Click here to switch to the map view.

The map label for this gene is mshA [H]

Identifier: 222524677

GI number: 222524677

Start: 1786954

End: 1788102

Strand: Direct

Name: mshA [H]

Synonym: Chy400_1404

Alternate gene names: 222524677

Gene position: 1786954-1788102 (Clockwise)

Preceding gene: 222524676

Following gene: 222524678

Centisome position: 33.91

GC content: 56.05

Gene sequence:

>1149_bases
ATGCATATCGCTATCAACGCTCATCTGCTTGCGCATACCCACTCGTTTCGGCGGGCCGGTGTTTCTCACTATATCGAACA
AGTCTTACTCCACCTGGCCCAAATTGATCGCGAGAATCGCTACACCGTCTACACCACACGCGGCCTCGATCAGGCGGCCC
TCGGCTTACCGGCCAACTTCGTGGTCAAACCATCACGCTTACCAACCATTAACCCGCGCGTCCGGATTCCGTGGGAACAG
ATTATTGCGCCACTCATGTTGCGCGGCAAAGCAGACCTCTATCACGGCTGCCTTAACGTGGCACCGTTGCTCAGTCCGGT
GCCAACGGTAATCACCATCCACGATCTGGCCTTCATCCGCTTTCCGCAAACGTTTCGGGCCTACAATCGCATCTACCTCG
ATTTCGCCACCCGGCTCAGCGCCCGGCGGGCCAGTCGGATTCTCGTTGTTTCCGAGCACACAAAACGCGAAGTGGTGGGA
TTGCTCGGGGTTGATCCAGAACGGGTCGTTGTGACACCAAATGCCGTGCGTCATCACTTCCGTCCGCCTGATCCGGTTCA
ACTCGAGCAGTTCCGTGTTCGCCATAGTCTGCCGGAGCGCTTCATTTTATACGTCGGAACACTTGAACCGCGCAAGAATC
TGACGACGCTCCTCGAAGCGTTTGCCATCCTGAGCCGACAGGTGCCGACCGTTCCTCTCCTTATTGGCGGTGGAAAGGGC
TGGATGTATGAACCGATCTTTGCCCGTCTCGAACAATTGCAGTTACGTGACCGGGTAAAGTTCGTTGGTTATATTCCCGA
AGAGGAATTACCCCTGTGGTATGCAGCGGCTACCGTCTTTGTTTTTCCGTCGATATATGAAGGCTTCGGGATGCCACCAC
TCGAAGCAATGGCCTGCGGGACACCTGTCATCACCTCGAACACATCCAGCCTGCCGGAGGTAGTCGGCGATGCCGGGATA
ATGGTTTCACCCACCGATACCACTGCGCTTGCTGAAGCAATGCAGCGTATTCTGACCAGTGCTGATGTACGAGCAGATCT
GCGTACCCGTGGCCTGAAGCGCGCTCAACAGTTTTCCTGGACGCAGACAGCAATCAAGACCCTGGAAGCGTACCGGGCAG
CGTTGACACACCCCTCTGGTGGGGTATAA

Upstream 100 bases:

>100_bases
GCATGGCTCATCTACTTTCCGTTTAGTGATTGGGGATTGGTACCGCACCATCGCTACGAGACCAGTACTGCGGTAGCACC
TTAGTCAACCGCTCAATCGT

Downstream 100 bases:

>100_bases
TGAATGAGCATAGCCATGGATAGCGCTGGTGCAATAACGAGGAAGGAGTGCCGTATGATCGGTGGTCTTGGCTGGGGTGA
GCTGTTAATCATCTTGATTA

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MHIAINAHLLAHTHSFRRAGVSHYIEQVLLHLAQIDRENRYTVYTTRGLDQAALGLPANFVVKPSRLPTINPRVRIPWEQ
IIAPLMLRGKADLYHGCLNVAPLLSPVPTVITIHDLAFIRFPQTFRAYNRIYLDFATRLSARRASRILVVSEHTKREVVG
LLGVDPERVVVTPNAVRHHFRPPDPVQLEQFRVRHSLPERFILYVGTLEPRKNLTTLLEAFAILSRQVPTVPLLIGGGKG
WMYEPIFARLEQLQLRDRVKFVGYIPEEELPLWYAAATVFVFPSIYEGFGMPPLEAMACGTPVITSNTSSLPEVVGDAGI
MVSPTDTTALAEAMQRILTSADVRADLRTRGLKRAQQFSWTQTAIKTLEAYRAALTHPSGGV

Sequences:

>Translated_382_residues
MHIAINAHLLAHTHSFRRAGVSHYIEQVLLHLAQIDRENRYTVYTTRGLDQAALGLPANFVVKPSRLPTINPRVRIPWEQ
IIAPLMLRGKADLYHGCLNVAPLLSPVPTVITIHDLAFIRFPQTFRAYNRIYLDFATRLSARRASRILVVSEHTKREVVG
LLGVDPERVVVTPNAVRHHFRPPDPVQLEQFRVRHSLPERFILYVGTLEPRKNLTTLLEAFAILSRQVPTVPLLIGGGKG
WMYEPIFARLEQLQLRDRVKFVGYIPEEELPLWYAAATVFVFPSIYEGFGMPPLEAMACGTPVITSNTSSLPEVVGDAGI
MVSPTDTTALAEAMQRILTSADVRADLRTRGLKRAQQFSWTQTAIKTLEAYRAALTHPSGGV
>Mature_382_residues
MHIAINAHLLAHTHSFRRAGVSHYIEQVLLHLAQIDRENRYTVYTTRGLDQAALGLPANFVVKPSRLPTINPRVRIPWEQ
IIAPLMLRGKADLYHGCLNVAPLLSPVPTVITIHDLAFIRFPQTFRAYNRIYLDFATRLSARRASRILVVSEHTKREVVG
LLGVDPERVVVTPNAVRHHFRPPDPVQLEQFRVRHSLPERFILYVGTLEPRKNLTTLLEAFAILSRQVPTVPLLIGGGKG
WMYEPIFARLEQLQLRDRVKFVGYIPEEELPLWYAAATVFVFPSIYEGFGMPPLEAMACGTPVITSNTSSLPEVVGDAGI
MVSPTDTTALAEAMQRILTSADVRADLRTRGLKRAQQFSWTQTAIKTLEAYRAALTHPSGGV

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Homo sapiens, GI11863130, Length=194, Percent_Identity=28.3505154639175, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17532709, Length=325, Percent_Identity=24.9230769230769, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI9755344, Length=270, Percent_Identity=22.2222222222222, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 42841; Mature: 42841

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHIAINAHLLAHTHSFRRAGVSHYIEQVLLHLAQIDRENRYTVYTTRGLDQAALGLPANF
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCCE
VVKPSRLPTINPRVRIPWEQIIAPLMLRGKADLYHGCLNVAPLLSPVPTVITIHDLAFIR
EECCCCCCCCCCCEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHC
FPQTFRAYNRIYLDFATRLSARRASRILVVSEHTKREVVGLLGVDPERVVVTPNAVRHHF
CCHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCCCCCCEEEECCHHHHHCC
RPPDPVQLEQFRVRHSLPERFILYVGTLEPRKNLTTLLEAFAILSRQVPTVPLLIGGGKG
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
WMYEPIFARLEQLQLRDRVKFVGYIPEEELPLWYAAATVFVFPSIYEGFGMPPLEAMACG
CCCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
TPVITSNTSSLPEVVGDAGIMVSPTDTTALAEAMQRILTSADVRADLRTRGLKRAQQFSW
CCEEECCCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQTAIKTLEAYRAALTHPSGGV
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MHIAINAHLLAHTHSFRRAGVSHYIEQVLLHLAQIDRENRYTVYTTRGLDQAALGLPANF
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHCCCCCE
VVKPSRLPTINPRVRIPWEQIIAPLMLRGKADLYHGCLNVAPLLSPVPTVITIHDLAFIR
EECCCCCCCCCCCEECCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHC
FPQTFRAYNRIYLDFATRLSARRASRILVVSEHTKREVVGLLGVDPERVVVTPNAVRHHF
CCHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHCCCCCCEEEECCHHHHHCC
RPPDPVQLEQFRVRHSLPERFILYVGTLEPRKNLTTLLEAFAILSRQVPTVPLLIGGGKG
CCCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCC
WMYEPIFARLEQLQLRDRVKFVGYIPEEELPLWYAAATVFVFPSIYEGFGMPPLEAMACG
CCCCHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHCC
TPVITSNTSSLPEVVGDAGIMVSPTDTTALAEAMQRILTSADVRADLRTRGLKRAQQFSW
CCEEECCCCHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQTAIKTLEAYRAALTHPSGGV
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA