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The map label for this gene is lon [H]

Identifier: 222524648

GI number: 222524648

Start: 1753864

End: 1754532

Strand: Direct

Name: lon [H]

Synonym: Chy400_1373

Alternate gene names: 222524648

Gene position: 1753864-1754532 (Clockwise)

Preceding gene: 222524647

Following gene: 222524649

Centisome position: 33.29

GC content: 56.05

Gene sequence:

>669_bases
ATGGAACACCTTCTGCCATTATTTCCACTCGGTTCGCTCCTCTTCCCCGGCGGCACAATGAGTCTGCACATTTTTGAGCA
ACGTTATCGCCTGATGATTGGGCACTGTCTGGCCGGGGAACAACGGTTTGGGATTGTCCTGCTCCGCCGGGGACACGAGG
TCATAGAAGGCCGGGTGGTTGATGTTGCCCCGGAGCCATACGATGTTGGCACCGTCGCCATCATTCAGGAGTATCTCAAG
CTGGAAGATGGCCGTTACCTGTTGCACGTGATGGGTCAGCAGCGCTTTCGCATCCTTCAGATCATCGACCAATCACCGTA
TCTGGTGGCAAAAGTGCAGCTGCTTCCTGAACAGACCGATAACGAGAGTATCGCTGCGGCAACTGAACTGCGCAATACCT
ATCAGCGGTACTGGGAGCGCATTGCTACCATCACCGGAACCGAGATCGAGGTCGAGTCGTTGCCGCTCGACCCGATCAAG
CTGGGGTACATTCTGGCCGACCGGTTGCAGATCGATATGGCCCAGAAACAACGCTGGCTGGAAACCGACGTCACCGACCG
TTTACGCAGTCTGACCATGGCCCTGCGGACAGAAATGGCAATCTTGCCGCACGGCCCACAGGGTCTTGATCCGTCGAGCC
TGTTGGGTGGTTGGAATAGTTTGAACTGA

Upstream 100 bases:

>100_bases
GACGATGTCAGGCCCGGAAATAGAACTGCTGATCGATCTCAACCTTGGCCCGGCTGAAACAACCGTCTGGACCTGCACAT
GGACAGATGGGTAAATCGGT

Downstream 100 bases:

>100_bases
TTTATCAACAAAGTCATGATCATCGGTTCTTGCACAATCCATCTCCACATCGCCACTGCACAATCGCTGAAAGAGAAGCG
CCAGGTTTTGCGCTCACTTA

Product: peptidase S16 lon domain-containing protein

Products: NA

Alternate protein names: ATP-dependent protease La [H]

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MEHLLPLFPLGSLLFPGGTMSLHIFEQRYRLMIGHCLAGEQRFGIVLLRRGHEVIEGRVVDVAPEPYDVGTVAIIQEYLK
LEDGRYLLHVMGQQRFRILQIIDQSPYLVAKVQLLPEQTDNESIAAATELRNTYQRYWERIATITGTEIEVESLPLDPIK
LGYILADRLQIDMAQKQRWLETDVTDRLRSLTMALRTEMAILPHGPQGLDPSSLLGGWNSLN

Sequences:

>Translated_222_residues
MEHLLPLFPLGSLLFPGGTMSLHIFEQRYRLMIGHCLAGEQRFGIVLLRRGHEVIEGRVVDVAPEPYDVGTVAIIQEYLK
LEDGRYLLHVMGQQRFRILQIIDQSPYLVAKVQLLPEQTDNESIAAATELRNTYQRYWERIATITGTEIEVESLPLDPIK
LGYILADRLQIDMAQKQRWLETDVTDRLRSLTMALRTEMAILPHGPQGLDPSSLLGGWNSLN
>Mature_222_residues
MEHLLPLFPLGSLLFPGGTMSLHIFEQRYRLMIGHCLAGEQRFGIVLLRRGHEVIEGRVVDVAPEPYDVGTVAIIQEYLK
LEDGRYLLHVMGQQRFRILQIIDQSPYLVAKVQLLPEQTDNESIAAATELRNTYQRYWERIATITGTEIEVESLPLDPIK
LGYILADRLQIDMAQKQRWLETDVTDRLRSLTMALRTEMAILPHGPQGLDPSSLLGGWNSLN

Specific function: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced

COG id: COG2802

COG function: function code R; Uncharacterized protein, similar to the N-terminal domain of Lon protease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Lon domain [H]

Homologues:

None

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008269
- InterPro:   IPR004815
- InterPro:   IPR003111
- InterPro:   IPR008268
- InterPro:   IPR001984
- InterPro:   IPR015947
- InterPro:   IPR020568 [H]

Pfam domain/function: PF00004 AAA; PF02190 LON; PF05362 Lon_C [H]

EC number: =3.4.21.53 [H]

Molecular weight: Translated: 25288; Mature: 25288

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHLLPLFPLGSLLFPGGTMSLHIFEQRYRLMIGHCLAGEQRFGIVLLRRGHEVIEGRVV
CCCCCCCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCEEE
DVAPEPYDVGTVAIIQEYLKLEDGRYLLHVMGQQRFRILQIIDQSPYLVAKVQLLPEQTD
EECCCCCCCHHHHHHHHHHHHCCCCEEEEHHCHHHHHHHHHHCCCCEEEEEEEECCCCCC
NESIAAATELRNTYQRYWERIATITGTEIEVESLPLDPIKLGYILADRLQIDMAQKQRWL
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
ETDVTDRLRSLTMALRTEMAILPHGPQGLDPSSLLGGWNSLN
HCCHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure
MEHLLPLFPLGSLLFPGGTMSLHIFEQRYRLMIGHCLAGEQRFGIVLLRRGHEVIEGRVV
CCCCCCCCCCHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCEEE
DVAPEPYDVGTVAIIQEYLKLEDGRYLLHVMGQQRFRILQIIDQSPYLVAKVQLLPEQTD
EECCCCCCCHHHHHHHHHHHHCCCCEEEEHHCHHHHHHHHHHCCCCEEEEEEEECCCCCC
NESIAAATELRNTYQRYWERIATITGTEIEVESLPLDPIKLGYILADRLQIDMAQKQRWL
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHH
ETDVTDRLRSLTMALRTEMAILPHGPQGLDPSSLLGGWNSLN
HCCHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA