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The map label for this gene is nhaA2 [H]

Identifier: 222526649

GI number: 222526649

Start: 4257874

End: 4258662

Strand: Reverse

Name: nhaA2 [H]

Synonym: Chy400_3418

Alternate gene names: 222526649

Gene position: 4258662-4257874 (Counterclockwise)

Preceding gene: 222526650

Following gene: 222526648

Centisome position: 80.83

GC content: 56.15

Gene sequence:

>789_bases
ATGAAATACGTTCCAGTATATTACCTTCACGACAAAATTATGCGCTTTTCTTTACTCCTGATACTCGTGTTCGTTGTGAC
CGGCTGTGGCAGTGCAGTACCACCAGTACCGACCCGCTCGGCAGTGGAACTTCGCCAGACTCAGGTAGCCTTGCAAGGTT
TGCCTACCGTTCCCCCGGCCCCAACTGAACTGAGCCGTCCGACACCTACTCCTGCGCCACCTGTTGATTTGGTCGAACTG
CTGAAGCTCACCGACGACGATCCACGGGCGATGGGTGATCCGAATGCACCGGTGCTTATGATCGAGTTTACCGATTATGA
GTGTCCATTTTGTGCCCGCTTCGTTAGTGAGTCGCGCCCCCGGATTGTGCGCGAATTCGTTGAAACTGGCGTTGTCAGGC
TCGTTGTACGTGACTTTCCGCTGACTTCGATCCACCCTTCGGCATTACTGGCAGCCGGCGTGGCCCATTGCGCCGCTGCA
CAGGGGCAGTTCTGGCCGGTGTATGAGATGCTGTTTCAAACCCACAATGTTGAGTGGGGCGGGGTGCCCAATCGTGACCG
GGATGTGTTGATCGAGCTGGCCGGAAAACTCGGTGTGGATACAGCGCAGTTGCGTGCCTGTCTCGACGATCCGGCGACTG
AGGCGACTATCATCGCCGAGGTTGAGACGGCTACCCGCCTGGGAATTAACTCAACGCCGAACTTTATCATTAACGGTCGG
ATTGTGCGTGGTGCGTTTCCGTTCGAGAGTTTTGCCAGTCTGATCCGACGGTTGGCCGAACTGCCGTGA

Upstream 100 bases:

>100_bases
TGCCATACCGGTAGACTGGGAGCATGATATACTGTCGTTAGTGATTGGCAAGGGTTCATGCGCCTGTGCGATGGTCGGGT
AGCACGGCCACTCAGTTTGT

Downstream 100 bases:

>100_bases
GTCTTCCGCTTTGATCCCTCTCTGGATTGGCAGGGGCGAGCAGGTGGCCGGCGTATGCTATACGCCCCTGGCAGATGGAC
ACGGAAGTGATGCGTCTATA

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA 2 [H]

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKYVPVYYLHDKIMRFSLLLILVFVVTGCGSAVPPVPTRSAVELRQTQVALQGLPTVPPAPTELSRPTPTPAPPVDLVEL
LKLTDDDPRAMGDPNAPVLMIEFTDYECPFCARFVSESRPRIVREFVETGVVRLVVRDFPLTSIHPSALLAAGVAHCAAA
QGQFWPVYEMLFQTHNVEWGGVPNRDRDVLIELAGKLGVDTAQLRACLDDPATEATIIAEVETATRLGINSTPNFIINGR
IVRGAFPFESFASLIRRLAELP

Sequences:

>Translated_262_residues
MKYVPVYYLHDKIMRFSLLLILVFVVTGCGSAVPPVPTRSAVELRQTQVALQGLPTVPPAPTELSRPTPTPAPPVDLVEL
LKLTDDDPRAMGDPNAPVLMIEFTDYECPFCARFVSESRPRIVREFVETGVVRLVVRDFPLTSIHPSALLAAGVAHCAAA
QGQFWPVYEMLFQTHNVEWGGVPNRDRDVLIELAGKLGVDTAQLRACLDDPATEATIIAEVETATRLGINSTPNFIINGR
IVRGAFPFESFASLIRRLAELP
>Mature_262_residues
MKYVPVYYLHDKIMRFSLLLILVFVVTGCGSAVPPVPTRSAVELRQTQVALQGLPTVPPAPTELSRPTPTPAPPVDLVEL
LKLTDDDPRAMGDPNAPVLMIEFTDYECPFCARFVSESRPRIVREFVETGVVRLVVRDFPLTSIHPSALLAAGVAHCAAA
QGQFWPVYEMLFQTHNVEWGGVPNRDRDVLIELAGKLGVDTAQLRACLDDPATEATIIAEVETATRLGINSTPNFIINGR
IVRGAFPFESFASLIRRLAELP

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 28758; Mature: 28758

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYVPVYYLHDKIMRFSLLLILVFVVTGCGSAVPPVPTRSAVELRQTQVALQGLPTVPPA
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
PTELSRPTPTPAPPVDLVELLKLTDDDPRAMGDPNAPVLMIEFTDYECPFCARFVSESRP
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCH
RIVREFVETGVVRLVVRDFPLTSIHPSALLAAGVAHCAAAQGQFWPVYEMLFQTHNVEWG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
GVPNRDRDVLIELAGKLGVDTAQLRACLDDPATEATIIAEVETATRLGINSTPNFIINGR
CCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHCCCCCCCCEEEECE
IVRGAFPFESFASLIRRLAELP
EEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYVPVYYLHDKIMRFSLLLILVFVVTGCGSAVPPVPTRSAVELRQTQVALQGLPTVPPA
CCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
PTELSRPTPTPAPPVDLVELLKLTDDDPRAMGDPNAPVLMIEFTDYECPFCARFVSESRP
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCH
RIVREFVETGVVRLVVRDFPLTSIHPSALLAAGVAHCAAAQGQFWPVYEMLFQTHNVEWG
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCC
GVPNRDRDVLIELAGKLGVDTAQLRACLDDPATEATIIAEVETATRLGINSTPNFIINGR
CCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEEEHHHHHCCCCCCCCEEEECE
IVRGAFPFESFASLIRRLAELP
EEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]