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The map label for this gene is ltaE [H]

Identifier: 225685919

GI number: 225685919

Start: 45114

End: 46163

Strand: Reverse

Name: ltaE [H]

Synonym: BMEA_B0056

Alternate gene names: 225685919

Gene position: 46163-45114 (Counterclockwise)

Preceding gene: 225685920

Following gene: 225685915

Centisome position: 3.89

GC content: 59.81

Gene sequence:

>1050_bases
GTGCATTTTGCGTCAGACAATTGGGCAGGCGCCCATCCAAAAATCGCCGAGAGCCTTTCGCTGCATGCAGCCGGTTTTGC
GGCAGCCTATGGCGCAAGCGAGATCGACAAACGTGTGGAACAACACTTCAATGAATTGTTCGAGCGTGAAGTGGCCGTTT
TCTTTGTCGGAACCGGTACGGCTGCCAATTCGCTGGCGCTGGCCAGCGTCAACCGGCCCGGCGGCGTTTCGCTGGTCCAC
CGCGAGGCGCATGTGATCGAGGATGGATGCGGCGCACCGGAATATTTCACCGGCGGCGCACGTCTCCACCCGATCGACGG
CGCTCTGGGCCGCATTGATCCCGAACTTCTGAAACGCGAATTGAAGCGTTTCAACCCCGCCTTCGTTCACGCGGGCCAGC
CCATGGCCGTCAGCATCACGCAGGCGACGGAAGTGGGTACGCTTTACCAGCCGGAGCATATCGCCACCATTTCGCAAATC
TGCCGCGATGCCGGACTGCCGCTACACATGGATGGCGCACGCTTTGCCAATGCGCTCGTGTCGCTTGATCTCACACCTGC
CGAAATGACATGGAAACTTGGCGTGGACATTGTGTCCTTCGGCGGCACCAAGAATGGCTGCTGGTGCGCCGAGGCGCTGG
TCTTCATGGACCCGGCCCGCGCCAAAGACCTGCCCTTCATCCGCAAGCGCGCAGCACAGCTTTTCTCCAAGACGCGCTTC
GTTGCCGCGCAGTTCGATGCCTATCTGCGTGACGATCTCTGGCGCGACCTTGCCCGCCATTCCAACGCGCTTGCTGCCCG
CCTTGCCAACCATATCCATGCATCAAGCCAGATGCGCCTTGCCTGGAAACCGGAAGCCAACGAGGTTTTCGCGATCATGA
AGCAATCGGTTTATGACCGTCTGCGCGATGCGGGTGCGGTATTCTACGACTGGAATCCTCCGCATTCGGAAGTGGGCCGC
ATCGGCGAGGGCGAGATTTTTGCCCGCTTTGTCACCAGCTTCGCCAATACGGAAGAAGAAGTGGACCGTTTCGGCGACAT
GATCGCCTGA

Upstream 100 bases:

>100_bases
CCGACATTTTTCGCGTAAGCCGAGCCTTAACCGCTTCTGTCAGACAGGCTATAGAAACAGCGACCCCGCAACTGCCCATT
TAACCGATCTGGAGGAACAC

Downstream 100 bases:

>100_bases
CACTCCTTGATATACTGAAGAACAAAAAGGCGGCACTTAAAGCGCCGCCTTTTCTTATTCATGATTAACCGAACTTAGAG
CGCATCCCGAAAAGTGTGAA

Product: Low specificity L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MHFASDNWAGAHPKIAESLSLHAAGFAAAYGASEIDKRVEQHFNELFEREVAVFFVGTGTAANSLALASVNRPGGVSLVH
REAHVIEDGCGAPEYFTGGARLHPIDGALGRIDPELLKRELKRFNPAFVHAGQPMAVSITQATEVGTLYQPEHIATISQI
CRDAGLPLHMDGARFANALVSLDLTPAEMTWKLGVDIVSFGGTKNGCWCAEALVFMDPARAKDLPFIRKRAAQLFSKTRF
VAAQFDAYLRDDLWRDLARHSNALAARLANHIHASSQMRLAWKPEANEVFAIMKQSVYDRLRDAGAVFYDWNPPHSEVGR
IGEGEIFARFVTSFANTEEEVDRFGDMIA

Sequences:

>Translated_349_residues
MHFASDNWAGAHPKIAESLSLHAAGFAAAYGASEIDKRVEQHFNELFEREVAVFFVGTGTAANSLALASVNRPGGVSLVH
REAHVIEDGCGAPEYFTGGARLHPIDGALGRIDPELLKRELKRFNPAFVHAGQPMAVSITQATEVGTLYQPEHIATISQI
CRDAGLPLHMDGARFANALVSLDLTPAEMTWKLGVDIVSFGGTKNGCWCAEALVFMDPARAKDLPFIRKRAAQLFSKTRF
VAAQFDAYLRDDLWRDLARHSNALAARLANHIHASSQMRLAWKPEANEVFAIMKQSVYDRLRDAGAVFYDWNPPHSEVGR
IGEGEIFARFVTSFANTEEEVDRFGDMIA
>Mature_349_residues
MHFASDNWAGAHPKIAESLSLHAAGFAAAYGASEIDKRVEQHFNELFEREVAVFFVGTGTAANSLALASVNRPGGVSLVH
REAHVIEDGCGAPEYFTGGARLHPIDGALGRIDPELLKRELKRFNPAFVHAGQPMAVSITQATEVGTLYQPEHIATISQI
CRDAGLPLHMDGARFANALVSLDLTPAEMTWKLGVDIVSFGGTKNGCWCAEALVFMDPARAKDLPFIRKRAAQLFSKTRF
VAAQFDAYLRDDLWRDLARHSNALAARLANHIHASSQMRLAWKPEANEVFAIMKQSVYDRLRDAGAVFYDWNPPHSEVGR
IGEGEIFARFVTSFANTEEEVDRFGDMIA

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 38365; Mature: 38365

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFASDNWAGAHPKIAESLSLHAAGFAAAYGASEIDKRVEQHFNELFEREVAVFFVGTGT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEECCC
AANSLALASVNRPGGVSLVHREAHVIEDGCGAPEYFTGGARLHPIDGALGRIDPELLKRE
CCCCEEEEECCCCCCCEEEEHHHHHHHCCCCCCCEECCCCEEECCCCCHHCCCHHHHHHH
LKRFNPAFVHAGQPMAVSITQATEVGTLYQPEHIATISQICRDAGLPLHMDGARFANALV
HHHCCCCEEECCCCEEEEEECHHCCCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHH
SLDLTPAEMTWKLGVDIVSFGGTKNGCWCAEALVFMDPARAKDLPFIRKRAAQLFSKTRF
HCCCCCHHEEEEECCEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
VAAQFDAYLRDDLWRDLARHSNALAARLANHIHASSQMRLAWKPEANEVFAIMKQSVYDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
LRDAGAVFYDWNPPHSEVGRIGEGEIFARFVTSFANTEEEVDRFGDMIA
HHHCCEEEECCCCCHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MHFASDNWAGAHPKIAESLSLHAAGFAAAYGASEIDKRVEQHFNELFEREVAVFFVGTGT
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEECCC
AANSLALASVNRPGGVSLVHREAHVIEDGCGAPEYFTGGARLHPIDGALGRIDPELLKRE
CCCCEEEEECCCCCCCEEEEHHHHHHHCCCCCCCEECCCCEEECCCCCHHCCCHHHHHHH
LKRFNPAFVHAGQPMAVSITQATEVGTLYQPEHIATISQICRDAGLPLHMDGARFANALV
HHHCCCCEEECCCCEEEEEECHHCCCCCCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHH
SLDLTPAEMTWKLGVDIVSFGGTKNGCWCAEALVFMDPARAKDLPFIRKRAAQLFSKTRF
HCCCCCHHEEEEECCEEEECCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
VAAQFDAYLRDDLWRDLARHSNALAARLANHIHASSQMRLAWKPEANEVFAIMKQSVYDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
LRDAGAVFYDWNPPHSEVGRIGEGEIFARFVTSFANTEEEVDRFGDMIA
HHHCCEEEECCCCCHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]