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The map label for this gene is cbaA [H]

Identifier: 222525862

GI number: 222525862

Start: 3250323

End: 3252002

Strand: Direct

Name: cbaA [H]

Synonym: Chy400_2615

Alternate gene names: 222525862

Gene position: 3250323-3252002 (Clockwise)

Preceding gene: 222525861

Following gene: 222525863

Centisome position: 61.69

GC content: 55.77

Gene sequence:

>1680_bases
ATGGCCAGTATCGCAGCACGTGCTCGCCCGTTGGCAATCAGCGCCGACTTGAGCGTTGAGCGTAAGCTTGCCGGGATCAA
CATCTTCATCGCCTTTGCCGCGCTGGCAGTAGGCGGATTGATGGGTGTGTTGCAAATCCTGCGCTACAACGGGCTTGATC
TCTATACACCGGTCAAACCTGTCTTGCCCGGCGGCTACTACCAGGGTCTGACCGTTCACGGGGTCTTAAACGTTCTCGTT
TTCACCACCTTCTACATCATCGGCTTTTTGACCTACATCTTTGCTAAAGCTCTCAATCGCCCTCTCGCCAACAGCCGGCT
GGCGTGGGCCACGCTTTGGGTCATGGGTGCCGGTCTGGTGCTGGCAGCCATCCCATTGCTCACCAACAACGCAACCGTGA
TGTTTACCTTCTATCCACCGCTGAAAGCCGATGCACTCTTCTACATTGGGCTGACGCTGGTGGTGGCCGGTACCTGGTTG
TTGCTGGTGAACATGATTATTACCCGGAACGCATGGCTGGCCGATAATCCGGGTCAACGCACGCCACTGCCGGCATTTAT
GGCGATTGTGACGATGCTGATGTGGACGATTGCGACTATTGGTGTCGCCAGTGAGATGATCTTCCTGGTGATTCCGTGGT
CGCTGGGCCTGGTTGGCGGCACCGATCCGGTGCTGGCACGCACCCTCTTCTGGTTCACCGGTCACCCGATTGTCTACTTC
TGGCTGTTACCGGCGTACATTTCGTGGTACACGCTGGTACCTGAGCAGGCGGGTGGCAAGCTATTCAGCGATCCAATGGC
CCGTGTTTCATTCATTCTCTTCCTCATTCTGTCGATTCCCATCGGTATGCACCATCAGGTGACCGATCCGGGCATCTCCG
AGATTTGGAAACTGGTGCATGCCGTCTTTACTTTTGGCGTCTTCTTCCCCAGCCTGCTCACCTTCTTCAACGTTGTCGCC
TCACTAGAGTATGCGGGACGGCGTAACGGTGGTGAAGGCTGGCTGGCCTGGATTTTCAACCTGCCGTGGGGTAAACCTGA
GATTTCGGCCCAGATTGTGGCAATGATGCTCTTCGCTTTTGGCGGTATCAGCGGCCTGGTCAATGCCTCGTACAACGTTA
ACCTGGTTGTTCACAACACCGCGTGGATTTCCGGTCACTTCCACCTGACCGTCGGCACAGCAGTGGCGCTCAGCTTTATG
GGGATTACGTACTGGCTGGTACCGCACCTGACCGGACGTGCCCTGTGGAGCAAGAGTCTGGGTGTGGCGCAGGCGTGGCT
CTGGTTCGTGGGTATGGGCCTCTTCTCGCACTTCATGCACGAGCTGGGGCTGCGTGGCATGCCGCGCCGTACTGACATTG
GCGGTGCACCGTATGTACAAGACGAATGGCGCTTCTTCCTCTTCTTTGCCATGATCGGTGGCCTGATCATGTTTGTCAGC
GCCATCTTCTACTACCTCAATATGATAATGACGCTGACACGAGGAAAGAAGCTGGCTGAAGTTCCTGATATTACCTTTGC
GCGTGCCCTCTCCGGACCGGAAGATGCGCCAAAAATTCTCGACCGGTTGCTGGTATGGGTGGCAGTGGCGGCGGTGTTGA
TCTTGATCAACTATCTGCCGACGATTATTGACATCCTTAATACGGCAACCTTTGACATACCAGGACGGCGTGTCTGGTAA

Upstream 100 bases:

>100_bases
GTGTCACGAGTATTGTGGGGCCGGCCACCACGTCATGTTCGGTAAGGTCATTGTGAACTGAGCGATGGAGCGCTCGGCTG
GAATACAAGGAGAGAATTGC

Downstream 100 bases:

>100_bases
AGAACGCCGGTTCAGCGGAGAGACGAGGGGCAGGCAAACGCCTGCCTCTTTTCCTAATACGGCAACCTTCGACATACCAG
GACGGCGTGTCTGGTAAAGA

Product: Cytochrome-c oxidase

Products: NA

Alternate protein names: Cytochrome c ba(3) subunit I; Cytochrome c oxidase polypeptide I; Cytochrome cba3 subunit 1 [H]

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MASIAARARPLAISADLSVERKLAGINIFIAFAALAVGGLMGVLQILRYNGLDLYTPVKPVLPGGYYQGLTVHGVLNVLV
FTTFYIIGFLTYIFAKALNRPLANSRLAWATLWVMGAGLVLAAIPLLTNNATVMFTFYPPLKADALFYIGLTLVVAGTWL
LLVNMIITRNAWLADNPGQRTPLPAFMAIVTMLMWTIATIGVASEMIFLVIPWSLGLVGGTDPVLARTLFWFTGHPIVYF
WLLPAYISWYTLVPEQAGGKLFSDPMARVSFILFLILSIPIGMHHQVTDPGISEIWKLVHAVFTFGVFFPSLLTFFNVVA
SLEYAGRRNGGEGWLAWIFNLPWGKPEISAQIVAMMLFAFGGISGLVNASYNVNLVVHNTAWISGHFHLTVGTAVALSFM
GITYWLVPHLTGRALWSKSLGVAQAWLWFVGMGLFSHFMHELGLRGMPRRTDIGGAPYVQDEWRFFLFFAMIGGLIMFVS
AIFYYLNMIMTLTRGKKLAEVPDITFARALSGPEDAPKILDRLLVWVAVAAVLILINYLPTIIDILNTATFDIPGRRVW

Sequences:

>Translated_559_residues
MASIAARARPLAISADLSVERKLAGINIFIAFAALAVGGLMGVLQILRYNGLDLYTPVKPVLPGGYYQGLTVHGVLNVLV
FTTFYIIGFLTYIFAKALNRPLANSRLAWATLWVMGAGLVLAAIPLLTNNATVMFTFYPPLKADALFYIGLTLVVAGTWL
LLVNMIITRNAWLADNPGQRTPLPAFMAIVTMLMWTIATIGVASEMIFLVIPWSLGLVGGTDPVLARTLFWFTGHPIVYF
WLLPAYISWYTLVPEQAGGKLFSDPMARVSFILFLILSIPIGMHHQVTDPGISEIWKLVHAVFTFGVFFPSLLTFFNVVA
SLEYAGRRNGGEGWLAWIFNLPWGKPEISAQIVAMMLFAFGGISGLVNASYNVNLVVHNTAWISGHFHLTVGTAVALSFM
GITYWLVPHLTGRALWSKSLGVAQAWLWFVGMGLFSHFMHELGLRGMPRRTDIGGAPYVQDEWRFFLFFAMIGGLIMFVS
AIFYYLNMIMTLTRGKKLAEVPDITFARALSGPEDAPKILDRLLVWVAVAAVLILINYLPTIIDILNTATFDIPGRRVW
>Mature_558_residues
ASIAARARPLAISADLSVERKLAGINIFIAFAALAVGGLMGVLQILRYNGLDLYTPVKPVLPGGYYQGLTVHGVLNVLVF
TTFYIIGFLTYIFAKALNRPLANSRLAWATLWVMGAGLVLAAIPLLTNNATVMFTFYPPLKADALFYIGLTLVVAGTWLL
LVNMIITRNAWLADNPGQRTPLPAFMAIVTMLMWTIATIGVASEMIFLVIPWSLGLVGGTDPVLARTLFWFTGHPIVYFW
LLPAYISWYTLVPEQAGGKLFSDPMARVSFILFLILSIPIGMHHQVTDPGISEIWKLVHAVFTFGVFFPSLLTFFNVVAS
LEYAGRRNGGEGWLAWIFNLPWGKPEISAQIVAMMLFAFGGISGLVNASYNVNLVVHNTAWISGHFHLTVGTAVALSFMG
ITYWLVPHLTGRALWSKSLGVAQAWLWFVGMGLFSHFMHELGLRGMPRRTDIGGAPYVQDEWRFFLFFAMIGGLIMFVSA
IFYYLNMIMTLTRGKKLAEVPDITFARALSGPEDAPKILDRLLVWVAVAAVLILINYLPTIIDILNTATFDIPGRRVW

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. This Ubiquinol Oxidase Shows Proton Pump Activity Across The Membrane In Addition To The Electron T

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=239, Percent_Identity=27.1966527196653, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6226519, Length=399, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 61779; Mature: 61648

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASIAARARPLAISADLSVERKLAGINIFIAFAALAVGGLMGVLQILRYNGLDLYTPVKP
CCCCHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VLPGGYYQGLTVHGVLNVLVFTTFYIIGFLTYIFAKALNRPLANSRLAWATLWVMGAGLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LAAIPLLTNNATVMFTFYPPLKADALFYIGLTLVVAGTWLLLVNMIITRNAWLADNPGQR
HHHHHHEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TPLPAFMAIVTMLMWTIATIGVASEMIFLVIPWSLGLVGGTDPVLARTLFWFTGHPIVYF
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHH
WLLPAYISWYTLVPEQAGGKLFSDPMARVSFILFLILSIPIGMHHQVTDPGISEIWKLVH
HHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AVFTFGVFFPSLLTFFNVVASLEYAGRRNGGEGWLAWIFNLPWGKPEISAQIVAMMLFAF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
GGISGLVNASYNVNLVVHNTAWISGHFHLTVGTAVALSFMGITYWLVPHLTGRALWSKSL
CCHHHHEECCEEEEEEEEEEEEEECEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAQAWLWFVGMGLFSHFMHELGLRGMPRRTDIGGAPYVQDEWRFFLFFAMIGGLIMFVS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AIFYYLNMIMTLTRGKKLAEVPDITFARALSGPEDAPKILDRLLVWVAVAAVLILINYLP
HHHHHHHHHHHHHCCCCHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TIIDILNTATFDIPGRRVW
HHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
ASIAARARPLAISADLSVERKLAGINIFIAFAALAVGGLMGVLQILRYNGLDLYTPVKP
CCCHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
VLPGGYYQGLTVHGVLNVLVFTTFYIIGFLTYIFAKALNRPLANSRLAWATLWVMGAGLV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
LAAIPLLTNNATVMFTFYPPLKADALFYIGLTLVVAGTWLLLVNMIITRNAWLADNPGQR
HHHHHHEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
TPLPAFMAIVTMLMWTIATIGVASEMIFLVIPWSLGLVGGTDPVLARTLFWFTGHPIVYF
CCHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCHHHHHHHHHHCCCHHHHH
WLLPAYISWYTLVPEQAGGKLFSDPMARVSFILFLILSIPIGMHHQVTDPGISEIWKLVH
HHHHHHHHHHHCCCHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AVFTFGVFFPSLLTFFNVVASLEYAGRRNGGEGWLAWIFNLPWGKPEISAQIVAMMLFAF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHH
GGISGLVNASYNVNLVVHNTAWISGHFHLTVGTAVALSFMGITYWLVPHLTGRALWSKSL
CCHHHHEECCEEEEEEEEEEEEEECEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVAQAWLWFVGMGLFSHFMHELGLRGMPRRTDIGGAPYVQDEWRFFLFFAMIGGLIMFVS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AIFYYLNMIMTLTRGKKLAEVPDITFARALSGPEDAPKILDRLLVWVAVAAVLILINYLP
HHHHHHHHHHHHHCCCCHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TIIDILNTATFDIPGRRVW
HHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7657607; 10338009; 10775261 [H]