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The map label for this gene is gap [H]

Identifier: 225630090

GI number: 225630090

Start: 280564

End: 281550

Strand: Direct

Name: gap [H]

Synonym: WRi_002690

Alternate gene names: 225630090

Gene position: 280564-281550 (Clockwise)

Preceding gene: 225630088

Following gene: 225630091

Centisome position: 19.4

GC content: 37.69

Gene sequence:

>987_bases
ATGACGGTTCGCGTAGGAATTAATGGTCTGGGTAGAATAGGCAGAGGCGTATTGCGTGCTATTTTCGAAATAGAAGAATA
TAGCAAACAAATAGAAGTTGTAGCTGTCAATGGATCGCTCAGTGCAAAGCAGCATGCACATTTGATTAAATATGATTCTG
TTCATGGCAAATTCAGTGGTGATATTGATTTTAATGAGTCTCAAAATTGGATTTCTATAAATGGCAAAAAGTTTTCTTTA
TATAGAGAACGGAATCCTGAAAATATTCCTTGGAATGTTGATGTAATACTTGAATGTACTGGTGCATTCAATAAACGTGA
AGAAGCAATAAGGCACAATGCAGAGAAAGTAATTGTCTCTGCTCCAGTTCCGGATGCTGATGTCACTATAGTTTATGGTG
TGAATGACGATATGCTCGAAAAAGAGCATAAAGTGATATCAGCAGGTTCTTGCACTACAAATTGCCTTGCTCCGATTGTG
AAAGTCCTACATTCTAGTTTAAGCATAAAAAGCGGTTTTATGACTACTATACATGCCTACACGAATGATCAAAATGTTCT
TGATGGTAATCATAAAGATTTGCGTAGAGCAAGGGCTTGCGGATTATCTATGGTGCCAACTACAACCGGGGCAGCAAAAA
CAATTGGTTCTATAATTCCTGAATTAAAGGGAAAGCTAGATGGCACTGCCGTCAGAGTTCCGGTTAGCAATGTTTCTATG
GTTGATTTTAAATTTACAACTGATAAGAAAGCGACCGTTAAAGAAATCAATGAAATGTTTAAGGATGCAGCAAGCAATGT
GCTTTCTGTATGTGCGGAACCTTTAGTCTCAATAGATTTTGTGCATAACCCTTATAGTGCAATTGTGGATTTAACTGGTA
CATATGTTACAGGTGATATATGCAGGGTTGCAGCGTGGTATGACAATGAGTGGGCTTTTTCGCTGAGAATGTTAGACATA
GCATTATTGAGCTATAGTAAAGTATGA

Upstream 100 bases:

>100_bases
AATATTAATATATTAAGGTTAAAACTGCCAATTAGCAGTCAAAAGAATAAAATGAAATATCAAGTGATATCCTCTATAAT
TAAATTTTTTGAATGAAGAG

Downstream 100 bases:

>100_bases
ACTGGAACTCAAACAAATACGCCTCATTTTATGAGCACTTTGCGGAACTCAGAAAAAGAGTTATCTTTTGCTTTCTATTT
TTTTGCGTTGCTTTTGGTTT

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTVRVGINGLGRIGRGVLRAIFEIEEYSKQIEVVAVNGSLSAKQHAHLIKYDSVHGKFSGDIDFNESQNWISINGKKFSL
YRERNPENIPWNVDVILECTGAFNKREEAIRHNAEKVIVSAPVPDADVTIVYGVNDDMLEKEHKVISAGSCTTNCLAPIV
KVLHSSLSIKSGFMTTIHAYTNDQNVLDGNHKDLRRARACGLSMVPTTTGAAKTIGSIIPELKGKLDGTAVRVPVSNVSM
VDFKFTTDKKATVKEINEMFKDAASNVLSVCAEPLVSIDFVHNPYSAIVDLTGTYVTGDICRVAAWYDNEWAFSLRMLDI
ALLSYSKV

Sequences:

>Translated_328_residues
MTVRVGINGLGRIGRGVLRAIFEIEEYSKQIEVVAVNGSLSAKQHAHLIKYDSVHGKFSGDIDFNESQNWISINGKKFSL
YRERNPENIPWNVDVILECTGAFNKREEAIRHNAEKVIVSAPVPDADVTIVYGVNDDMLEKEHKVISAGSCTTNCLAPIV
KVLHSSLSIKSGFMTTIHAYTNDQNVLDGNHKDLRRARACGLSMVPTTTGAAKTIGSIIPELKGKLDGTAVRVPVSNVSM
VDFKFTTDKKATVKEINEMFKDAASNVLSVCAEPLVSIDFVHNPYSAIVDLTGTYVTGDICRVAAWYDNEWAFSLRMLDI
ALLSYSKV
>Mature_327_residues
TVRVGINGLGRIGRGVLRAIFEIEEYSKQIEVVAVNGSLSAKQHAHLIKYDSVHGKFSGDIDFNESQNWISINGKKFSLY
RERNPENIPWNVDVILECTGAFNKREEAIRHNAEKVIVSAPVPDADVTIVYGVNDDMLEKEHKVISAGSCTTNCLAPIVK
VLHSSLSIKSGFMTTIHAYTNDQNVLDGNHKDLRRARACGLSMVPTTTGAAKTIGSIIPELKGKLDGTAVRVPVSNVSMV
DFKFTTDKKATVKEINEMFKDAASNVLSVCAEPLVSIDFVHNPYSAIVDLTGTYVTGDICRVAAWYDNEWAFSLRMLDIA
LLSYSKV

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=337, Percent_Identity=37.9821958456973, Blast_Score=224, Evalue=9e-59,
Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=38.1656804733728, Blast_Score=222, Evalue=4e-58,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=41.6167664670659, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1788079, Length=332, Percent_Identity=40.0602409638554, Blast_Score=237, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=334, Percent_Identity=40.1197604790419, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17534677, Length=333, Percent_Identity=39.3393393393393, Blast_Score=224, Evalue=5e-59,
Organism=Caenorhabditis elegans, GI32566163, Length=338, Percent_Identity=39.9408284023669, Blast_Score=217, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI17568413, Length=338, Percent_Identity=39.9408284023669, Blast_Score=217, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6321631, Length=331, Percent_Identity=39.5770392749245, Blast_Score=247, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6322468, Length=331, Percent_Identity=38.9728096676737, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6322409, Length=331, Percent_Identity=39.2749244712991, Blast_Score=244, Evalue=2e-65,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=39.4658753709199, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=39.4658753709199, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=39.1691394658754, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=39.1691394658754, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI19922412, Length=333, Percent_Identity=38.1381381381381, Blast_Score=216, Evalue=2e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36054; Mature: 35922

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVGINGLGRIGRGVLRAIFEIEEYSKQIEVVAVNGSLSAKQHAHLIKYDSVHGKFSG
CEEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHEEEEECCCCCEECC
DIDFNESQNWISINGKKFSLYRERNPENIPWNVDVILECTGAFNKREEAIRHNAEKVIVS
CCCCCCCCCEEEECCEEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEEEE
APVPDADVTIVYGVNDDMLEKEHKVISAGSCTTNCLAPIVKVLHSSLSIKSGFMTTIHAY
CCCCCCCEEEEEECCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
TNDQNVLDGNHKDLRRARACGLSMVPTTTGAAKTIGSIIPELKGKLDGTAVRVPVSNVSM
CCCCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCEE
VDFKFTTDKKATVKEINEMFKDAASNVLSVCAEPLVSIDFVHNPYSAIVDLTGTYVTGDI
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHEECCCCEEECCC
CRVAAWYDNEWAFSLRMLDIALLSYSKV
EEEEEEECCCEEEEHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVRVGINGLGRIGRGVLRAIFEIEEYSKQIEVVAVNGSLSAKQHAHLIKYDSVHGKFSG
EEEEECCCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCHHHEEEEECCCCCEECC
DIDFNESQNWISINGKKFSLYRERNPENIPWNVDVILECTGAFNKREEAIRHNAEKVIVS
CCCCCCCCCEEEECCEEEEEEECCCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCEEEEE
APVPDADVTIVYGVNDDMLEKEHKVISAGSCTTNCLAPIVKVLHSSLSIKSGFMTTIHAY
CCCCCCCEEEEEECCHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEE
TNDQNVLDGNHKDLRRARACGLSMVPTTTGAAKTIGSIIPELKGKLDGTAVRVPVSNVSM
CCCCCCCCCCHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCEE
VDFKFTTDKKATVKEINEMFKDAASNVLSVCAEPLVSIDFVHNPYSAIVDLTGTYVTGDI
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHEECCCCEEECCC
CRVAAWYDNEWAFSLRMLDIALLSYSKV
EEEEEEECCCEEEEHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8045900; 10984043 [H]