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The map label for this gene is pip [H]

Identifier: 225851860

GI number: 225851860

Start: 346220

End: 347170

Strand: Reverse

Name: pip [H]

Synonym: BMEA_A0352

Alternate gene names: 225851860

Gene position: 347170-346220 (Counterclockwise)

Preceding gene: 225851862

Following gene: 225851858

Centisome position: 16.33

GC content: 58.99

Gene sequence:

>951_bases
ATGACGCGCAATACGCTTTATCCCGAAATTGAGCCCTTCAAGGAAGAAATGTTGCAGGTATCCTCCCTGCACCGCATTCA
TGTCGAGCAATGCGGCAATCCTGACGGCAAACCCGTCATCATGATCCATGGCGGGCCCGGCGGCGGCATAACGCCCACCA
TGCGCCGCCTGCACGACCCGAAACGCTATCGTATCATCCTGTTCGACCAGCGCGGCTGCGGCCGCTCCACGCCCCATGCG
GAACTGCGCGAAAATACCACATGGGATCTCGTCGCCGACATGGAGCATATCCGCGCCCATCTGGGCATCGACAAATGGCA
GGTCTTCGGCGGTTCATGGGGGTCCACACTGGGTCTTGCCTATGCCGAAACCCATCCCGAGCGCGTATCGGAACTGGTGC
TGCGCGGCATTTTCATGGTGCGCCGCTTCGAGGTCGACTGGATGTATTCCAACGGCGCGAGCATCATCTTCCCCGATCAT
TTCGAGGCCTATCAGGAGCATATTCCCGAAGCTGAACGCGGCGATATGATCGCGGCCTATTACAAGCGCCTGACCGACCG
CGACCCGCGGGTACAGCTTGAGGCCGCACGCCGATGGGCACGCTGGGAAGGCTCCGTGATCTCGCTTCTGCCTGATCCGG
CCCGCGTCGATGCTTTCGGCGAGGATCAGTATGCAATCGCCTTCGCACGCATCGAGTGCCATTATTTCCAGAACCGCGGC
TTCCTCGAAAGCGACGACCAGTTGCTGCGCAATGTCGAGCGCATCCGCCATATTCCGGGTGTCATCGTCCATGGGCGCTA
CGATATCTGCACACCCTTCATCAATGCCTGGCAGTTGAAGAAGATGTGGCCGGAAGCCGACCTTAAAATCGTGGAAGACA
GCGGCCATGCCGTGACCGAACCCGGCATCATGCATGAGCTGATCGAAGCGACCAAACGTTTCTGCGAATAA

Upstream 100 bases:

>100_bases
CCCCTGCCGCCATCTGGCCTTATTGTGTGGTAGGTTGACGCATCACCGAAACGCAACCGGCGGGCCTATCCTGCCAGCGG
AAGGGAACAAAAGGCATTTC

Downstream 100 bases:

>100_bases
GCTGGAGCATTTCCAGCAAAAGCGCGAAGCGTGTCGTACTCTTACGACACGCTTTAAAGGCGCCGGATCGGCGCCTTTTT
CTTATCGGATTCAGGTCCGC

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MTRNTLYPEIEPFKEEMLQVSSLHRIHVEQCGNPDGKPVIMIHGGPGGGITPTMRRLHDPKRYRIILFDQRGCGRSTPHA
ELRENTTWDLVADMEHIRAHLGIDKWQVFGGSWGSTLGLAYAETHPERVSELVLRGIFMVRRFEVDWMYSNGASIIFPDH
FEAYQEHIPEAERGDMIAAYYKRLTDRDPRVQLEAARRWARWEGSVISLLPDPARVDAFGEDQYAIAFARIECHYFQNRG
FLESDDQLLRNVERIRHIPGVIVHGRYDICTPFINAWQLKKMWPEADLKIVEDSGHAVTEPGIMHELIEATKRFCE

Sequences:

>Translated_316_residues
MTRNTLYPEIEPFKEEMLQVSSLHRIHVEQCGNPDGKPVIMIHGGPGGGITPTMRRLHDPKRYRIILFDQRGCGRSTPHA
ELRENTTWDLVADMEHIRAHLGIDKWQVFGGSWGSTLGLAYAETHPERVSELVLRGIFMVRRFEVDWMYSNGASIIFPDH
FEAYQEHIPEAERGDMIAAYYKRLTDRDPRVQLEAARRWARWEGSVISLLPDPARVDAFGEDQYAIAFARIECHYFQNRG
FLESDDQLLRNVERIRHIPGVIVHGRYDICTPFINAWQLKKMWPEADLKIVEDSGHAVTEPGIMHELIEATKRFCE
>Mature_315_residues
TRNTLYPEIEPFKEEMLQVSSLHRIHVEQCGNPDGKPVIMIHGGPGGGITPTMRRLHDPKRYRIILFDQRGCGRSTPHAE
LRENTTWDLVADMEHIRAHLGIDKWQVFGGSWGSTLGLAYAETHPERVSELVLRGIFMVRRFEVDWMYSNGASIIFPDHF
EAYQEHIPEAERGDMIAAYYKRLTDRDPRVQLEAARRWARWEGSVISLLPDPARVDAFGEDQYAIAFARIECHYFQNRGF
LESDDQLLRNVERIRHIPGVIVHGRYDICTPFINAWQLKKMWPEADLKIVEDSGHAVTEPGIMHELIEATKRFCE

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36547; Mature: 36416

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRNTLYPEIEPFKEEMLQVSSLHRIHVEQCGNPDGKPVIMIHGGPGGGITPTMRRLHDP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHCCC
KRYRIILFDQRGCGRSTPHAELRENTTWDLVADMEHIRAHLGIDKWQVFGGSWGSTLGLA
CEEEEEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHEEE
YAETHPERVSELVLRGIFMVRRFEVDWMYSNGASIIFPDHFEAYQEHIPEAERGDMIAAY
HHHCCHHHHHHHHHHHHHHHHHEEEEEEEECCCEEEECHHHHHHHHHCCCCCCCCCHHHH
YKRLTDRDPRVQLEAARRWARWEGSVISLLPDPARVDAFGEDQYAIAFARIECHYFQNRG
HHHHCCCCCCEEHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCEEEEEEEEEEEEECCCC
FLESDDQLLRNVERIRHIPGVIVHGRYDICTPFINAWQLKKMWPEADLKIVEDSGHAVTE
CCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECC
PGIMHELIEATKRFCE
CHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRNTLYPEIEPFKEEMLQVSSLHRIHVEQCGNPDGKPVIMIHGGPGGGITPTMRRLHDP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHCCC
KRYRIILFDQRGCGRSTPHAELRENTTWDLVADMEHIRAHLGIDKWQVFGGSWGSTLGLA
CEEEEEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHEEE
YAETHPERVSELVLRGIFMVRRFEVDWMYSNGASIIFPDHFEAYQEHIPEAERGDMIAAY
HHHCCHHHHHHHHHHHHHHHHHEEEEEEEECCCEEEECHHHHHHHHHCCCCCCCCCHHHH
YKRLTDRDPRVQLEAARRWARWEGSVISLLPDPARVDAFGEDQYAIAFARIECHYFQNRG
HHHHCCCCCCEEHHHHHHHHHCCCCEEEECCCCHHCCCCCCCCEEEEEEEEEEEEECCCC
FLESDDQLLRNVERIRHIPGVIVHGRYDICTPFINAWQLKKMWPEADLKIVEDSGHAVTE
CCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEECC
PGIMHELIEATKRFCE
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA