Click here to switch to the map view.

The map label for this gene is phoP [H]

Identifier: 222527314

GI number: 222527314

Start: 5076028

End: 5076426

Strand: Direct

Name: phoP [H]

Synonym: Chy400_4099

Alternate gene names: 222527314

Gene position: 5076028-5076426 (Clockwise)

Preceding gene: 222527313

Following gene: 222527315

Centisome position: 96.34

GC content: 52.88

Gene sequence:

>399_bases
GTGACATCACTACAGAAAATCCTCTTCATCGAGGATGATCCCGATATTCAGATGGTAGCCCAACTGGCGCTTGAGGCGGT
TGGTGGCTATGCAGTGCAAATCTGTAGTTCAGGTGCAGAAGCACTCGCCACCGCCGAGCAGTTTGCCCCCGATCTGATTT
TGCTCGATGTGATGATGCCGGGAATGGACGGGCCAACCACGCTGAAAGAGCTACGGAAACGCCCTGCACTGGCTAACACG
CCGGTTATCTTCATGACGGCCCGCGTCCAGCGCCACGAAGTCGAACAGTATCTGGCACTAGGGGCAGTTGATGTTATCTC
CAAACCCTTTGATCCAATGACCTTATCAGAACAAGTTGCAGCAATCTGGTTGAAAGCTAATGAAACCCGATCCCGCTGA

Upstream 100 bases:

>100_bases
ACCAACACCGAGTTGTTAACAACGGTCAGTCGTTTGCTTGATCAGCCAATTTCGTCACCGGTTACCCCAAATGAAGCTCG
TTAGGAAAGGAGCTAACGTT

Downstream 100 bases:

>100_bases
ACAGTTTGAAGCACTGCGCAAACGGTATGCCGCGCAAATTGGTGAACGTGTGGCGGCTATTCATGCTGCCTGGAACCAGC
TTGTCCAGAGCGACTGGGAT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 132; Mature: 131

Protein sequence:

>132_residues
MTSLQKILFIEDDPDIQMVAQLALEAVGGYAVQICSSGAEALATAEQFAPDLILLDVMMPGMDGPTTLKELRKRPALANT
PVIFMTARVQRHEVEQYLALGAVDVISKPFDPMTLSEQVAAIWLKANETRSR

Sequences:

>Translated_132_residues
MTSLQKILFIEDDPDIQMVAQLALEAVGGYAVQICSSGAEALATAEQFAPDLILLDVMMPGMDGPTTLKELRKRPALANT
PVIFMTARVQRHEVEQYLALGAVDVISKPFDPMTLSEQVAAIWLKANETRSR
>Mature_131_residues
TSLQKILFIEDDPDIQMVAQLALEAVGGYAVQICSSGAEALATAEQFAPDLILLDVMMPGMDGPTTLKELRKRPALANTP
VIFMTARVQRHEVEQYLALGAVDVISKPFDPMTLSEQVAAIWLKANETRSR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=127, Percent_Identity=34.6456692913386, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1788550, Length=111, Percent_Identity=35.1351351351351, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=33.0508474576271, Blast_Score=64, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=106, Percent_Identity=32.0754716981132, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1790299, Length=105, Percent_Identity=36.1904761904762, Blast_Score=62, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=105, Percent_Identity=34.2857142857143, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 14445; Mature: 14314

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSLQKILFIEDDPDIQMVAQLALEAVGGYAVQICSSGAEALATAEQFAPDLILLDVMMP
CCCCCEEEEEECCCCHHHHHHHHHHHHCCHHEEHHHCCHHHHHHHHHHCCHHEEEEHHCC
GMDGPTTLKELRKRPALANTPVIFMTARVQRHEVEQYLALGAVDVISKPFDPMTLSEQVA
CCCCCHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AIWLKANETRSR
HHEEECCCCCCC
>Mature Secondary Structure 
TSLQKILFIEDDPDIQMVAQLALEAVGGYAVQICSSGAEALATAEQFAPDLILLDVMMP
CCCCEEEEEECCCCHHHHHHHHHHHHCCHHEEHHHCCHHHHHHHHHHCCHHEEEEHHCC
GMDGPTTLKELRKRPALANTPVIFMTARVQRHEVEQYLALGAVDVISKPFDPMTLSEQVA
CCCCCHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
AIWLKANETRSR
HHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]