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The map label for this gene is luxQ [H]

Identifier: 222524634

GI number: 222524634

Start: 1735306

End: 1736919

Strand: Direct

Name: luxQ [H]

Synonym: Chy400_1358

Alternate gene names: 222524634

Gene position: 1735306-1736919 (Clockwise)

Preceding gene: 222524633

Following gene: 222524635

Centisome position: 32.93

GC content: 54.77

Gene sequence:

>1614_bases
ATGTCGTTATCGGTTGAACAACGGGTATTGATTGAAACCGGGAGTGCGTATGTCGTGGTCGATCCTGATCTGCGCATCCA
GAGTGCCGGTGGCATGCTGGCCCTGCTTGGCGGTAAACCGCCGATTGGGGGGCATTTGCTCGATTTACTGCCGGAATTAT
TTGGTAATGAAGCGGCACTAGACGAGATATTGCACGGCGAACGGGATCGTCTTTACTTACCGTTGATCAACCGTCAGATG
CCAGATGGCTCTACCCTCTATATCGATCTCTTAACGATCCCTCTTACCGATAAGGATGGGCGCATCACCGGTCTGATCCA
GATCGTGACCGATACGACCCAACGTAGTGTTATCGAACAACTACGCTCCCAACAGCGTAATGAATTACAGTTGCTGAAAG
ATCGGCTGCAACGGCAGAATGTCGAGCTGGCGCGCATCAATGCCAGTTTGCTCAAGACCACGAAGATCAAAGACGAGTTT
CTGGCCAGTATGAGCCACGAGATACGCACTCCGCTCACGGCCATTTTGGGCATGGTAGACCTGCTGCGCGCTCAGTTGGT
TGGTCCATTGAGTGATGAGCAGATGGGCGCGATTGATGGCATTAAAAAAGGCAGTCAGCATCTGCTCTCGCTCATCAATG
ACTATCTCGATATTGCCAAAGTTGAAGCGGGTCGGATGGAGCTAGACCTGACTCCAGTTTCAGTGCAGGATGTCTGCATG
TCGTTGCGCCCACTGGTGGCTGACCTCATCAGGCGCGCCAATCTGTCATTGATCTTCGACATTGATTCTGCGGTTCAGGT
CATTCTGGCTGATGCACGACGGCTGCGCCAGATTTTGATTAATCTGCTCTCGAATGCCATCAAGTTCACCCCAGCCGGTG
GTAAGGTGGGGCTAGAGGTACGTGGTGAGCCAGAACGGGGAGCGGTGCGCTTTACAGTATGGGACACCGGGATTGGGATT
TCGGCTGAAGATGCTGTGCGCTTATTTGAGCCATTCCAGCAGATTGAGAGTGAACGGCAGAAAGAGGTGACCGGTAGTGG
TCTGGGGCTGGCACTGGTGGCCAAGCTGGTTCGCCTTCACGGTGGCAGTGTTCGCGTCGAAAGTGAAGTAGGGGTTGGGA
GTCGTTTTCACGTCACGCTGCCCTGGGAACCGGACGAGCAATATCGCTTTCTGGAACAACTCGATCAGCAAGAGCGGGAG
GAAGATACTCACCCAACCGAGTTGCCTGCCGCCTCGCCACGGGCCGGTGATCGCCCACTCCTGATGGTTGAAGATGATGT
CGCCAGTGCTACCTTGATTGCCGACTACCTGCGCCGCTGTGGGTATCGGGTAGTGCATGTCGAGTCAGGCGAAGAGGCGC
TGGCCTACATTCAGGGTGAATTGCCGTGTTTAATCCTCCTCGATGTCCGCCTGCGCACGATGAGCGGTTTTGAAGTGATG
CAGCACTTGCGCAGTCAGGTAGCCACTCGTGATTTACCAGTTCTGGTCTTAACGGCGCTGGCTATGCCCGGCGACCGTGA
ACGGTGTCTCGAAGCCGGAGCTGATGAGTACCTCGCCAAACCGATTCGTTTACGGCTCCTCGCCGAACGGATTGCCGCGT
TGCTTGAACGATAG

Upstream 100 bases:

>100_bases
ACGGTCGCCGTGAACGAGTGTCTGGCCTATCAATTCAGCAGGTGGATGAACCTTTGACCGCTGGCGACCTGATGCATAAC
AGCCACAAGCGAGGTAGACG

Downstream 100 bases:

>100_bases
GGCGTAATTAGCAAATCTTCGTTGACATTGATAGGGGCAACACTGCTGATACCACCAATCGCTGTTCATTAGTCCAGTAA
TGGGATTTGCCTCGCTCTGA

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MSLSVEQRVLIETGSAYVVVDPDLRIQSAGGMLALLGGKPPIGGHLLDLLPELFGNEAALDEILHGERDRLYLPLINRQM
PDGSTLYIDLLTIPLTDKDGRITGLIQIVTDTTQRSVIEQLRSQQRNELQLLKDRLQRQNVELARINASLLKTTKIKDEF
LASMSHEIRTPLTAILGMVDLLRAQLVGPLSDEQMGAIDGIKKGSQHLLSLINDYLDIAKVEAGRMELDLTPVSVQDVCM
SLRPLVADLIRRANLSLIFDIDSAVQVILADARRLRQILINLLSNAIKFTPAGGKVGLEVRGEPERGAVRFTVWDTGIGI
SAEDAVRLFEPFQQIESERQKEVTGSGLGLALVAKLVRLHGGSVRVESEVGVGSRFHVTLPWEPDEQYRFLEQLDQQERE
EDTHPTELPAASPRAGDRPLLMVEDDVASATLIADYLRRCGYRVVHVESGEEALAYIQGELPCLILLDVRLRTMSGFEVM
QHLRSQVATRDLPVLVLTALAMPGDRERCLEAGADEYLAKPIRLRLLAERIAALLER

Sequences:

>Translated_537_residues
MSLSVEQRVLIETGSAYVVVDPDLRIQSAGGMLALLGGKPPIGGHLLDLLPELFGNEAALDEILHGERDRLYLPLINRQM
PDGSTLYIDLLTIPLTDKDGRITGLIQIVTDTTQRSVIEQLRSQQRNELQLLKDRLQRQNVELARINASLLKTTKIKDEF
LASMSHEIRTPLTAILGMVDLLRAQLVGPLSDEQMGAIDGIKKGSQHLLSLINDYLDIAKVEAGRMELDLTPVSVQDVCM
SLRPLVADLIRRANLSLIFDIDSAVQVILADARRLRQILINLLSNAIKFTPAGGKVGLEVRGEPERGAVRFTVWDTGIGI
SAEDAVRLFEPFQQIESERQKEVTGSGLGLALVAKLVRLHGGSVRVESEVGVGSRFHVTLPWEPDEQYRFLEQLDQQERE
EDTHPTELPAASPRAGDRPLLMVEDDVASATLIADYLRRCGYRVVHVESGEEALAYIQGELPCLILLDVRLRTMSGFEVM
QHLRSQVATRDLPVLVLTALAMPGDRERCLEAGADEYLAKPIRLRLLAERIAALLER
>Mature_536_residues
SLSVEQRVLIETGSAYVVVDPDLRIQSAGGMLALLGGKPPIGGHLLDLLPELFGNEAALDEILHGERDRLYLPLINRQMP
DGSTLYIDLLTIPLTDKDGRITGLIQIVTDTTQRSVIEQLRSQQRNELQLLKDRLQRQNVELARINASLLKTTKIKDEFL
ASMSHEIRTPLTAILGMVDLLRAQLVGPLSDEQMGAIDGIKKGSQHLLSLINDYLDIAKVEAGRMELDLTPVSVQDVCMS
LRPLVADLIRRANLSLIFDIDSAVQVILADARRLRQILINLLSNAIKFTPAGGKVGLEVRGEPERGAVRFTVWDTGIGIS
AEDAVRLFEPFQQIESERQKEVTGSGLGLALVAKLVRLHGGSVRVESEVGVGSRFHVTLPWEPDEQYRFLEQLDQQEREE
DTHPTELPAASPRAGDRPLLMVEDDVASATLIADYLRRCGYRVVHVESGEEALAYIQGELPCLILLDVRLRTMSGFEVMQ
HLRSQVATRDLPVLVLTALAMPGDRERCLEAGADEYLAKPIRLRLLAERIAALLER

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=390, Percent_Identity=32.0512820512821, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI48994928, Length=460, Percent_Identity=30, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI145693157, Length=288, Percent_Identity=35.4166666666667, Blast_Score=149, Evalue=6e-37,
Organism=Escherichia coli, GI1789149, Length=273, Percent_Identity=34.7985347985348, Blast_Score=142, Evalue=8e-35,
Organism=Escherichia coli, GI87081816, Length=378, Percent_Identity=30.1587301587302, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI1786600, Length=279, Percent_Identity=29.7491039426523, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1786912, Length=228, Percent_Identity=30.7017543859649, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI87082128, Length=230, Percent_Identity=30.8695652173913, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=30, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=26.2745098039216, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=253, Percent_Identity=29.6442687747036, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=29.3859649122807, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=37.5, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=27.027027027027, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=31.4009661835749, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=29.2372881355932, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1788394, Length=134, Percent_Identity=34.3283582089552, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87082012, Length=118, Percent_Identity=33.0508474576271, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59509; Mature: 59378

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSVEQRVLIETGSAYVVVDPDLRIQSAGGMLALLGGKPPIGGHLLDLLPELFGNEAAL
CCCCCCCEEEEECCCEEEEECCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHH
DEILHGERDRLYLPLINRQMPDGSTLYIDLLTIPLTDKDGRITGLIQIVTDTTQRSVIEQ
HHHHCCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCHHHHHHHH
LRSQQRNELQLLKDRLQRQNVELARINASLLKTTKIKDEFLASMSHEIRTPLTAILGMVD
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRAQLVGPLSDEQMGAIDGIKKGSQHLLSLINDYLDIAKVEAGRMELDLTPVSVQDVCM
HHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
SLRPLVADLIRRANLSLIFDIDSAVQVILADARRLRQILINLLSNAIKFTPAGGKVGLEV
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEE
RGEPERGAVRFTVWDTGIGISAEDAVRLFEPFQQIESERQKEVTGSGLGLALVAKLVRLH
CCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GGSVRVESEVGVGSRFHVTLPWEPDEQYRFLEQLDQQEREEDTHPTELPAASPRAGDRPL
CCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCE
LMVEDDVASATLIADYLRRCGYRVVHVESGEEALAYIQGELPCLILLDVRLRTMSGFEVM
EEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCEEEEEEHHHHHCCHHHHH
QHLRSQVATRDLPVLVLTALAMPGDRERCLEAGADEYLAKPIRLRLLAERIAALLER
HHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLSVEQRVLIETGSAYVVVDPDLRIQSAGGMLALLGGKPPIGGHLLDLLPELFGNEAAL
CCCCCCEEEEECCCEEEEECCCCEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCHHHH
DEILHGERDRLYLPLINRQMPDGSTLYIDLLTIPLTDKDGRITGLIQIVTDTTQRSVIEQ
HHHHCCCCCEEEEEECCCCCCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCHHHHHHHH
LRSQQRNELQLLKDRLQRQNVELARINASLLKTTKIKDEFLASMSHEIRTPLTAILGMVD
HHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRAQLVGPLSDEQMGAIDGIKKGSQHLLSLINDYLDIAKVEAGRMELDLTPVSVQDVCM
HHHHHHCCCCCCCHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
SLRPLVADLIRRANLSLIFDIDSAVQVILADARRLRQILINLLSNAIKFTPAGGKVGLEV
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEE
RGEPERGAVRFTVWDTGIGISAEDAVRLFEPFQQIESERQKEVTGSGLGLALVAKLVRLH
CCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GGSVRVESEVGVGSRFHVTLPWEPDEQYRFLEQLDQQEREEDTHPTELPAASPRAGDRPL
CCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCE
LMVEDDVASATLIADYLRRCGYRVVHVESGEEALAYIQGELPCLILLDVRLRTMSGFEVM
EEEECCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCEEEEEEHHHHHCCHHHHH
QHLRSQVATRDLPVLVLTALAMPGDRERCLEAGADEYLAKPIRLRLLAERIAALLER
HHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]