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The map label for this gene is ywlC [H]

Identifier: 222526643

GI number: 222526643

Start: 4250856

End: 4251911

Strand: Reverse

Name: ywlC [H]

Synonym: Chy400_3412

Alternate gene names: 222526643

Gene position: 4251911-4250856 (Counterclockwise)

Preceding gene: 222526644

Following gene: 222526642

Centisome position: 80.7

GC content: 63.64

Gene sequence:

>1056_bases
ATGCATACCAAACGGCTCGACACCTCACCCGCTGCAATTGCCATGGCCGGCGAACTCCTCCGGCGTGGCGAACTTGTCGC
CTTCCCGACCGAAACGGTCTACGGGCTAGGCGGGCATGCGCTCGACGAGCGTGCCGTAGCGGCCATTTTTACCGCGAAGG
GGCGTCCGGCGAATGATCCGCTGATCGTCCACATCACGGCAGCCACCGATCTGCCACTGGTGGCTGCGACAGTTCCACCA
CTTGCCGGCAGGCTGGCAGCGGCCTGCTGGCCAGGCCCACTCACGCTGATCGTACCGCGCCATCCTCGTGTACCGTTGAC
AGTGACTGCCGGACGTGAAACGGTCGCGGTACGGGTACCTTCACATCCGATTGCCCAGGAGCTGCTGCGGGCTGCCGGTG
TACCGGTTGCCGCACCAAGTGCCAACCGCTTCGGACACACCAGTCCAACCACTGCCGATCACGTGCTGGCTGATCTCGAT
GGACGGATCGCGGCGGTGATTGATGGTGGGGCGACGCCGATTGGCATTGAGTCAACCGTGCTCGACTGCACCACCGATCC
GCCGACACTTTTGCGCCCTGGCGGGATTAGCCTTGAAACGTTGACCGACCTGATCGGCGAGGTGCAACTCCGTTCACAAC
CTACCGCCGATGAAGCGCATGGCCTGACCGCGCCCGGTCTCCTGGAGCGCCACTATGCCCCCGATCACGAATTATGGTTG
TTTAGTGGCAAACCGGACTCGGTTCTCGCCCGGCTACGCGCCGAAACCGAAGCAGCGCTGGCCCGTGGACTGCGCGTTGG
TCTCCTTTTGCCAGAGGAAGACCTCGCGCTGATGCACGACTTACCAGTTGAGCGGGAATCGCTCGGCCCAACTTCTGATC
CGGCGATCATTGCCCGGCGGCTATACGCCGCGCTGCGGGCGCTTGACGAACGCCAGCCCGATCGCATGTTTACCCGCGAT
CTCGACGAAGCCGGCCTGGGGCGTGCCCTGCGGGATCGCCTGCGCCGTGCGGCAACGCGGGTGATTGTGGTTGACGAAGA
GACGGGAAAACAGTAA

Upstream 100 bases:

>100_bases
GCCGATTGCGCGCTGCGCCGCCCGAAGAACAGGGCGAATTGGAAACGGTTTTGTTGATGTCAATCAACGGCATTGCTGCC
GGATTGAAGAATACAGGCTG

Downstream 100 bases:

>100_bases
AATACGAAACAATGTTCTTATTTTGTAGCAAGGCTGCGACGCTATGGACAACAACACAACGCTCATCCTGGGTGATTGTC
GTGACGTTCTCAAAGATATA

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MHTKRLDTSPAAIAMAGELLRRGELVAFPTETVYGLGGHALDERAVAAIFTAKGRPANDPLIVHITAATDLPLVAATVPP
LAGRLAAACWPGPLTLIVPRHPRVPLTVTAGRETVAVRVPSHPIAQELLRAAGVPVAAPSANRFGHTSPTTADHVLADLD
GRIAAVIDGGATPIGIESTVLDCTTDPPTLLRPGGISLETLTDLIGEVQLRSQPTADEAHGLTAPGLLERHYAPDHELWL
FSGKPDSVLARLRAETEAALARGLRVGLLLPEEDLALMHDLPVERESLGPTSDPAIIARRLYAALRALDERQPDRMFTRD
LDEAGLGRALRDRLRRAATRVIVVDEETGKQ

Sequences:

>Translated_351_residues
MHTKRLDTSPAAIAMAGELLRRGELVAFPTETVYGLGGHALDERAVAAIFTAKGRPANDPLIVHITAATDLPLVAATVPP
LAGRLAAACWPGPLTLIVPRHPRVPLTVTAGRETVAVRVPSHPIAQELLRAAGVPVAAPSANRFGHTSPTTADHVLADLD
GRIAAVIDGGATPIGIESTVLDCTTDPPTLLRPGGISLETLTDLIGEVQLRSQPTADEAHGLTAPGLLERHYAPDHELWL
FSGKPDSVLARLRAETEAALARGLRVGLLLPEEDLALMHDLPVERESLGPTSDPAIIARRLYAALRALDERQPDRMFTRD
LDEAGLGRALRDRLRRAATRVIVVDEETGKQ
>Mature_351_residues
MHTKRLDTSPAAIAMAGELLRRGELVAFPTETVYGLGGHALDERAVAAIFTAKGRPANDPLIVHITAATDLPLVAATVPP
LAGRLAAACWPGPLTLIVPRHPRVPLTVTAGRETVAVRVPSHPIAQELLRAAGVPVAAPSANRFGHTSPTTADHVLADLD
GRIAAVIDGGATPIGIESTVLDCTTDPPTLLRPGGISLETLTDLIGEVQLRSQPTADEAHGLTAPGLLERHYAPDHELWL
FSGKPDSVLARLRAETEAALARGLRVGLLLPEEDLALMHDLPVERESLGPTSDPAIIARRLYAALRALDERQPDRMFTRD
LDEAGLGRALRDRLRRAATRVIVVDEETGKQ

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI87081864, Length=188, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI2367210, Length=150, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17537239, Length=212, Percent_Identity=32.0754716981132, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321269, Length=379, Percent_Identity=35.6200527704486, Blast_Score=201, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 37356; Mature: 37356

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTKRLDTSPAAIAMAGELLRRGELVAFPTETVYGLGGHALDERAVAAIFTAKGRPANDP
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHEEEEEEECCCCCCCC
LIVHITAATDLPLVAATVPPLAGRLAAACWPGPLTLIVPRHPRVPLTVTAGRETVAVRVP
EEEEEEECCCCCEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCEEEEEECC
SHPIAQELLRAAGVPVAAPSANRFGHTSPTTADHVLADLDGRIAAVIDGGATPIGIESTV
CCHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCEE
LDCTTDPPTLLRPGGISLETLTDLIGEVQLRSQPTADEAHGLTAPGLLERHYAPDHELWL
EECCCCCCCEECCCCCCHHHHHHHHHHEEECCCCCCHHHCCCCCCCHHHHCCCCCCCEEE
FSGKPDSVLARLRAETEAALARGLRVGLLLPEEDLALMHDLPVERESLGPTSDPAIIARR
ECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCHHHCCCCCCHHHHHHH
LYAALRALDERQPDRMFTRDLDEAGLGRALRDRLRRAATRVIVVDEETGKQ
HHHHHHHHHCCCCHHHHHHCCCHHHCCHHHHHHHHHHHEEEEEEECCCCCC
>Mature Secondary Structure
MHTKRLDTSPAAIAMAGELLRRGELVAFPTETVYGLGGHALDERAVAAIFTAKGRPANDP
CCCCCCCCCCHHHHHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHEEEEEEECCCCCCCC
LIVHITAATDLPLVAATVPPLAGRLAAACWPGPLTLIVPRHPRVPLTVTAGRETVAVRVP
EEEEEEECCCCCEEEECCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEECCCEEEEEECC
SHPIAQELLRAAGVPVAAPSANRFGHTSPTTADHVLADLDGRIAAVIDGGATPIGIESTV
CCHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCEE
LDCTTDPPTLLRPGGISLETLTDLIGEVQLRSQPTADEAHGLTAPGLLERHYAPDHELWL
EECCCCCCCEECCCCCCHHHHHHHHHHEEECCCCCCHHHCCCCCCCHHHHCCCCCCCEEE
FSGKPDSVLARLRAETEAALARGLRVGLLLPEEDLALMHDLPVERESLGPTSDPAIIARR
ECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHCCCCCHHHCCCCCCHHHHHHH
LYAALRALDERQPDRMFTRDLDEAGLGRALRDRLRRAATRVIVVDEETGKQ
HHHHHHHHHCCCCHHHHHHCCCHHHCCHHHHHHHHHHHEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]