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The map label for this gene is fabD [H]

Identifier: 222525841

GI number: 222525841

Start: 3228251

End: 3229207

Strand: Direct

Name: fabD [H]

Synonym: Chy400_2594

Alternate gene names: 222525841

Gene position: 3228251-3229207 (Clockwise)

Preceding gene: 222525840

Following gene: 222525842

Centisome position: 61.27

GC content: 54.55

Gene sequence:

>957_bases
ATGAGTATTGCGTGGGTATTCCCTGGTCAGGGATCGCAAGTCGTAGGCATGGGTCGTGATCTGATTGCAGCATCACCCGC
CGCACGTCAGATCTTTGCTACAGCGGACGAAACGCTTGATTTCAACCTGAGTGAATTGTGTTTTTGTGGGCCAGAAGCCG
ACCTTACCGCCACTGCAAATGCTCAACCGGCGCTGCTTACCACCAGCATGGCCTTACTGGCTGCAATGACCGAATTGTTG
GGAGATCGCCTTGAACAACCGATTGCCGTAGCCGGTCATAGCCTGGGTGAATACTCGGCGTTGGTGGCCGGTGGTGCACT
TGACTTCAAGACCGCTCTGCAACTTGTACGACGACGAGGTGAATTAATGGCCGCTGCCCACGAAGGGAGTATGGCCGCAG
TTATTGGCCTCGATGCCGCTATTCTCGAACAGATCTGTCAAGAAGTCAGTGCTGCACTGCAAAACGATCATTCTCATGGC
ACCGTTGTGATCGCTAACTATAACGCTCCCGACCAACTGGTCATCAGTGGTAGTGTCGTGGCTGTGGAGCATGCCAGTAT
GCTGGCTAAAAGCCGTGGTGCCAAACGGGTCATTCCGCTCAAGGTGAGTGCTGCCTTCCATTCCCCTCTCATGATCGAAG
CTGCTGAAGGAATGGCTCAGGCTATTGCTCATGCCACCGTGCGTAACCTCTCCATCCCTTTAATTGCCAATGTCACAGCC
GAACCGTTGTACGACGCCGATGATGTCCGGCGCGAGATCGTCGCACAGGTTGTCGCTCCGGTGCGCTGGATTGCCTCGGT
ACAACGAATGGTTGACCTCGGAGTCGAAACGTTTATCGAAATCGGGCCAGGAAAAGTGCTTACCGGCCTGATCCGCCGTA
TTGCTCCGACAGCGCGGCTGATTAATGTGGCGACATTTGAGGATGTCCGGGCGCTAACTGCAATGCAACCTGTATAG

Upstream 100 bases:

>100_bases
AAACCAGAGCATCTGGAATAGCGCGAAACCGTCACGCCGGTGCACGCAAGGGGGGGAGGAAACAGGTCGTGTCGGCAGAG
CAGGAAGAGGCAAACAGACC

Downstream 100 bases:

>100_bases
AGCATAGTATGGAATTACAAGGTCAGGTTGCTATTGTTACCGGTGGTGCACGCGGAATTGGGCGTGCCACGACAATCGAG
CTGGCTAACGCTGGCGCACG

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSIAWVFPGQGSQVVGMGRDLIAASPAARQIFATADETLDFNLSELCFCGPEADLTATANAQPALLTTSMALLAAMTELL
GDRLEQPIAVAGHSLGEYSALVAGGALDFKTALQLVRRRGELMAAAHEGSMAAVIGLDAAILEQICQEVSAALQNDHSHG
TVVIANYNAPDQLVISGSVVAVEHASMLAKSRGAKRVIPLKVSAAFHSPLMIEAAEGMAQAIAHATVRNLSIPLIANVTA
EPLYDADDVRREIVAQVVAPVRWIASVQRMVDLGVETFIEIGPGKVLTGLIRRIAPTARLINVATFEDVRALTAMQPV

Sequences:

>Translated_318_residues
MSIAWVFPGQGSQVVGMGRDLIAASPAARQIFATADETLDFNLSELCFCGPEADLTATANAQPALLTTSMALLAAMTELL
GDRLEQPIAVAGHSLGEYSALVAGGALDFKTALQLVRRRGELMAAAHEGSMAAVIGLDAAILEQICQEVSAALQNDHSHG
TVVIANYNAPDQLVISGSVVAVEHASMLAKSRGAKRVIPLKVSAAFHSPLMIEAAEGMAQAIAHATVRNLSIPLIANVTA
EPLYDADDVRREIVAQVVAPVRWIASVQRMVDLGVETFIEIGPGKVLTGLIRRIAPTARLINVATFEDVRALTAMQPV
>Mature_317_residues
SIAWVFPGQGSQVVGMGRDLIAASPAARQIFATADETLDFNLSELCFCGPEADLTATANAQPALLTTSMALLAAMTELLG
DRLEQPIAVAGHSLGEYSALVAGGALDFKTALQLVRRRGELMAAAHEGSMAAVIGLDAAILEQICQEVSAALQNDHSHGT
VVIANYNAPDQLVISGSVVAVEHASMLAKSRGAKRVIPLKVSAAFHSPLMIEAAEGMAQAIAHATVRNLSIPLIANVTAE
PLYDADDVRREIVAQVVAPVRWIASVQRMVDLGVETFIEIGPGKVLTGLIRRIAPTARLINVATFEDVRALTAMQPV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=295, Percent_Identity=32.2033898305085, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI27477045, Length=104, Percent_Identity=43.2692307692308, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI1787334, Length=299, Percent_Identity=43.1438127090301, Blast_Score=201, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=29.0102389078498, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=300, Percent_Identity=28, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=36.241610738255, Blast_Score=162, Evalue=3e-40,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33445; Mature: 33314

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIAWVFPGQGSQVVGMGRDLIAASPAARQIFATADETLDFNLSELCFCGPEADLTATAN
CEEEEEECCCCCEEEECCCHHHHCCHHHHHHHHCCCCCCCCCHHHHEEECCCCCCEEECC
AQPALLTTSMALLAAMTELLGDRLEQPIAVAGHSLGEYSALVAGGALDFKTALQLVRRRG
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
ELMAAAHEGSMAAVIGLDAAILEQICQEVSAALQNDHSHGTVVIANYNAPDQLVISGSVV
HHEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCEE
AVEHASMLAKSRGAKRVIPLKVSAAFHSPLMIEAAEGMAQAIAHATVRNLSIPLIANVTA
EHHHHHHHHHCCCCCEEEEEEEEHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCEEECCCC
EPLYDADDVRREIVAQVVAPVRWIASVQRMVDLGVETFIEIGPGKVLTGLIRRIAPTARL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHCCHHHH
INVATFEDVRALTAMQPV
EEHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SIAWVFPGQGSQVVGMGRDLIAASPAARQIFATADETLDFNLSELCFCGPEADLTATAN
EEEEEECCCCCEEEECCCHHHHCCHHHHHHHHCCCCCCCCCHHHHEEECCCCCCEEECC
AQPALLTTSMALLAAMTELLGDRLEQPIAVAGHSLGEYSALVAGGALDFKTALQLVRRRG
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHH
ELMAAAHEGSMAAVIGLDAAILEQICQEVSAALQNDHSHGTVVIANYNAPDQLVISGSVV
HHEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCEE
AVEHASMLAKSRGAKRVIPLKVSAAFHSPLMIEAAEGMAQAIAHATVRNLSIPLIANVTA
EHHHHHHHHHCCCCCEEEEEEEEHHHCCCEEEEHHHHHHHHHHHHHHHHCCCCEEECCCC
EPLYDADDVRREIVAQVVAPVRWIASVQRMVDLGVETFIEIGPGKVLTGLIRRIAPTARL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHCCHHHH
INVATFEDVRALTAMQPV
EEHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]