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The map label for this gene is aroK [H]

Identifier: 222526604

GI number: 222526604

Start: 4202436

End: 4202969

Strand: Direct

Name: aroK [H]

Synonym: Chy400_3372

Alternate gene names: 222526604

Gene position: 4202436-4202969 (Clockwise)

Preceding gene: 222526603

Following gene: 222526606

Centisome position: 79.76

GC content: 61.24

Gene sequence:

>534_bases
ATGGTGTGGGATCCAAACTGGCTGGATCGGCCTGTAGCACTGGTTGGTTTAAGTGGATGTGGCAAGTCAACCCTGGCCCG
GTTGCTGGCACGCGCCCTGAGCTGGCCCTGGTACGATACCGACGCGGCGATTGCCGCCGCCGCCGGTATGAGTGTGGCCG
ATCTGTTTCAGACCTATGGCGAGGCCGAGTTTCGCGTGCGCGAGACAGCCGCGCTGACCGAAGCACTGCGTGAAGCGCAG
GTGATTGCTACCGGCGGTGGCATTGTCTTGCAGCCGGAAAACCGACGTATGCTGCGCGAATATGCGACGGTGATCTGGCT
GGATGCTGCTGATGCGACGATCCTGACCCGGCTGGCTGCCGATGCCGAACAACGCCCATTGTTGCACGGCGATGCCGCAG
CGCGACTGGCCGAATTACGTGCGCGACGTACACCGTTGTATGCTGAAGTGGCTGATGTAATCATCGCCACCGATGGCAAA
ACACCGCTTGAACTGGTGCAGCAGGTGATAGCGGCGCTTCGTCAGGGGCGATAG

Upstream 100 bases:

>100_bases
GATTATCGCGGCAGCAGTTGCATATGCTTTATCGGCTTTTGTGATCTGGAGCCTGCGCCTGCAACGGATCGCAGCGCAGC
CCACTGCATAGGAGCAGGTT

Downstream 100 bases:

>100_bases
AGCAGGTCAACAAGTTGACATAATAATATCCAGGACAGACAACCCCGGTTGTCTGCCCTGGATGCAGATTCATTAGCGTT
CTTTTCAACCGCGATAGTTG

Product: Shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MVWDPNWLDRPVALVGLSGCGKSTLARLLARALSWPWYDTDAAIAAAAGMSVADLFQTYGEAEFRVRETAALTEALREAQ
VIATGGGIVLQPENRRMLREYATVIWLDAADATILTRLAADAEQRPLLHGDAAARLAELRARRTPLYAEVADVIIATDGK
TPLELVQQVIAALRQGR

Sequences:

>Translated_177_residues
MVWDPNWLDRPVALVGLSGCGKSTLARLLARALSWPWYDTDAAIAAAAGMSVADLFQTYGEAEFRVRETAALTEALREAQ
VIATGGGIVLQPENRRMLREYATVIWLDAADATILTRLAADAEQRPLLHGDAAARLAELRARRTPLYAEVADVIIATDGK
TPLELVQQVIAALRQGR
>Mature_177_residues
MVWDPNWLDRPVALVGLSGCGKSTLARLLARALSWPWYDTDAAIAAAAGMSVADLFQTYGEAEFRVRETAALTEALREAQ
VIATGGGIVLQPENRRMLREYATVIWLDAADATILTRLAADAEQRPLLHGDAAARLAELRARRTPLYAEVADVIIATDGK
TPLELVQQVIAALRQGR

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=168, Percent_Identity=39.8809523809524, Blast_Score=100, Evalue=4e-23,
Organism=Escherichia coli, GI1786587, Length=171, Percent_Identity=35.672514619883, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 19236; Mature: 19236

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWDPNWLDRPVALVGLSGCGKSTLARLLARALSWPWYDTDAAIAAAAGMSVADLFQTYG
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHC
EAEFRVRETAALTEALREAQVIATGGGIVLQPENRRMLREYATVIWLDAADATILTRLAA
CCHHHHHHHHHHHHHHHHHHEEEECCCEEECCCCHHHHHHHHHEEEECCCCHHHHHHHHH
DAEQRPLLHGDAAARLAELRARRTPLYAEVADVIIATDGKTPLELVQQVIAALRQGR
CHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVWDPNWLDRPVALVGLSGCGKSTLARLLARALSWPWYDTDAAIAAAAGMSVADLFQTYG
CCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHC
EAEFRVRETAALTEALREAQVIATGGGIVLQPENRRMLREYATVIWLDAADATILTRLAA
CCHHHHHHHHHHHHHHHHHHEEEECCCEEECCCCHHHHHHHHHEEEECCCCHHHHHHHHH
DAEQRPLLHGDAAARLAELRARRTPLYAEVADVIIATDGKTPLELVQQVIAALRQGR
CHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12663927 [H]