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The map label for this gene is waaA [H]

Identifier: 225686068

GI number: 225686068

Start: 200539

End: 201879

Strand: Direct

Name: waaA [H]

Synonym: BMEA_B0215

Alternate gene names: 225686068

Gene position: 200539-201879 (Clockwise)

Preceding gene: 225686067

Following gene: 225686069

Centisome position: 16.92

GC content: 61.07

Gene sequence:

>1341_bases
ATGAGCGAACGATGGGCGCGCAGCATATTGTCAGCCTACCGTTTTCTCGGCTCAGCCGCTTATCCTTTCGTGGGAAGCTA
CATCGCCTACCGTGCCTCGCGCGGCAAGGAAGACCGCTCCCGCCGTGGCGAACGCTATGGCAAGAGCGCGATTGCCCGCC
CGCAGGGGCCGGTTATCTGGGCGCACGCGGCAAGCGTGGGCGAAACGATTGCGCTTGTGCCGCTGGTCGAGCGTATTGTC
GCGACGGGCATCCATGTCGTGATGACGACGGGAACCGTCACCTCTGCCAAGGTGGTGGCAGATCAATTAGGTTCGCGGGT
CATTCATCAATATGCACCGCTCGACCTGCAACCGGCAGTCGATCATTTTCTCGATCACTGGAAGCCGGATCTCGTGATCG
GCTGCGAATCCGAAGTCTGGCCCGCCACGGTGCTGTCGCTCGGCAGCCGCCATATTCCGCATGTGCTGGTGAACGGGCGC
ATGTCCGACCGCTCCTTCGCTGCCTGGCAGAAGCGCCCAGCACTGGCCGAAGCCCTGTTTGAAAATTTCGCGCATGTGGT
GGCCCAGTCTGAGCTGGACGGTGAACGTTTCCGTGCTCTTGGCGCGCGCCCCGTCAGCGTGTCCGGCAATCTCAAGGTCG
ATACGCCGCCGCCGCCTTCTGATCCGCAAGCCATGTCGCTGATGCAGCGCCAGGTTGCAGGCCGGCGCACATGGGCGGCC
ATCTCCACCCATGACGGGGAGGAGGAAATTGCCGCCGAAGTGCATCAGATGCTGAAGATGCGCTATCCGCGCCTTATCAC
CATCATTGTTCCGCGCCACCCGGACCGCGCACCGGCCATTGAAGCGATGCTTGCCGCCAAGGGATTGAAGGTTGCCAGAA
GAAGCACGGGCCAGCCGATCGAAGCGGATACGGATGTGCTTCTGGGCGATACGATCGGCGAAATGGGGCTTTATCTGCAA
TTGACCGAGATTGCCTTCATCGGCAATTCGCTGACCAAGGAAGGCGGACACAACCCGCTGGAACCGGCCATGATGGGTAC
GGCCGTTCTGACGGGGCGCAATGTGCAGAATTTCCGCGAATCCTTCCAGCGCCTCATCAAGAATGGTGGCGCACGCATCG
TAAAAGACCGCAACATGCTGGCAGGCGCGATCAATTTCCTGTTCAACAACCCGCAACATCTGCGCGCCATGATCAATGCC
GGCGTGACCACGGTGCGCGACATGCGTGGTGCACTGGATCGCACGCTTGCCGCACTTGAACCATTCATCCAGCCGCTGGT
CTTGCAGGCGCAATTGCCGGGCAACCGGAACGAGCCTGCGTTCAGTCTGGACGAGCACTGA

Upstream 100 bases:

>100_bases
CCGATGCGGATGACGTGCAACTGGAAGAAAAGCGTGTGGAACTGACACGTCAGCTCAACAGGGCGACGGACAGGGCCTAT
GCAGCATTGGAGAAAGCGAA

Downstream 100 bases:

>100_bases
CCATGGCAAGCGAGGCGCCGCCTTTCTGGTGGGACGAACCTGATTGGCGCGCCCTTGCGCTGGCGCCAGCCGCCTGGATT
TACGGAAGGGTTTCCGGTCG

Product: 3-deoxy-D-manno-octulosonic-acid transferase

Products: NA

Alternate protein names: KDO transferase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSERWARSILSAYRFLGSAAYPFVGSYIAYRASRGKEDRSRRGERYGKSAIARPQGPVIWAHAASVGETIALVPLVERIV
ATGIHVVMTTGTVTSAKVVADQLGSRVIHQYAPLDLQPAVDHFLDHWKPDLVIGCESEVWPATVLSLGSRHIPHVLVNGR
MSDRSFAAWQKRPALAEALFENFAHVVAQSELDGERFRALGARPVSVSGNLKVDTPPPPSDPQAMSLMQRQVAGRRTWAA
ISTHDGEEEIAAEVHQMLKMRYPRLITIIVPRHPDRAPAIEAMLAAKGLKVARRSTGQPIEADTDVLLGDTIGEMGLYLQ
LTEIAFIGNSLTKEGGHNPLEPAMMGTAVLTGRNVQNFRESFQRLIKNGGARIVKDRNMLAGAINFLFNNPQHLRAMINA
GVTTVRDMRGALDRTLAALEPFIQPLVLQAQLPGNRNEPAFSLDEH

Sequences:

>Translated_446_residues
MSERWARSILSAYRFLGSAAYPFVGSYIAYRASRGKEDRSRRGERYGKSAIARPQGPVIWAHAASVGETIALVPLVERIV
ATGIHVVMTTGTVTSAKVVADQLGSRVIHQYAPLDLQPAVDHFLDHWKPDLVIGCESEVWPATVLSLGSRHIPHVLVNGR
MSDRSFAAWQKRPALAEALFENFAHVVAQSELDGERFRALGARPVSVSGNLKVDTPPPPSDPQAMSLMQRQVAGRRTWAA
ISTHDGEEEIAAEVHQMLKMRYPRLITIIVPRHPDRAPAIEAMLAAKGLKVARRSTGQPIEADTDVLLGDTIGEMGLYLQ
LTEIAFIGNSLTKEGGHNPLEPAMMGTAVLTGRNVQNFRESFQRLIKNGGARIVKDRNMLAGAINFLFNNPQHLRAMINA
GVTTVRDMRGALDRTLAALEPFIQPLVLQAQLPGNRNEPAFSLDEH
>Mature_445_residues
SERWARSILSAYRFLGSAAYPFVGSYIAYRASRGKEDRSRRGERYGKSAIARPQGPVIWAHAASVGETIALVPLVERIVA
TGIHVVMTTGTVTSAKVVADQLGSRVIHQYAPLDLQPAVDHFLDHWKPDLVIGCESEVWPATVLSLGSRHIPHVLVNGRM
SDRSFAAWQKRPALAEALFENFAHVVAQSELDGERFRALGARPVSVSGNLKVDTPPPPSDPQAMSLMQRQVAGRRTWAAI
STHDGEEEIAAEVHQMLKMRYPRLITIIVPRHPDRAPAIEAMLAAKGLKVARRSTGQPIEADTDVLLGDTIGEMGLYLQL
TEIAFIGNSLTKEGGHNPLEPAMMGTAVLTGRNVQNFRESFQRLIKNGGARIVKDRNMLAGAINFLFNNPQHLRAMINAG
VTTVRDMRGALDRTLAALEPFIQPLVLQAQLPGNRNEPAFSLDEH

Specific function: Essential step in lipopolysaccharides biosynthesis. Acts at transfer of 3-deoxy-D-mono octulonic acid (KDO) from CMP-KDO to a tetraacyldisaccharide 1,4'-bisphosphate precursor of lipid A (lipid IVA). Transfers a single molecule of KDO to lipid IVA [H]

COG id: COG1519

COG function: function code M; 3-deoxy-D-manno-octulosonic-acid transferase

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Escherichia coli, GI1790064, Length=410, Percent_Identity=36.5853658536585, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR007507 [H]

Pfam domain/function: PF00534 Glycos_transf_1; PF04413 Glycos_transf_N [H]

EC number: 2.-.-.-

Molecular weight: Translated: 48920; Mature: 48789

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERWARSILSAYRFLGSAAYPFVGSYIAYRASRGKEDRSRRGERYGKSAIARPQGPVIW
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHCCCCCCCEEE
AHAASVGETIALVPLVERIVATGIHVVMTTGTVTSAKVVADQLGSRVIHQYAPLDLQPAV
EECHHCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
DHFLDHWKPDLVIGCESEVWPATVLSLGSRHIPHVLVNGRMSDRSFAAWQKRPALAEALF
HHHHHCCCCCEEEECCCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCHHHHHHHH
ENFAHVVAQSELDGERFRALGARPVSVSGNLKVDTPPPPSDPQAMSLMQRQVAGRRTWAA
HHHHHHHHHHCCCHHHHHHCCCCEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEE
ISTHDGEEEIAAEVHQMLKMRYPRLITIIVPRHPDRAPAIEAMLAAKGLKVARRSTGQPI
EECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
EADTDVLLGDTIGEMGLYLQLTEIAFIGNSLTKEGGHNPLEPAMMGTAVLTGRNVQNFRE
CCCCCEEECCCHHHCCCEEEEHHHHHHCCHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHH
SFQRLIKNGGARIVKDRNMLAGAINFLFNNPQHLRAMINAGVTTVRDMRGALDRTLAALE
HHHHHHHCCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
PFIQPLVLQAQLPGNRNEPAFSLDEH
HHHHHHHEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SERWARSILSAYRFLGSAAYPFVGSYIAYRASRGKEDRSRRGERYGKSAIARPQGPVIW
CHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCHHHCCCCCCCEEE
AHAASVGETIALVPLVERIVATGIHVVMTTGTVTSAKVVADQLGSRVIHQYAPLDLQPAV
EECHHCCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
DHFLDHWKPDLVIGCESEVWPATVLSLGSRHIPHVLVNGRMSDRSFAAWQKRPALAEALF
HHHHHCCCCCEEEECCCCCCHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHCHHHHHHHH
ENFAHVVAQSELDGERFRALGARPVSVSGNLKVDTPPPPSDPQAMSLMQRQVAGRRTWAA
HHHHHHHHHHCCCHHHHHHCCCCEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCEEEE
ISTHDGEEEIAAEVHQMLKMRYPRLITIIVPRHPDRAPAIEAMLAAKGLKVARRSTGQPI
EECCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
EADTDVLLGDTIGEMGLYLQLTEIAFIGNSLTKEGGHNPLEPAMMGTAVLTGRNVQNFRE
CCCCCEEECCCHHHCCCEEEEHHHHHHCCHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHH
SFQRLIKNGGARIVKDRNMLAGAINFLFNNPQHLRAMINAGVTTVRDMRGALDRTLAALE
HHHHHHHCCCCEEEECCHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
PFIQPLVLQAQLPGNRNEPAFSLDEH
HHHHHHHEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952982; 7542800 [H]