLRYMITGAVLAIAVIVDSLARRSRQSHGRA
>Mature_398_residues
MRHDKGVSGAIRTFIDRVKSGDLGSLPVIIGLLIIWTVFQTLNPVFLSSNNLVNLLFDCSTIGVISLGIVCVLMLGEIDL
SVGSISGLSSAIIGVLWVNNGWPVGVAIIAALCAGALAGFLYALLYNRFSMPSFVSTLAGLLAALGLQLYLLGNTGSINL
PYGSWLVSFGQLLVMPRPLSYALALVAGLAIFFTGFRAAQRRRTAGLSAPSAAGIALKALVITLIIGCGVFYLNQSRGVP
WMFALFVALVIAMNYALTRTRWGRCVQAVGGNREAARRAGINVNFIYVSAFMACSTLAAAGGIMAAARLASSSQQAGTGD
VNLNAIAAAVIGGTSLFGGRGSAWSALLGIIVIQSIASGLTLLDLSSSLRYMITGAVLAIAVIVDSLARRSRQSHGRA

Specific function: Part of the binding-protein-dependent transport system for D-xylose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4214

COG function: function code G; ABC-type xylose transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. AraH/rbsC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789992, Length=363, Percent_Identity=33.8842975206612, Blast_Score=152, Evalue=5e-38,
Organism=Escherichia coli, GI1790191, Length=158, Percent_Identity=40.5063291139241, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788896, Length=155, Percent_Identity=40.6451612903226, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790524, Length=152, Percent_Identity=36.1842105263158, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI145693152, Length=157, Percent_Identity=33.1210191082803, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787793, Length=362, Percent_Identity=27.9005524861878, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082395, Length=307, Percent_Identity=26.3843648208469, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 41404; Mature: 41404

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHDKGVSGAIRTFIDRVKSGDLGSLPVIIGLLIIWTVFQTLNPVFLSSNNLVNLLFDCS
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEHHHH
TIGVISLGIVCVLMLGEIDLSVGSISGLSSAIIGVLWVNNGWPVGVAIIAALCAGALAGF
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHH
LYALLYNRFSMPSFVSTLAGLLAALGLQLYLLGNTGSINLPYGSWLVSFGQLLVMPRPLS
HHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCEEECCHHHHHHHHHHHHCCCCCHH
YALALVAGLAIFFTGFRAAQRRRTAGLSAPSAAGIALKALVITLIIGCGVFYLNQSRGVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCH
WMFALFVALVIAMNYALTRTRWGRCVQAVGGNREAARRAGINVNFIYVSAFMACSTLAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHH
GGIMAAARLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAWSALLGIIVIQSIASGL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
TLLDLSSSLRYMITGAVLAIAVIVDSLARRSRQSHGRA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRHDKGVSGAIRTFIDRVKSGDLGSLPVIIGLLIIWTVFQTLNPVFLSSNNLVNLLFDCS
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEHHHH
TIGVISLGIVCVLMLGEIDLSVGSISGLSSAIIGVLWVNNGWPVGVAIIAALCAGALAGF
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHEEEEEECCCCCHHHHHHHHHHHHHHHHH
LYALLYNRFSMPSFVSTLAGLLAALGLQLYLLGNTGSINLPYGSWLVSFGQLLVMPRPLS
HHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEECCCEEECCHHHHHHHHHHHHCCCCCHH
YALALVAGLAIFFTGFRAAQRRRTAGLSAPSAAGIALKALVITLIIGCGVFYLNQSRGVP
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCH
WMFALFVALVIAMNYALTRTRWGRCVQAVGGNREAARRAGINVNFIYVSAFMACSTLAAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCEEEHHHHHHHHHHHHHHH
GGIMAAARLASSSQQAGTGDVNLNAIAAAVIGGTSLFGGRGSAWSALLGIIVIQSIASGL
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
TLLDLSSSLRYMITGAVLAIAVIVDSLARRSRQSHGRA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; xylose [Periplasm]; H2O [C]

Specific reaction: ATP + xylose [Periplasm] + H2O = ADP + phosphate + xylose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]