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The map label for this gene is kdgR [H]

Identifier: 225851761

GI number: 225851761

Start: 246281

End: 247075

Strand: Reverse

Name: kdgR [H]

Synonym: BMEA_A0242

Alternate gene names: 225851761

Gene position: 247075-246281 (Counterclockwise)

Preceding gene: 225851773

Following gene: 225851760

Centisome position: 11.62

GC content: 60.75

Gene sequence:

>795_bases
ATGCGGGAGCCGACCTTGGAAACTGACGATCGCTATCGCGCGCCCGCGCTGGACAAGGGGCTGGACATATTGGAATTGCT
GGCGAGTGTGGATGGCGGGCTGACGCAGGCCGAGATCGCCAAGCATCTCGACCGCAGCCCCAACGAATTTTACCGGATGC
TGGACCGGCTGGTGAAGCGCGGCTATGTCACCAAACTCGATGGCGACCGTTATTCACTGACGCTGAAGCTGTTCGGGCTT
GCGCAACTCCATGCGCCGGTGCGCAGGCTTGCCTCCTTCGCCACGCCCTTCATGCGCGAGCTTGCCGACCGTTCCAAACA
GGCCAATCAGCTTGCCGTGTTCGACCGCGGCTCGGTGGTGGTCATCGCTCAGCAGGAAGCACCGGATTACTGGGGCATTT
CCATCCGCGTCGGCTCGCATATCAGCCTGTTCGATACCGGCTCCGGTCACGTTCTGCTCGCCTTCCGCTCACCGGAAGAG
CGCGAAATGATGATTGCCGCCCATGTGAAAAGCCGTGATGAAGTCAATCTGGATCAGGACTTCTATGACCGTCTCGACCA
GATACGCGAGCGCGGATACGAGATGATGGCGAGCGCACAGATGGCGGGCGCCTATAATCTTTCCGCGCCGATCCTCGGCC
CGGACGGCACCTGCGTTGCAGCCCTCACCTGCCCCTATATCACGCTCGTCAATCCGTCTTCGGCCCCTGATATCACCCAG
ACGATCAGCCTGTTGCAGAAGACGGTACGCGACCTCTCCAAGCTGGTGGGCGCGGATGTAGGCGTGACAGGATAA

Upstream 100 bases:

>100_bases
CCATTTATATGCAAACATATTATTCAAACATGGTCAAGGCGATTTGCGGGTGGTTATTCCTTTCACCCTTTACGCTGTTC
GTATATGAAGAAAGCCATTT

Downstream 100 bases:

>100_bases
ATTCTGATTTGAAAAATATCTTCTTTTTTGAAAGCATCGAAAGCAAGGAGGATTCCCATGCTGATCGATACGCACCTGCA
CCTGATCGACAAAAACGCGC

Product: HTH-type transcriptional repressor AllR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKRGYVTKLDGDRYSLTLKLFGL
AQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVVVIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEE
REMMIAAHVKSRDEVNLDQDFYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCVAALTCPYITLVNPSSAPDITQ
TISLLQKTVRDLSKLVGADVGVTG

Sequences:

>Translated_264_residues
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKRGYVTKLDGDRYSLTLKLFGL
AQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVVVIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEE
REMMIAAHVKSRDEVNLDQDFYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCVAALTCPYITLVNPSSAPDITQ
TISLLQKTVRDLSKLVGADVGVTG
>Mature_264_residues
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKRGYVTKLDGDRYSLTLKLFGL
AQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVVVIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEE
REMMIAAHVKSRDEVNLDQDFYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCVAALTCPYITLVNPSSAPDITQ
TISLLQKTVRDLSKLVGADVGVTG

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=225, Percent_Identity=27.5555555555556, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788581, Length=214, Percent_Identity=22.8971962616822, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1786715, Length=253, Percent_Identity=26.4822134387352, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 29203; Mature: 29203

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKR
CCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHC
GYVTKLDGDRYSLTLKLFGLAQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVV
CCEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEE
VIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEEREMMIAAHVKSRDEVNLDQD
EEEECCCCCEEEEEEEECCEEEEEECCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCHH
FYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCVAALTCPYITLVNPSSAPDITQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCHHHH
TISLLQKTVRDLSKLVGADVGVTG
HHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MREPTLETDDRYRAPALDKGLDILELLASVDGGLTQAEIAKHLDRSPNEFYRMLDRLVKR
CCCCCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHC
GYVTKLDGDRYSLTLKLFGLAQLHAPVRRLASFATPFMRELADRSKQANQLAVFDRGSVV
CCEEEECCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEE
VIAQQEAPDYWGISIRVGSHISLFDTGSGHVLLAFRSPEEREMMIAAHVKSRDEVNLDQD
EEEECCCCCEEEEEEEECCEEEEEECCCCEEEEEECCCCHHHEEEEEECCCCCCCCCCHH
FYDRLDQIRERGYEMMASAQMAGAYNLSAPILGPDGTCVAALTCPYITLVNPSSAPDITQ
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCCHHHH
TISLLQKTVRDLSKLVGADVGVTG
HHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]