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The map label for this gene is add [H]

Identifier: 222526824

GI number: 222526824

Start: 4479602

End: 4480642

Strand: Reverse

Name: add [H]

Synonym: Chy400_3599

Alternate gene names: 222526824

Gene position: 4480642-4479602 (Counterclockwise)

Preceding gene: 222526825

Following gene: 222526823

Centisome position: 85.04

GC content: 59.27

Gene sequence:

>1041_bases
ATGACCCTGCAAGCACAAGCTGACACAGCTCCCATAGCCCGTGATGTGCCATTGATCGACTTGCATCGCCATCTCGATGG
CAATGTGCGGCTCACCACTATCCTCGACGTTGCCCGCACGTATGGTATTCGCCTGCCTGCCGACACCGTCGAAGGATTAC
GCCCATACGCGCAGATTCAGGGTGTGGCAGCTTCAGTAATGGATTTCATCGCGCGTTTCGATCTTCTGAAGCTGATCTGC
GTTGATGAAGATGTAGTGGCGCGCATTGCCGAAGAGAATGTCGAAGATGCAGCCAATGAAGGAATCGACTACATCGAGTT
ACGCTGCTCACCGGCATTCATGGGCGAACGCTACGGTCTCGATCCGACCCGCGTGCTGGCGGCGGTTTGCCGGGGTGTGC
GTGCCGGCATGGCCCGCTACCCGGTTCAGGCACAGATCATCGGGATTATGTCACGTCACATGGGTGAAGAGAGCTGCTGG
CGCGAATTGGAAGCAGCCATCGCGCTGATGAGTGAAGGTGTAGTCGGGATCGATCTCGCCGGCGATGAAGCCAATTTTCC
CGGTACCCGGTTTGTGAAGCACTTTGCCCGTGCTCGCGCCGCCGGTCTGCGCATCACGGTGCATGCCGGTGAAGCCGCCG
GCGCGTGGAGTGTCCGGCAAGCGATTGAGGAACTGGGTGCTGAACGTATCGGCCACGGCGTGCGGGCTGTCGAAGACCCG
GCTGTTTTGCAACTGATCGCCGAACGTGGGGTTGCCCTGGAGGTATGCCCGACCAGTAACGTGCAAACCCAGACGGTCAG
CGGCTACGAGAGCCACCCGCTACCACAACTATTGCGCCGTGGCCTGCTGGTCACGCTCAACACCGATGACCCCGGCATTA
GCGCCATCGATCTGCCACACGAATATCGCATTGCCCGCGACCGGCTTGGTCTCACTACCGAAGAACTACGGACATTGCAG
GCTCATGCCCTGTCCGCTGCCTTTATCGATGAAGCCACCCGCGCTGCTTTGCTGCACAAAGCACGTTCACGCACCACTTG
A

Upstream 100 bases:

>100_bases
GCTACGCTGATCGCCCGCTTGTCGTCCGTGGCCCCGGCGCCGGCGTAGAAGTGACCGCAGCCGGTGTGTTGAGCGATATT
ATTGCCACCGCACGAGAGTT

Downstream 100 bases:

>100_bases
GTTTTATAACGCGGCGTGTTACACTATTGACGCAAAGCAGCAATGTAATCACTCCCCACCAGATGAAGGAGTCTGGCAAT
GACGCACGAACACTCCCCGA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTLQAQADTAPIARDVPLIDLHRHLDGNVRLTTILDVARTYGIRLPADTVEGLRPYAQIQGVAASVMDFIARFDLLKLIC
VDEDVVARIAEENVEDAANEGIDYIELRCSPAFMGERYGLDPTRVLAAVCRGVRAGMARYPVQAQIIGIMSRHMGEESCW
RELEAAIALMSEGVVGIDLAGDEANFPGTRFVKHFARARAAGLRITVHAGEAAGAWSVRQAIEELGAERIGHGVRAVEDP
AVLQLIAERGVALEVCPTSNVQTQTVSGYESHPLPQLLRRGLLVTLNTDDPGISAIDLPHEYRIARDRLGLTTEELRTLQ
AHALSAAFIDEATRAALLHKARSRTT

Sequences:

>Translated_346_residues
MTLQAQADTAPIARDVPLIDLHRHLDGNVRLTTILDVARTYGIRLPADTVEGLRPYAQIQGVAASVMDFIARFDLLKLIC
VDEDVVARIAEENVEDAANEGIDYIELRCSPAFMGERYGLDPTRVLAAVCRGVRAGMARYPVQAQIIGIMSRHMGEESCW
RELEAAIALMSEGVVGIDLAGDEANFPGTRFVKHFARARAAGLRITVHAGEAAGAWSVRQAIEELGAERIGHGVRAVEDP
AVLQLIAERGVALEVCPTSNVQTQTVSGYESHPLPQLLRRGLLVTLNTDDPGISAIDLPHEYRIARDRLGLTTEELRTLQ
AHALSAAFIDEATRAALLHKARSRTT
>Mature_345_residues
TLQAQADTAPIARDVPLIDLHRHLDGNVRLTTILDVARTYGIRLPADTVEGLRPYAQIQGVAASVMDFIARFDLLKLICV
DEDVVARIAEENVEDAANEGIDYIELRCSPAFMGERYGLDPTRVLAAVCRGVRAGMARYPVQAQIIGIMSRHMGEESCWR
ELEAAIALMSEGVVGIDLAGDEANFPGTRFVKHFARARAAGLRITVHAGEAAGAWSVRQAIEELGAERIGHGVRAVEDPA
VLQLIAERGVALEVCPTSNVQTQTVSGYESHPLPQLLRRGLLVTLNTDDPGISAIDLPHEYRIARDRLGLTTEELRTLQA
HALSAAFIDEATRAALLHKARSRTT

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=344, Percent_Identity=33.4302325581395, Blast_Score=166, Evalue=3e-41,
Organism=Escherichia coli, GI1787910, Length=329, Percent_Identity=46.2006079027356, Blast_Score=300, Evalue=7e-83,
Organism=Caenorhabditis elegans, GI17538512, Length=341, Percent_Identity=31.0850439882698, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI32565969, Length=341, Percent_Identity=31.0850439882698, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115537133, Length=342, Percent_Identity=26.6081871345029, Blast_Score=86, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6324188, Length=331, Percent_Identity=23.2628398791541, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24645260, Length=324, Percent_Identity=25.3086419753086, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI45553183, Length=314, Percent_Identity=26.1146496815287, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI17737615, Length=314, Percent_Identity=26.1146496815287, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24666073, Length=291, Percent_Identity=24.3986254295533, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19922262, Length=317, Percent_Identity=24.6056782334385, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37650; Mature: 37518

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQAQADTAPIARDVPLIDLHRHLDGNVRLTTILDVARTYGIRLPADTVEGLRPYAQIQ
CCCCCCCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHHCCCCCHHHHHHCCHHHHHH
GVAASVMDFIARFDLLKLICVDEDVVARIAEENVEDAANEGIDYIELRCSPAFMGERYGL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCC
DPTRVLAAVCRGVRAGMARYPVQAQIIGIMSRHMGEESCWRELEAAIALMSEGVVGIDLA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEC
GDEANFPGTRFVKHFARARAAGLRITVHAGEAAGAWSVRQAIEELGAERIGHGVRAVEDP
CCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCH
AVLQLIAERGVALEVCPTSNVQTQTVSGYESHPLPQLLRRGLLVTLNTDDPGISAIDLPH
HHHHHHHHCCCEEEECCCCCCCEEECCCCCCCCHHHHHHCCEEEEECCCCCCCEEECCCH
EYRIARDRLGLTTEELRTLQAHALSAAFIDEATRAALLHKARSRTT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TLQAQADTAPIARDVPLIDLHRHLDGNVRLTTILDVARTYGIRLPADTVEGLRPYAQIQ
CCCCCCCCCCCCCCCCHHHHHHCCCCCEEEHHHHHHHHHHCCCCCHHHHHHCCHHHHHH
GVAASVMDFIARFDLLKLICVDEDVVARIAEENVEDAANEGIDYIELRCSPAFMGERYGL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCCCC
DPTRVLAAVCRGVRAGMARYPVQAQIIGIMSRHMGEESCWRELEAAIALMSEGVVGIDLA
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEC
GDEANFPGTRFVKHFARARAAGLRITVHAGEAAGAWSVRQAIEELGAERIGHGVRAVEDP
CCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCH
AVLQLIAERGVALEVCPTSNVQTQTVSGYESHPLPQLLRRGLLVTLNTDDPGISAIDLPH
HHHHHHHHCCCEEEECCCCCCCEEECCCCCCCCHHHHHHCCEEEEECCCCCCCEEECCCH
EYRIARDRLGLTTEELRTLQAHALSAAFIDEATRAALLHKARSRTT
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA