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The map label for this gene is purQ

Identifier: 225852353

GI number: 225852353

Start: 838969

End: 839640

Strand: Reverse

Name: purQ

Synonym: BMEA_A0879

Alternate gene names: 225852353

Gene position: 839640-838969 (Counterclockwise)

Preceding gene: 225852354

Following gene: 225852352

Centisome position: 39.5

GC content: 60.57

Gene sequence:

>672_bases
ATGAAATCCGCAGTCATTCTTCTTCCCGGCCTCAACCGTAATCGCGATATGATCGCGGCACTCACCAAGATCACCGGGCA
GGCTCCTGTGACGGTCTGGCAGACTGACACCAGCATTCCAGACGATGTGGATCTGATCCTTATTCCCGGCGGTTTTTCCT
ATGGTGACTATCTGCGCTGCGGCGCAATTGCCGCGCGTATGCCGGTGATGCAGGCCGTGCGCGAGAAGGCCGACAAGGGC
GTGATGGTCATGGGCGTGTGCAACGGCTTCCAGATCCTCCTTGAGGCCGGGCTTCTGCCGGGCGCGCTGATGCGCAATGC
CTCGCTGAAATTCGTCTGCCGCGAAGTGAAGCTCGAAGTAACCAACGCCAACACGTCGTTCACACGCGGTTACAAGCCGG
GCCAGATCATCCGCTGCCCGGTCGCGCATCACGACGGCAATTATTTCGCCGACGCCGAAACGCTGAAGCGTCTCGAAGGC
GAAGGCCAGGTCGTGTTCCGCTATGCCGAAGGCACCAACCCGAACGGATCGGTCAACGACATTGCCGGTATCGTCAATGC
GCGCGGCAATGTGCTGGGCATGATGCCGCATCCGGAAAACCTGATCGAAGCCGCCCATGGCGGCGATGACGGCCGGGCGC
TTTTTGCAGGCGCACTCGGCATCACAGCCTGA

Upstream 100 bases:

>100_bases
GAAGCGGACCTCAAGGCCATGTGCGAGAAGCTGCTCGCCAACACCGTGATTGAAGATTATTCTATCGCCATCGCCTGAGC
CCAAAAAGGAAGCAGACGCC

Downstream 100 bases:

>100_bases
CGGATCTTGCATATATGAAAACGGGCGGCCCAATCGGAGCCGCCTTTTTTATTGCGCATGCTTCATCTCAAAACTGCACT
GGCAAAGCATCTGTTTTCAT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MKSAVILLPGLNRNRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRCGAIAARMPVMQAVREKADKG
VMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEG
EGQVVFRYAEGTNPNGSVNDIAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA

Sequences:

>Translated_223_residues
MKSAVILLPGLNRNRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRCGAIAARMPVMQAVREKADKG
VMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEG
EGQVVFRYAEGTNPNGSVNDIAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA
>Mature_223_residues
MKSAVILLPGLNRNRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRCGAIAARMPVMQAVREKADKG
VMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEVTNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEG
EGQVVFRYAEGTNPNGSVNDIAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain

Homologues:

Organism=Escherichia coli, GI48994899, Length=227, Percent_Identity=30.8370044052863, Blast_Score=74, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6321498, Length=203, Percent_Identity=32.512315270936, Blast_Score=75, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24582111, Length=232, Percent_Identity=30.6034482758621, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582109, Length=232, Percent_Identity=30.6034482758621, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17137292, Length=232, Percent_Identity=30.6034482758621, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PURQ_BRUA2 (Q2YNG3)

Other databases:

- EMBL:   AM040264
- RefSeq:   YP_414288.1
- ProteinModelPortal:   Q2YNG3
- SMR:   Q2YNG3
- STRING:   Q2YNG3
- GeneID:   3787544
- GenomeReviews:   AM040264_GR
- KEGG:   bmf:BAB1_0860
- eggNOG:   COG0047
- HOGENOM:   HBG302712
- OMA:   HPENHVE
- ProtClustDB:   PRK03619
- BioCyc:   BMEL359391:BAB1_0860-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00421
- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075
- PIRSF:   PIRSF001586
- TIGRFAMs:   TIGR01737

Pfam domain/function: PF07685 GATase_3

EC number: =6.3.5.3

Molecular weight: Translated: 23768; Mature: 23768

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS51273 GATASE_TYPE_1

Important sites: ACT_SITE 87-87 ACT_SITE 197-197 ACT_SITE 199-199

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSAVILLPGLNRNRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRC
CCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHH
GAIAARMPVMQAVREKADKGVMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEV
HHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCHHHHCCCCCEEEEEEEEEEE
TNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEGEGQVVFRYAEGTNPNGSVND
ECCCCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCCHHH
IAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA
HHHHHCCCCCEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MKSAVILLPGLNRNRDMIAALTKITGQAPVTVWQTDTSIPDDVDLILIPGGFSYGDYLRC
CCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCHHHH
GAIAARMPVMQAVREKADKGVMVMGVCNGFQILLEAGLLPGALMRNASLKFVCREVKLEV
HHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCCHHHHCCCCCEEEEEEEEEEE
TNANTSFTRGYKPGQIIRCPVAHHDGNYFADAETLKRLEGEGQVVFRYAEGTNPNGSVND
ECCCCCCCCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCCCHHH
IAGIVNARGNVLGMMPHPENLIEAAHGGDDGRALFAGALGITA
HHHHHCCCCCEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA