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The map label for this gene is pleC [H]

Identifier: 225852141

GI number: 225852141

Start: 629359

End: 631710

Strand: Reverse

Name: pleC [H]

Synonym: BMEA_A0654

Alternate gene names: 225852141

Gene position: 631710-629359 (Counterclockwise)

Preceding gene: 225852142

Following gene: 225852140

Centisome position: 29.72

GC content: 60.63

Gene sequence:

>2352_bases
ATGGCGAGCACCGACGCGTATGGCGCGCCGGCGGGGACGCATTGCGAATCCGGCCGGAAAAAGAGGAAAGGCAGGCTTTC
GGGCCATGTCAGCCTTCTCGCGGGGCCGGCTTATAGCAAATTCATCGTCATAGAACCCATCCTGCGCCGCCTCGTCCCTA
CACTCATCATCATTTTCCTGATTATTCTCGGCGTGGCCCGCGTTTTCTCGCTTTTGGCCTGGCGCGACGATATTGAATTG
CAGCACAAGGCTGCTCTTTCCGGCGCGACGGCGCATCTGGCGCAGATGATCGAGCGTGTCGCCAACGGGATCGAAACAGG
CGCACAGCTTTCCGCCAAGGATTTGCAGGACGCCATGACGGAGCTTCGCTCGCGCGGCCTTACCTCGTCCGGCATGACCA
TCGCCATCGTGGATGCGCAATCCATGATTAAAGCCGCATCTGGCCCAGCCGGGATCGCTGGCAGCCAGATCGACACCATT
CTGGGGGATGCACAGCCGCTGTTCCTTTTTGCCGAGCGCGCCGGTGTGCTCAGGGTTGTATTGCAGGGCGAAGCCGCCTT
CGGCGCGCTGGCCAAGCCAATGACCGCGCCCTATTCCATCATTGCGGTCGAACCGGAAAGCACCATCTTTGCCGAGTGGA
AAAGGGCTGTATCGCTCAATGTGACGCTTTTTGCCGGCACGATCGGCGTGATGTTCGCAATTCTCTATGCCTATTTCAGC
CAGGCCGCGCGGGCACGCGAGGCCGACGATCTCTCCGGGCAGATACAGCGCCGCATCGACATGGCGCTGGCGCGCGGGCG
TTGCGGCCTTTGGGATTGGGACATGGCGCGCGGGCGCATCTACTGGTCACGCTCCATGTATGAAATGCTGGGCTATGAAG
CGCAGGATGCCGTGCTGCCCTTTGGCGATGTGGCGGCGATCATCAATGAGGAAGACGGCGATCTCTACTCCATCGCCGAA
CAGGCGGCGGCTGGCGATATTTCACATGTGGACCGGGTCTTCCGTATGCGCCACGCGGACGGTTCATGGGTCTGGATGCG
TGTTCGCGCCGAAATCGCCAGCGAGGGCGACCTTCATCTGGTCGGCATCGCCTTCGATGTCAGTGAGCAGCATCGCTTCG
CGCAGCAGACCGCCGAAGCCGACATGCGCATTCGTGAGGCAATCGAGAATATTTCGGAAGCCTTCGTTCTCTGGGACGCG
AATAACCGCCTGGTGATGGCGAATTCCAAGTTCAGCGAATATGCGGGCCTGCCGGTCTGGACGCTGAAACCGGGCGTGCC
ACGCAACGAAGTGGACGCGCATACCCGCCCCTTCACCTTCGAGCGCCGCATGGCGAACGAACACAACCGCGCAGGCGGCC
AGACTTTCGAGCGGCAGTTGAGCGACGGGCGCTGGCTACAGGTCAACGAACGGCGCACACAAGATGGCGGCATGGTCTCC
ATCGGCACGGACATTACCCAGCTCAAGCTGCATCAGGAGCGCCTTGTGGATAGCGAGCGCCGCCTGATGGCGACGGTTCA
CGATCTTTCCATCGCCCGAAAGGGTGAGCGCGACCGGGTGCGCGAGCTTTCCGAACTGGCGCGCAAATACAGCCTTGAAA
AGGAGCGCGCGGAAGCGGCCAACCGGGCCAAATCGGAATTCCTCGCCAATATGTCCCACGAGTTGCGCACGCCGCTCAAT
GCGATCATCGGCTTCTCGGAAATGATCCAGGCAGGCACGTTCGGCCCGCTGGGTTCCGACCGCTATGAGGAATATATCAA
CGACATCCACACCAGCGGCAACTTCCTGCTCAACGTCATCAATGACATTCTGGATATGTCGAAGATCGAGGCCGGGCATT
TCTCGCTCGATCGCGAGGAAATCGATCTCTGCCCGCTCATCAATGAAACGGTGCGGATAATCTCGCTCCAGGCCGAAGAG
AAGAACATCGCGGTCGAAACGCGTATCGAAGACGCGATGGAGCTTTATGCAGACCGCCGCGCGATCAAGCAGGTGCTCAT
CAACCTTCTCTCCAATGCGGTGAAGTTCACCTCTTATGGTGGCCGGATCACAGTGCGCGCCCGTAAGACCGGCGCCGCCC
TGTTCATGACCATTCAGGATACCGGCGTCGGCATTCCGAAATCCGCACTGCGCAAGATCGGCCAGCCCTTCGAGCAGGTG
GAAAACCAGTTCACCAAAACCCATACCGGTTCGGGGCTTGGCCTTGCCATCTCCCGCTCACTGGCAGAGCTGCATGGCGG
CTGGCTGCGCATTCGATCCACCGAGAGGGTCGGCACGGTGGTTTCAGTCTGCATCCCGGATCGCAATCCCGCGCCCAATG
CAGGGCACGACGCCCGGACCCACGCTGCTTAG

Upstream 100 bases:

>100_bases
ATCATATTTTGAACCAGGATTTCAGTTCATACAGTTCTGCGTAGAAGAGTGTTTCATGCGCTTCGCAGGGCTGTTCCATA
GATTCAAGAGGGGCCGAGAG

Downstream 100 bases:

>100_bases
TACGTTTCGAGCCATAAGTGTGAAACGGTTTTGCGGGAAAAGCTTTAGCCGCGGCCGGTCTGTCACAAACGTAATATTAA
ATAATTACACAAGATATACA

Product: PAS domain S-box-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MASTDAYGAPAGTHCESGRKKRKGRLSGHVSLLAGPAYSKFIVIEPILRRLVPTLIIIFLIILGVARVFSLLAWRDDIEL
QHKAALSGATAHLAQMIERVANGIETGAQLSAKDLQDAMTELRSRGLTSSGMTIAIVDAQSMIKAASGPAGIAGSQIDTI
LGDAQPLFLFAERAGVLRVVLQGEAAFGALAKPMTAPYSIIAVEPESTIFAEWKRAVSLNVTLFAGTIGVMFAILYAYFS
QAARAREADDLSGQIQRRIDMALARGRCGLWDWDMARGRIYWSRSMYEMLGYEAQDAVLPFGDVAAIINEEDGDLYSIAE
QAAAGDISHVDRVFRMRHADGSWVWMRVRAEIASEGDLHLVGIAFDVSEQHRFAQQTAEADMRIREAIENISEAFVLWDA
NNRLVMANSKFSEYAGLPVWTLKPGVPRNEVDAHTRPFTFERRMANEHNRAGGQTFERQLSDGRWLQVNERRTQDGGMVS
IGTDITQLKLHQERLVDSERRLMATVHDLSIARKGERDRVRELSELARKYSLEKERAEAANRAKSEFLANMSHELRTPLN
AIIGFSEMIQAGTFGPLGSDRYEEYINDIHTSGNFLLNVINDILDMSKIEAGHFSLDREEIDLCPLINETVRIISLQAEE
KNIAVETRIEDAMELYADRRAIKQVLINLLSNAVKFTSYGGRITVRARKTGAALFMTIQDTGVGIPKSALRKIGQPFEQV
ENQFTKTHTGSGLGLAISRSLAELHGGWLRIRSTERVGTVVSVCIPDRNPAPNAGHDARTHAA

Sequences:

>Translated_783_residues
MASTDAYGAPAGTHCESGRKKRKGRLSGHVSLLAGPAYSKFIVIEPILRRLVPTLIIIFLIILGVARVFSLLAWRDDIEL
QHKAALSGATAHLAQMIERVANGIETGAQLSAKDLQDAMTELRSRGLTSSGMTIAIVDAQSMIKAASGPAGIAGSQIDTI
LGDAQPLFLFAERAGVLRVVLQGEAAFGALAKPMTAPYSIIAVEPESTIFAEWKRAVSLNVTLFAGTIGVMFAILYAYFS
QAARAREADDLSGQIQRRIDMALARGRCGLWDWDMARGRIYWSRSMYEMLGYEAQDAVLPFGDVAAIINEEDGDLYSIAE
QAAAGDISHVDRVFRMRHADGSWVWMRVRAEIASEGDLHLVGIAFDVSEQHRFAQQTAEADMRIREAIENISEAFVLWDA
NNRLVMANSKFSEYAGLPVWTLKPGVPRNEVDAHTRPFTFERRMANEHNRAGGQTFERQLSDGRWLQVNERRTQDGGMVS
IGTDITQLKLHQERLVDSERRLMATVHDLSIARKGERDRVRELSELARKYSLEKERAEAANRAKSEFLANMSHELRTPLN
AIIGFSEMIQAGTFGPLGSDRYEEYINDIHTSGNFLLNVINDILDMSKIEAGHFSLDREEIDLCPLINETVRIISLQAEE
KNIAVETRIEDAMELYADRRAIKQVLINLLSNAVKFTSYGGRITVRARKTGAALFMTIQDTGVGIPKSALRKIGQPFEQV
ENQFTKTHTGSGLGLAISRSLAELHGGWLRIRSTERVGTVVSVCIPDRNPAPNAGHDARTHAA
>Mature_782_residues
ASTDAYGAPAGTHCESGRKKRKGRLSGHVSLLAGPAYSKFIVIEPILRRLVPTLIIIFLIILGVARVFSLLAWRDDIELQ
HKAALSGATAHLAQMIERVANGIETGAQLSAKDLQDAMTELRSRGLTSSGMTIAIVDAQSMIKAASGPAGIAGSQIDTIL
GDAQPLFLFAERAGVLRVVLQGEAAFGALAKPMTAPYSIIAVEPESTIFAEWKRAVSLNVTLFAGTIGVMFAILYAYFSQ
AARAREADDLSGQIQRRIDMALARGRCGLWDWDMARGRIYWSRSMYEMLGYEAQDAVLPFGDVAAIINEEDGDLYSIAEQ
AAAGDISHVDRVFRMRHADGSWVWMRVRAEIASEGDLHLVGIAFDVSEQHRFAQQTAEADMRIREAIENISEAFVLWDAN
NRLVMANSKFSEYAGLPVWTLKPGVPRNEVDAHTRPFTFERRMANEHNRAGGQTFERQLSDGRWLQVNERRTQDGGMVSI
GTDITQLKLHQERLVDSERRLMATVHDLSIARKGERDRVRELSELARKYSLEKERAEAANRAKSEFLANMSHELRTPLNA
IIGFSEMIQAGTFGPLGSDRYEEYINDIHTSGNFLLNVINDILDMSKIEAGHFSLDREEIDLCPLINETVRIISLQAEEK
NIAVETRIEDAMELYADRRAIKQVLINLLSNAVKFTSYGGRITVRARKTGAALFMTIQDTGVGIPKSALRKIGQPFEQVE
NQFTKTHTGSGLGLAISRSLAELHGGWLRIRSTERVGTVVSVCIPDRNPAPNAGHDARTHAA

Specific function: Member of the two-component regulatory system involved in the regulation of polar organelle development. PleC functions as a membrane-associated protein kinase that transfers phosphate to the response regulator pleD, leading to its activation [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=296, Percent_Identity=37.5, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1789149, Length=259, Percent_Identity=34.3629343629344, Blast_Score=146, Evalue=6e-36,
Organism=Escherichia coli, GI48994928, Length=232, Percent_Identity=36.2068965517241, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=34.3873517786561, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI145693157, Length=232, Percent_Identity=36.6379310344828, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788393, Length=276, Percent_Identity=25.7246376811594, Blast_Score=107, Evalue=4e-24,
Organism=Escherichia coli, GI1786600, Length=235, Percent_Identity=29.7872340425532, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788549, Length=254, Percent_Identity=27.5590551181102, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1790436, Length=266, Percent_Identity=27.8195488721804, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI87082128, Length=218, Percent_Identity=29.8165137614679, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1786912, Length=281, Percent_Identity=28.1138790035587, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1786783, Length=250, Percent_Identity=24.8, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790861, Length=247, Percent_Identity=25.9109311740891, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1790346, Length=225, Percent_Identity=24.8888888888889, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788279, Length=231, Percent_Identity=24.6753246753247, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789403, Length=253, Percent_Identity=28.0632411067194, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 86513; Mature: 86382

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTDAYGAPAGTHCESGRKKRKGRLSGHVSLLAGPAYSKFIVIEPILRRLVPTLIIIFL
CCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHH
IILGVARVFSLLAWRDDIELQHKAALSGATAHLAQMIERVANGIETGAQLSAKDLQDAMT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ELRSRGLTSSGMTIAIVDAQSMIKAASGPAGIAGSQIDTILGDAQPLFLFAERAGVLRVV
HHHHCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEEHHCCCEEEEE
LQGEAAFGALAKPMTAPYSIIAVEPESTIFAEWKRAVSLNVTLFAGTIGVMFAILYAYFS
EECCHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHH
QAARAREADDLSGQIQRRIDMALARGRCGLWDWDMARGRIYWSRSMYEMLGYEAQDAVLP
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEHHHHHHHHCCCCCCCCCC
FGDVAAIINEEDGDLYSIAEQAAAGDISHVDRVFRMRHADGSWVWMRVRAEIASEGDLHL
CCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEHHCCCCCEEE
VGIAFDVSEQHRFAQQTAEADMRIREAIENISEAFVLWDANNRLVMANSKFSEYAGLPVW
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHCCCEEE
TLKPGVPRNEVDAHTRPFTFERRMANEHNRAGGQTFERQLSDGRWLQVNERRTQDGGMVS
EECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCCCCCCCEEE
IGTDITQLKLHQERLVDSERRLMATVHDLSIARKGERDRVRELSELARKYSLEKERAEAA
ECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHH
NRAKSEFLANMSHELRTPLNAIIGFSEMIQAGTFGPLGSDRYEEYINDIHTSGNFLLNVI
HHHHHHHHHHHHHHHHCHHHHHHCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
NDILDMSKIEAGHFSLDREEIDLCPLINETVRIISLQAEEKNIAVETRIEDAMELYADRR
HHHHHHHHCCCCCCCCCHHHCCHHHHHHHHEEEEEEEECCCCCEEHHHHHHHHHHHHHHH
AIKQVLINLLSNAVKFTSYGGRITVRARKTGAALFMTIQDTGVGIPKSALRKIGQPFEQV
HHHHHHHHHHHHHHHEECCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHCCHHHHH
ENQFTKTHTGSGLGLAISRSLAELHGGWLRIRSTERVGTVVSVCIPDRNPAPNAGHDART
HHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHCCEEEEEECCCCCCCCCCCCCCC
HAA
CCC
>Mature Secondary Structure 
ASTDAYGAPAGTHCESGRKKRKGRLSGHVSLLAGPAYSKFIVIEPILRRLVPTLIIIFL
CCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEECCCCCCEEEHHHHHHHHHHHHHHHHH
IILGVARVFSLLAWRDDIELQHKAALSGATAHLAQMIERVANGIETGAQLSAKDLQDAMT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
ELRSRGLTSSGMTIAIVDAQSMIKAASGPAGIAGSQIDTILGDAQPLFLFAERAGVLRVV
HHHHCCCCCCCCEEEEECHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEEHHCCCEEEEE
LQGEAAFGALAKPMTAPYSIIAVEPESTIFAEWKRAVSLNVTLFAGTIGVMFAILYAYFS
EECCHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHH
QAARAREADDLSGQIQRRIDMALARGRCGLWDWDMARGRIYWSRSMYEMLGYEAQDAVLP
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCEEEEHHHHHHHHCCCCCCCCCC
FGDVAAIINEEDGDLYSIAEQAAAGDISHVDRVFRMRHADGSWVWMRVRAEIASEGDLHL
CCCEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEHHCCCCCEEE
VGIAFDVSEQHRFAQQTAEADMRIREAIENISEAFVLWDANNRLVMANSKFSEYAGLPVW
EEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEEEEECCCHHHHCCCEEE
TLKPGVPRNEVDAHTRPFTFERRMANEHNRAGGQTFERQLSDGRWLQVNERRTQDGGMVS
EECCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHCCCCEEEECCCCCCCCCEEE
IGTDITQLKLHQERLVDSERRLMATVHDLSIARKGERDRVRELSELARKYSLEKERAEAA
ECCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHH
NRAKSEFLANMSHELRTPLNAIIGFSEMIQAGTFGPLGSDRYEEYINDIHTSGNFLLNVI
HHHHHHHHHHHHHHHHCHHHHHHCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHH
NDILDMSKIEAGHFSLDREEIDLCPLINETVRIISLQAEEKNIAVETRIEDAMELYADRR
HHHHHHHHCCCCCCCCCHHHCCHHHHHHHHEEEEEEEECCCCCEEHHHHHHHHHHHHHHH
AIKQVLINLLSNAVKFTSYGGRITVRARKTGAALFMTIQDTGVGIPKSALRKIGQPFEQV
HHHHHHHHHHHHHHHEECCCCEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHCCHHHHH
ENQFTKTHTGSGLGLAISRSLAELHGGWLRIRSTERVGTVVSVCIPDRNPAPNAGHDART
HHHHHHCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHCCEEEEEECCCCCCCCCCCCCCC
HAA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]