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The map label for this gene is pqqL [C]

Identifier: 222526086

GI number: 222526086

Start: 3508367

End: 3509638

Strand: Direct

Name: pqqL [C]

Synonym: Chy400_2843

Alternate gene names: 222526086

Gene position: 3508367-3509638 (Clockwise)

Preceding gene: 222526085

Following gene: 222526087

Centisome position: 66.59

GC content: 55.5

Gene sequence:

>1272_bases
ATGCCATACTTGCATACCACGCCTAACGGCATCCGCGTTTTAATCGAAGAACTGCCACACACCCATTCGGTTGCAGTTGG
TTGCTTCATTGACATCGGTGCGCGCTACGAATCGGCAGAACTGGCCGGTGCTGCCCACTTCATTGAACATATGCTCTTCA
AGGGAGCCGGTGCCTATCCAACCGCCCATGCGATCTCGCTGGCAATTGAGGGGATTGGTGGCTATCTTAACGCTTCCACT
GGCTACGAGACAACTGTTTTTTATGCGAAAGTTGCCGCTATCCATTTCCAACGAGCACTGCACGTGTTGAGCGAGATGGT
GCAACGGCCACTCTTCGATGCTACCGAATTAGAAAAAGAGCGGCGGGTGATTATCGAAGAGATTCGCGGCATCCAGGATA
ATCCCACCGAGCTTGTCCACGAACTGCTGCAACGCACAATGTGGGGCGATCATCCGTTTGGCCGCGATATTGCTGGAAGT
ATTGCTACCGTCAGCGCCATTGCCCGCCACGAGCTGTTGCAATTTTTCGCTCAGGGGTATCACGCCGGGAATCTGGTCGT
ATCGGTCGCCGGCAAGATTGCTGCCGAAGAGGCCATTCCCGCCATCGAACGCGCTTTTGCCGATCTCCCTGCCGCGCAGC
GTCCGGCGGCAATTGCCGCGCCTCCCTTACCGCACCAGCCCAAACTCAGCCTGCTCACACGTGACATCGAACAGGGCAAC
TTTTGCCTTGGCATGCCCGGCGTCTCGTACCACGATCCTGATCGCCGGGCAGTGCATGCGCTCGACGCCCTGCTCGGTGG
CGGTATGTCGTCGCGCCTGTTCCAGACGATCCGTGAAGAACACGGTCTCAGCTACAATATCGGTTCTTATCACAACGAAT
TTTCTGATACCGGTATGTGGGTTATTTATGCTGGGGTGGAGCCTGATGCATTGCGTGACGCGGTGGCAATGACCCGCGCT
ATAGTGCGCGATGTGGCCGAAAACGGCCCTACAAAGCAAGAGCTGGCAACCGTGAAAGAACAGCTCAAGGGCAGCTTGTT
ACTCTCGCTCGAAGATACCTGGTCGATTGCCTCGCGTAACGCTACCAGTCTGCTGCGTTATCAAATGGTGCCGCCGGTTG
AACAGATTATTGCCGAGATTGATGCATTGAGTTTAGCCGATCTCCAGCGTGCTGCCCGCCGGTTACTCACTGCCAATCAA
CAGTGGCTGGCGGTTGTTGGCCCATACAGCGACGAAGATCAGGCCGATTTACAGATATTGCTGGAAGAGTGA

Upstream 100 bases:

>100_bases
AACGCATGGAGATACCACCCTCACATGGCCAGCCGGCATCACGGCTGGAATTCTGGCGGCGCGAACAGTAATCGTGTTCT
GATCTGATAATGTGTAAACA

Downstream 100 bases:

>100_bases
GGTTGCACGGTGAAGAGTGTGGCAATTGTTGGCGCCGGTATAGCCGGGCTGGCTGCCGCTCAGGCGCTGATCGCCAATCA
AAGTGGGATTGTGCCGGTCG

Product: peptidase M16 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MPYLHTTPNGIRVLIEELPHTHSVAVGCFIDIGARYESAELAGAAHFIEHMLFKGAGAYPTAHAISLAIEGIGGYLNAST
GYETTVFYAKVAAIHFQRALHVLSEMVQRPLFDATELEKERRVIIEEIRGIQDNPTELVHELLQRTMWGDHPFGRDIAGS
IATVSAIARHELLQFFAQGYHAGNLVVSVAGKIAAEEAIPAIERAFADLPAAQRPAAIAAPPLPHQPKLSLLTRDIEQGN
FCLGMPGVSYHDPDRRAVHALDALLGGGMSSRLFQTIREEHGLSYNIGSYHNEFSDTGMWVIYAGVEPDALRDAVAMTRA
IVRDVAENGPTKQELATVKEQLKGSLLLSLEDTWSIASRNATSLLRYQMVPPVEQIIAEIDALSLADLQRAARRLLTANQ
QWLAVVGPYSDEDQADLQILLEE

Sequences:

>Translated_423_residues
MPYLHTTPNGIRVLIEELPHTHSVAVGCFIDIGARYESAELAGAAHFIEHMLFKGAGAYPTAHAISLAIEGIGGYLNAST
GYETTVFYAKVAAIHFQRALHVLSEMVQRPLFDATELEKERRVIIEEIRGIQDNPTELVHELLQRTMWGDHPFGRDIAGS
IATVSAIARHELLQFFAQGYHAGNLVVSVAGKIAAEEAIPAIERAFADLPAAQRPAAIAAPPLPHQPKLSLLTRDIEQGN
FCLGMPGVSYHDPDRRAVHALDALLGGGMSSRLFQTIREEHGLSYNIGSYHNEFSDTGMWVIYAGVEPDALRDAVAMTRA
IVRDVAENGPTKQELATVKEQLKGSLLLSLEDTWSIASRNATSLLRYQMVPPVEQIIAEIDALSLADLQRAARRLLTANQ
QWLAVVGPYSDEDQADLQILLEE
>Mature_422_residues
PYLHTTPNGIRVLIEELPHTHSVAVGCFIDIGARYESAELAGAAHFIEHMLFKGAGAYPTAHAISLAIEGIGGYLNASTG
YETTVFYAKVAAIHFQRALHVLSEMVQRPLFDATELEKERRVIIEEIRGIQDNPTELVHELLQRTMWGDHPFGRDIAGSI
ATVSAIARHELLQFFAQGYHAGNLVVSVAGKIAAEEAIPAIERAFADLPAAQRPAAIAAPPLPHQPKLSLLTRDIEQGNF
CLGMPGVSYHDPDRRAVHALDALLGGGMSSRLFQTIREEHGLSYNIGSYHNEFSDTGMWVIYAGVEPDALRDAVAMTRAI
VRDVAENGPTKQELATVKEQLKGSLLLSLEDTWSIASRNATSLLRYQMVPPVEQIIAEIDALSLADLQRAARRLLTANQQ
WLAVVGPYSDEDQADLQILLEE

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=412, Percent_Identity=27.6699029126214, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI46593007, Length=387, Percent_Identity=23.5142118863049, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI24308013, Length=440, Percent_Identity=22.7272727272727, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI155969707, Length=226, Percent_Identity=26.9911504424779, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1787770, Length=221, Percent_Identity=29.8642533936652, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367164, Length=203, Percent_Identity=25.1231527093596, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71999683, Length=424, Percent_Identity=26.4150943396226, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17553678, Length=406, Percent_Identity=21.9211822660099, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17510601, Length=431, Percent_Identity=21.8097447795824, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17557500, Length=191, Percent_Identity=27.2251308900524, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72001443, Length=191, Percent_Identity=26.7015706806283, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25146566, Length=191, Percent_Identity=27.2251308900524, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71994338, Length=191, Percent_Identity=27.2251308900524, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI25146563, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI32566665, Length=191, Percent_Identity=27.2251308900524, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=397, Percent_Identity=26.9521410579345, Blast_Score=169, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6321813, Length=420, Percent_Identity=24.2857142857143, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6323421, Length=223, Percent_Identity=25.5605381165919, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325379, Length=198, Percent_Identity=26.7676767676768, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357875, Length=411, Percent_Identity=26.2773722627737, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24646943, Length=411, Percent_Identity=26.2773722627737, Blast_Score=155, Evalue=6e-38,
Organism=Drosophila melanogaster, GI19921772, Length=425, Percent_Identity=23.2941176470588, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24641429, Length=205, Percent_Identity=27.8048780487805, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI221513245, Length=228, Percent_Identity=26.7543859649123, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24667786, Length=207, Percent_Identity=23.6714975845411, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 46332; Mature: 46201

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYLHTTPNGIRVLIEELPHTHSVAVGCFIDIGARYESAELAGAAHFIEHMLFKGAGAYP
CCCCCCCCHHHHHHHHHCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC
TAHAISLAIEGIGGYLNASTGYETTVFYAKVAAIHFQRALHVLSEMVQRPLFDATELEKE
HHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RRVIIEEIRGIQDNPTELVHELLQRTMWGDHPFGRDIAGSIATVSAIARHELLQFFAQGY
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
HAGNLVVSVAGKIAAEEAIPAIERAFADLPAAQRPAAIAAPPLPHQPKLSLLTRDIEQGN
CCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
FCLGMPGVSYHDPDRRAVHALDALLGGGMSSRLFQTIREEHGLSYNIGSYHNEFSDTGMW
EEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCEE
VIYAGVEPDALRDAVAMTRAIVRDVAENGPTKQELATVKEQLKGSLLLSLEDTWSIASRN
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHCC
ATSLLRYQMVPPVEQIIAEIDALSLADLQRAARRLLTANQQWLAVVGPYSDEDQADLQIL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEE
LEE
ECC
>Mature Secondary Structure 
PYLHTTPNGIRVLIEELPHTHSVAVGCFIDIGARYESAELAGAAHFIEHMLFKGAGAYP
CCCCCCCHHHHHHHHHCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCC
TAHAISLAIEGIGGYLNASTGYETTVFYAKVAAIHFQRALHVLSEMVQRPLFDATELEKE
HHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RRVIIEEIRGIQDNPTELVHELLQRTMWGDHPFGRDIAGSIATVSAIARHELLQFFAQGY
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
HAGNLVVSVAGKIAAEEAIPAIERAFADLPAAQRPAAIAAPPLPHQPKLSLLTRDIEQGN
CCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCC
FCLGMPGVSYHDPDRRAVHALDALLGGGMSSRLFQTIREEHGLSYNIGSYHNEFSDTGMW
EEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEECCCCCCCCCCCCCEE
VIYAGVEPDALRDAVAMTRAIVRDVAENGPTKQELATVKEQLKGSLLLSLEDTWSIASRN
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEECHHHHHHHCC
ATSLLRYQMVPPVEQIIAEIDALSLADLQRAARRLLTANQQWLAVVGPYSDEDQADLQIL
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEE
LEE
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]