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The map label for this gene is gltD [H]

Identifier: 225685922

GI number: 225685922

Start: 51639

End: 53093

Strand: Direct

Name: gltD [H]

Synonym: BMEA_B0059

Alternate gene names: 225685922

Gene position: 51639-53093 (Clockwise)

Preceding gene: 225685921

Following gene: 225685938

Centisome position: 4.36

GC content: 60.48

Gene sequence:

>1455_bases
ATGGGTAAGGTAACTGGTTTTCTTGAAATCGACCGGCAGGTGGCGAAGTACCAGCCGGCGTCGGATCGTATCCGCCACTT
CCGCGAATTCACCATCCCGATGACGGATGGCGAGGTGCAGAAGCAGGCGGCGCGCTGCATGGATTGCGGCATTCCATACT
GCCACGGGCCGACGGGCTGCCCGGTGCACAACCAGATCCCGGACTGGAACGATCTCGTCTATAACAACAACTGGGATCAG
GCGATCAGGAACCTGCACCTGACCAACAATTTCCCGGAATTCACCGGTCGTATCTGCCCGGCGCCTTGCGAGGAAGCCTG
CACGCTGAACCTTGAGGACATGCCGGTTGCAATCAAGACCGTGGAACAGGCGCTGGGCGACAAGGCCTATGAGCTTGGCT
ATATCGTGCCGCAGCCTGCCGCCAGCAAGACCGGCAAGTTGGTTGCCATCATCGGCTCCGGCCCGGCTGGCCTTGCGGCG
GCGCAGCAGCTTGCGCGTGCGGGCCACATGGTTGATGTCTATGAGCGCGAAAGCCGCCCCGGCGGATTGCTGCGCTATGG
CATTCCCGATTTCAAGATGGAAAAGCACCTGATCGACCGCCGCGTCGCGCAGATGGAAGGCGAGGGGGTGCGTTTCCATT
GCGGTGTGAATATCGGCGTCGACAAGCCGTTGCGCGGCCTTCTCGATACTTATGATGCGGTGCTTTATTGCGGCGGTTCG
GAAACCCCCCGCCCGGCGGGCATTCCCGGCGCCGATCTTGATGGTGTCCATGATGCCATGCCCTATCTCGTGCAGCAGAA
CCGCCGCGTTGGCCGCGAAAACATCGAGTCCGTCGCCTGGGCTTCGGTTCCGATTCTCGCAGGCGGCAAGCATGTCGTAG
TTGTCGGCGGCGGCGATACGGCATCGGATTGCGTCGGCACGGCTTTCCGTCAGGGCGCGGTCAATGTGACCCAGCTCGAT
ATCCGTCCGCAGCCGCCGGAAAAGGAAGACAAGCTCAGCGTCTGGCCCTATTGGGCGACCAAGATGCGCACTTCTTCCAG
CCAGGCGGAAGGCGCATCGCGTGAGTTTCAGGTCGCGACGCTGGAATTTATCGGCGAGGATGGACGCCTTACCCATGTGA
AGTGCTGTCAGGTCGATGAAAAGCGCAGGCCGATTGCCGGAACGGAATTCTTCATCAAGGCCGATCTGGCCTTCATCGCC
ATCGGCTTTGCCGGTCCTGTGGAAGACAGTGTGGTGAAGGAAATGGACGGGAAACTCGAAATCGCCACCGACCGGCGTGG
CTCGAAGTCCGTCAAGGCAAACGATCGTGATTATCGCACCAATGTCGACAAGCTCTATGCGGCGGGTGATATCCGTCGCG
GCCAGTCGCTGGTTGTCTGGGCGATCCGCGAAGGCCGTCAGGCAGCCCATGCTATTGATGCGGATTTGATGGGCAGTTCC
GTTTTGCCTCGTTGA

Upstream 100 bases:

>100_bases
CGGCGTGGCGGCTGAGTAAGAGCCATCGTTAAAACGCAGTGCTTGTGCGCCTGGGATGGCGCACGGCATCGCGAGCCTCG
CACAGCGAGAGGAGAATAAT

Downstream 100 bases:

>100_bases
GAGATGTGCATGGAAAGCCCGCCAAATGGCGGGCTTCATATTTTTTAGCTCTGCTTTTGCTTTAATTTCATGACCCAATA
GGCAATGCCCAGAAGCACGA

Product: glutamate synthase subunit beta

Products: NA

Alternate protein names: NADPH-GOGAT [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MGKVTGFLEIDRQVAKYQPASDRIRHFREFTIPMTDGEVQKQAARCMDCGIPYCHGPTGCPVHNQIPDWNDLVYNNNWDQ
AIRNLHLTNNFPEFTGRICPAPCEEACTLNLEDMPVAIKTVEQALGDKAYELGYIVPQPAASKTGKLVAIIGSGPAGLAA
AQQLARAGHMVDVYERESRPGGLLRYGIPDFKMEKHLIDRRVAQMEGEGVRFHCGVNIGVDKPLRGLLDTYDAVLYCGGS
ETPRPAGIPGADLDGVHDAMPYLVQQNRRVGRENIESVAWASVPILAGGKHVVVVGGGDTASDCVGTAFRQGAVNVTQLD
IRPQPPEKEDKLSVWPYWATKMRTSSSQAEGASREFQVATLEFIGEDGRLTHVKCCQVDEKRRPIAGTEFFIKADLAFIA
IGFAGPVEDSVVKEMDGKLEIATDRRGSKSVKANDRDYRTNVDKLYAAGDIRRGQSLVVWAIREGRQAAHAIDADLMGSS
VLPR

Sequences:

>Translated_484_residues
MGKVTGFLEIDRQVAKYQPASDRIRHFREFTIPMTDGEVQKQAARCMDCGIPYCHGPTGCPVHNQIPDWNDLVYNNNWDQ
AIRNLHLTNNFPEFTGRICPAPCEEACTLNLEDMPVAIKTVEQALGDKAYELGYIVPQPAASKTGKLVAIIGSGPAGLAA
AQQLARAGHMVDVYERESRPGGLLRYGIPDFKMEKHLIDRRVAQMEGEGVRFHCGVNIGVDKPLRGLLDTYDAVLYCGGS
ETPRPAGIPGADLDGVHDAMPYLVQQNRRVGRENIESVAWASVPILAGGKHVVVVGGGDTASDCVGTAFRQGAVNVTQLD
IRPQPPEKEDKLSVWPYWATKMRTSSSQAEGASREFQVATLEFIGEDGRLTHVKCCQVDEKRRPIAGTEFFIKADLAFIA
IGFAGPVEDSVVKEMDGKLEIATDRRGSKSVKANDRDYRTNVDKLYAAGDIRRGQSLVVWAIREGRQAAHAIDADLMGSS
VLPR
>Mature_483_residues
GKVTGFLEIDRQVAKYQPASDRIRHFREFTIPMTDGEVQKQAARCMDCGIPYCHGPTGCPVHNQIPDWNDLVYNNNWDQA
IRNLHLTNNFPEFTGRICPAPCEEACTLNLEDMPVAIKTVEQALGDKAYELGYIVPQPAASKTGKLVAIIGSGPAGLAAA
QQLARAGHMVDVYERESRPGGLLRYGIPDFKMEKHLIDRRVAQMEGEGVRFHCGVNIGVDKPLRGLLDTYDAVLYCGGSE
TPRPAGIPGADLDGVHDAMPYLVQQNRRVGRENIESVAWASVPILAGGKHVVVVGGGDTASDCVGTAFRQGAVNVTQLDI
RPQPPEKEDKLSVWPYWATKMRTSSSQAEGASREFQVATLEFIGEDGRLTHVKCCQVDEKRRPIAGTEFFIKADLAFIAI
GFAGPVEDSVVKEMDGKLEIATDRRGSKSVKANDRDYRTNVDKLYAAGDIRRGQSLVVWAIREGRQAAHAIDADLMGSSV
LPR

Specific function: NITROGEN METABOLISM, GLUTAMATE BIOSYNTHESIS. THE CATALYZED REACTION BRINGS TOGETHER THE NITROGEN AND CARBON METABOLISM. [C]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamate synthase family [H]

Homologues:

Organism=Homo sapiens, GI119943098, Length=464, Percent_Identity=24.5689655172414, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI1789606, Length=486, Percent_Identity=35.59670781893, Blast_Score=258, Evalue=6e-70,
Organism=Escherichia coli, GI1788811, Length=462, Percent_Identity=37.012987012987, Blast_Score=248, Evalue=5e-67,
Organism=Escherichia coli, GI87082180, Length=478, Percent_Identity=33.8912133891213, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1788468, Length=456, Percent_Identity=27.6315789473684, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1789243, Length=433, Percent_Identity=29.0993071593533, Blast_Score=116, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17570289, Length=503, Percent_Identity=42.544731610338, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI71984108, Length=297, Percent_Identity=27.6094276094276, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17543860, Length=161, Percent_Identity=39.7515527950311, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320030, Length=497, Percent_Identity=40.2414486921529, Blast_Score=373, Evalue=1e-104,
Organism=Drosophila melanogaster, GI28574881, Length=495, Percent_Identity=43.8383838383838, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24665539, Length=495, Percent_Identity=43.8383838383838, Blast_Score=407, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24665547, Length=495, Percent_Identity=43.8383838383838, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24665543, Length=495, Percent_Identity=43.8383838383838, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24640763, Length=464, Percent_Identity=25.6465517241379, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI18858217, Length=464, Percent_Identity=25.6465517241379, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17137178, Length=162, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR012285
- InterPro:   IPR006005
- InterPro:   IPR009051
- InterPro:   IPR016040
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.4.1.13 [H]

Molecular weight: Translated: 52972; Mature: 52841

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKVTGFLEIDRQVAKYQPASDRIRHFREFTIPMTDGEVQKQAARCMDCGIPYCHGPTGC
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
PVHNQIPDWNDLVYNNNWDQAIRNLHLTNNFPEFTGRICPAPCEEACTLNLEDMPVAIKT
CCCCCCCCCCCEEECCCHHHHHHEEECCCCCHHHCCCCCCCCCCHHHEECCCCCCHHHHH
VEQALGDKAYELGYIVPQPAASKTGKLVAIIGSGPAGLAAAQQLARAGHMVDVYERESRP
HHHHHCCCCEECCEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEHHCCCCC
GGLLRYGIPDFKMEKHLIDRRVAQMEGEGVRFHCGVNIGVDKPLRGLLDTYDAVLYCGGS
CCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCEEEEECCC
ETPRPAGIPGADLDGVHDAMPYLVQQNRRVGRENIESVAWASVPILAGGKHVVVVGGGDT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCEEEEEECCCC
ASDCVGTAFRQGAVNVTQLDIRPQPPEKEDKLSVWPYWATKMRTSSSQAEGASREFQVAT
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECEEHHHHCCCCCCCCCCCCCEEEEEE
LEFIGEDGRLTHVKCCQVDEKRRPIAGTEFFIKADLAFIAIGFAGPVEDSVVKEMDGKLE
EEEECCCCCEEEEEEECCCCCCCCCCCCEEEEEECEEEEEEECCCCCHHHHHHHCCCCEE
IATDRRGSKSVKANDRDYRTNVDKLYAAGDIRRGQSLVVWAIREGRQAAHAIDADLMGSS
EEECCCCCCCCCCCCCHHHCCHHHHEECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
VLPR
CCCC
>Mature Secondary Structure 
GKVTGFLEIDRQVAKYQPASDRIRHFREFTIPMTDGEVQKQAARCMDCGIPYCHGPTGC
CCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
PVHNQIPDWNDLVYNNNWDQAIRNLHLTNNFPEFTGRICPAPCEEACTLNLEDMPVAIKT
CCCCCCCCCCCEEECCCHHHHHHEEECCCCCHHHCCCCCCCCCCHHHEECCCCCCHHHHH
VEQALGDKAYELGYIVPQPAASKTGKLVAIIGSGPAGLAAAQQLARAGHMVDVYERESRP
HHHHHCCCCEECCEECCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEHHCCCCC
GGLLRYGIPDFKMEKHLIDRRVAQMEGEGVRFHCGVNIGVDKPLRGLLDTYDAVLYCGGS
CCEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCEEEEECCC
ETPRPAGIPGADLDGVHDAMPYLVQQNRRVGRENIESVAWASVPILAGGKHVVVVGGGDT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEECCCEEEEEECCCC
ASDCVGTAFRQGAVNVTQLDIRPQPPEKEDKLSVWPYWATKMRTSSSQAEGASREFQVAT
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEECEEHHHHCCCCCCCCCCCCCEEEEEE
LEFIGEDGRLTHVKCCQVDEKRRPIAGTEFFIKADLAFIAIGFAGPVEDSVVKEMDGKLE
EEEECCCCCEEEEEEECCCCCCCCCCCCEEEEEECEEEEEEECCCCCHHHHHHHCCCCEE
IATDRRGSKSVKANDRDYRTNVDKLYAAGDIRRGQSLVVWAIREGRQAAHAIDADLMGSS
EEECCCCCCCCCCCCCHHHCCHHHHEECCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCC
VLPR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 11029411 [H]