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The map label for this gene is mhpD [H]

Identifier: 222524750

GI number: 222524750

Start: 1871795

End: 1872529

Strand: Direct

Name: mhpD [H]

Synonym: Chy400_1477

Alternate gene names: 222524750

Gene position: 1871795-1872529 (Clockwise)

Preceding gene: 222524749

Following gene: 222524751

Centisome position: 35.53

GC content: 58.1

Gene sequence:

>735_bases
ATGGATCTTACTGCTGCCGAAGCAAGTCTTGCCGACGCAATTCAAACCGCTCGTGAGACACGCCGCACCCTGGTTGGTCG
AACAACCGATTGGGGTGTCGATCTCAATGGCGCTTATCGTATTCAGCGCATGCATCACCCGGATACCGCGTGTATTGGAT
ACAAACTTGGCCTGATTAGCCCGGCGAAGCAACGCCAGATGGGCTTAGCGCAACCAATCTATGGACGTATCAGCCGTTCC
ATGATCTACCAGCGTGAGGTACAGCTCACCCACTTCATTCAGCCGCGCCTGGAACCAGAGCTGGCTGTCGTCTTACGCCA
CAGCCTGCCGGCACACGCCGAACCCGGCATGATCGCTCGCGCCATCGGTGGTATCTTTCTGGGTGTGGATGTGCTCGATA
GCGTGTGGGCTGACTACCGCTTCAGCGCCGTTGAAGTCATCGCGGATAATGCCTCTGGTGGCGGATTTCTGCTCGGTGAG
TCGCTCCTCGACCAGGTACCAACCGGCGAGTTATGTTTGTACCTGAACGGTGAACTCTGCACTGCCGGTCAGGTCGCCGC
TCTGGGCAATATCGAGCAACAACTGGGCTGGCTGACACAGGCTGTCGGCGGTCTGGCTGCCGGACAAATCGTCTTTCTCG
GTTCGCCGGCTCAGGCCGTACCGGCCAGTGCCGGTGTCCTCGAAGTCACGTGCGGTAATACCATCCTTCAGGCGCGATTG
ATAGGAGATGCATGA

Upstream 100 bases:

>100_bases
GTTGCGCCAGCAAGCCTCTACGTCAACCCAGGGTCAGTAACTCGTTTGTTCAGAACATTTGCGATTCACCCGCATAACGT
GTCACCGCACGGAGATGACT

Downstream 100 bases:

>100_bases
TGGATTACCCGTTTTTTCACGTCAGTCACTACATTGATGGTCAGTTCGTTGACGGAGGATCGCGGTTTGATATTCTCTAT
CCGGCCACCAACCAGGTTAT

Product: Hydratase/decarboxylase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MDLTAAEASLADAIQTARETRRTLVGRTTDWGVDLNGAYRIQRMHHPDTACIGYKLGLISPAKQRQMGLAQPIYGRISRS
MIYQREVQLTHFIQPRLEPELAVVLRHSLPAHAEPGMIARAIGGIFLGVDVLDSVWADYRFSAVEVIADNASGGGFLLGE
SLLDQVPTGELCLYLNGELCTAGQVAALGNIEQQLGWLTQAVGGLAAGQIVFLGSPAQAVPASAGVLEVTCGNTILQARL
IGDA

Sequences:

>Translated_244_residues
MDLTAAEASLADAIQTARETRRTLVGRTTDWGVDLNGAYRIQRMHHPDTACIGYKLGLISPAKQRQMGLAQPIYGRISRS
MIYQREVQLTHFIQPRLEPELAVVLRHSLPAHAEPGMIARAIGGIFLGVDVLDSVWADYRFSAVEVIADNASGGGFLLGE
SLLDQVPTGELCLYLNGELCTAGQVAALGNIEQQLGWLTQAVGGLAAGQIVFLGSPAQAVPASAGVLEVTCGNTILQARL
IGDA
>Mature_244_residues
MDLTAAEASLADAIQTARETRRTLVGRTTDWGVDLNGAYRIQRMHHPDTACIGYKLGLISPAKQRQMGLAQPIYGRISRS
MIYQREVQLTHFIQPRLEPELAVVLRHSLPAHAEPGMIARAIGGIFLGVDVLDSVWADYRFSAVEVIADNASGGGFLLGE
SLLDQVPTGELCLYLNGELCTAGQVAALGNIEQQLGWLTQAVGGLAAGQIVFLGSPAQAVPASAGVLEVTCGNTILQARL
IGDA

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=214, Percent_Identity=28.9719626168224, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 25959; Mature: 25959

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLTAAEASLADAIQTARETRRTLVGRTTDWGVDLNGAYRIQRMHHPDTACIGYKLGLIS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCC
PAKQRQMGLAQPIYGRISRSMIYQREVQLTHFIQPRLEPELAVVLRHSLPAHAEPGMIAR
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHH
AIGGIFLGVDVLDSVWADYRFSAVEVIADNASGGGFLLGESLLDQVPTGELCLYLNGELC
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECHHHHHHCCCCCEEEEECCCEE
TAGQVAALGNIEQQLGWLTQAVGGLAAGQIVFLGSPAQAVPASAGVLEVTCGNTILQARL
CCCCHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHCCCCCCEEEEECCCEEEEEEE
IGDA
CCCC
>Mature Secondary Structure
MDLTAAEASLADAIQTARETRRTLVGRTTDWGVDLNGAYRIQRMHHPDTACIGYKLGLIS
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCEEEEEEECCCC
PAKQRQMGLAQPIYGRISRSMIYQREVQLTHFIQPRLEPELAVVLRHSLPAHAEPGMIAR
CHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHH
AIGGIFLGVDVLDSVWADYRFSAVEVIADNASGGGFLLGESLLDQVPTGELCLYLNGELC
HHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEECHHHHHHCCCCCEEEEECCCEE
TAGQVAALGNIEQQLGWLTQAVGGLAAGQIVFLGSPAQAVPASAGVLEVTCGNTILQARL
CCCCHHHHCCHHHHHHHHHHHHCCCCCCEEEEECCCCHHCCCCCCEEEEECCCEEEEEEE
IGDA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA